Prakanong2005

Mark

Its getting totally off topic and you are welcome to your beleifs - as thatrs all they are - you have no scientific evidence while the weight of effifacy and effectiveness is on the side of vaccines.

Your anecdotes are not data and no matter what the evidence you will always choose to belive in conspiracies of dunces.

Good luck with your life

BTW: Today may be my very last day working on the vaccines side - I am still waiting of a firm job offer but I will be leaving this site today. I have worked with so many dedicated and absolutely brilliant people dedicated to the cause of improving health and saving lives its humbling - I have learned so much and take a lot away with me.

As long as the clinic or hospital store the vacciens at the right temp and do not break the cold chain one place is about as good as the other.

If this was BKK I would say the Thai Red Cross due to price and their experience.

PS: Hep A is now thought to be for life and not just the initial 10 years it was thought to last.

From the WHO site - the PMS (Post Marketing studies are now pushing the effifacy right out

"Although one dose of vaccine provides at least short-term protection, the manufacturers currently recommend two doses to ensure long-term protection. In studies evaluating the duration of protection of two or more doses of hepatitis A vaccine, 99%–100% of vaccinated individuals had levels of antibody indicative of protection five to eight years after vaccination. Kinetic models of antibody decay indicate that the duration of protection is likely to be at least 20 years, and possibly lifelong. Post-marketing surveillance studies are needed to monitor vaccine-induced long-term protection, and to determine the need for booster doses of vaccine. "

It was said on the morning BBC News that 25% of those schools inspected by Home Office staff were dodgy and removed fom approved establishments.

Maybe the barrier to being approved should be made higher?

(Those of us of a certain age might snigger at the term "Approved Schools" though ) ;-)

Because neither you nor I have 1 million USD my dear chap

The Aussies like the USA just do not have the league or the structure to produce a world cup winning side in the next 20 years.

Bel Aire Princess on Soi 5 - I have stayed there about 40 times now

I get a suite there for 2000++ but that is airline crew discount (don't ask ) but you will get a superior room for that.

Its being done up as well.

It was a blatant BS call from the ref, We would play england anywhere in the world I think, you can have the home court advantage, it wouldnt matter.

We only have 20mill people, and we are the best in the world at alot of sports. Soccer will be next

Like I said to an American who said the same in 94

I will wager you 1000USD that you do not win the football World Cup before 2020

"When do you lot ditch the pound for the Euro?" LOL

I have been working in the Eurozone for the last 4 years and was convinced before I came here and that was at first reinforced initially that the UK should adopt the Euro.

My views have now changed on that though - not for irrational patriotic reasons but because i think we need the flexibility to control interst rates etc ourselves for a stronger economy.

Sorry totally off topic

This has been going on for years and years.

Its a good time for a re-hash of the story though with the Home Office being very much in the limelight as of late.

I have worked at places where Zimbabwean and Cameroonian students were working on Student visa's - they are allowed to work part time but these were full time

Is it just me, or are we seeing an increase in the shootings of farang here? Or are the media just taking up these stories more and more?

Hope this guy is okay, and that the shooter is caught.

I do not know if it is an increase, our perception or that the information is more easily accessed.

My opinion is that it is an increase but that is only a gut feeling

Mark

The CDC is a very good site but come on - Smallpox vaccine - thats such a universal vaccine now isn't it not - why not ask about Jenner's milk maids?

I thought you might even have brought up the discrdited crap about MMR

As for that old chestnut about mercury and vaccines that was dead and buried before it started for anyone with a brain - its a different type of mercury and the amounts are not enough to harm.

Antway most pediatric vaccines are made without thirmersol now anyway or are moving that way but the basic premise that it was harmful in vaccines is wrong

Every single medicine including vaccines will have AE's for some population sample - the fact is these AE's are very very rare in vaccines.

The fact is vaccines do far more harm than good - they have saved millions of lives and from the devastating effects of many diseases that were common in our parents times including polio, measles TB etc.

The fact is vaccines are going to do even more good in the future - that include both the near term and the mid-term.

This year we will hve a vaccine against cervical cancer which kills 100's of thousands of women each year - disproporionately so in the developing world - a vaccination prgramme will go along way to helping with this

The Malaria vaccines will save 100's of thousands of lives a year - that will be running soon and with the help of Bill and Miranda Gates it would not be so.

I am sure the ne TB vaccine against the resistant strain will be along and hopefully in 15-20 years an HIV vaccine

Mengingitis and Rota virus kil many in the developing worl each year - vacines are helping right now

All in all are you against vaccines?

Of course ethically any new oncology trials must be trialled first in those who have had all other avenues explored.

I have not worked on vaccine oncology trials but have on pharma and its pretty depressing reading CRF's due to the prognosis of most subjects - especially in early stage trials.

I do think Mark has a bee in his bonnet about vaccines in general and not just therapeutic oncology trials though.

Its just a blessing that most rational educated people do not follow quacks advice about vaccines and thus we delivered 1.5 billion doses last year.

With the launch of recent vaccines like Rota and in the near future for Cervical Cancer and Malaria we will be saving 100,000's more each year - I do not see laughing and colonic irrigation doing that

The science says it all - nuff said

"Aussies dont dive, coz were real men. We play fair and square."

Bhwaaaaaaaa haaaaaaaa

I have used my short term/Temp Belgian ID card - the paper one not the 5 year plastic one

I did it as an experiment only though just to see if it was accepted

Mark

Just what research have you done yourself into vaccines?

I work at the biggest vaccine research site in the world at the company with the largest share of the vaccine market in the world - at least until Friday I do.

I think you proved you talk pish in your silly statement about clinical trials not taking place on women so your even sillier inference about vacines should be scorned too.

You speak absolute rubbish and are show to do so.

Pray tell me your research into vaccines and your qualifications in this area?

I assume if you ever have children (Buddha forbid) you will not be having them vaccinated and instead telling them to laugh and they will never catch any childhood diseases that can kill or cause irreparable damage?

While you are on it can you show me any clinical studies showing any of the quack treatments you propose have any effifacy or effectiveness - thought not!!!!

Do you know the greatest advancement in medical science over the last 200 years?

The randomised, double clind clinical trial - because we can now tell what works and what does not - guess what most of the quack remedies proposed by the charlatans proposing most alternative therapies can just not stand up to science

Try www.quackwatch.com in your independent research matey boy

I think there should only be a penalty in soccer if there is a head high tackle.

You really are not playing with the full deck are you?

I think the thai term is something like "Mai tem teng"

Well I guess we cant win every sport

Yeah - who currently has the Ashes and the Rugby World Cup?

We will not retain them of course but we have them in our sweaty mitts right now

Exactly Maestro

The Thai FDA has not got such a bad name in the pharma industry actually.

As for decades behind well I know its an exaggeration but a lot of that is due to the pharma companies themselves.

They just do not license many products in Thailand due to market conditions ie it would cost too much to conduct studies in Thailand (sometimes FDA's require local data) submit other applications etc as the returns would not justify this.

Just a quck note about new drugs in Thailand

A new registered drug is only available in Hospitals or clinics for the first 2 years it is registered in Thailand according to the Thai FDA

Generics should follow the WTO standards on patent protection and still have to go through a registration process in Thailand.

The name in Thailand for the low dose anti-smoking stuff sems to be quomen

"US Brand Name: Wellbutrin / Wellbutrin SR / Wellbutrin XL

Other Brand Names: Zyban (for smoking cessation)

Odranal (Colombia)

Quomen (Thailand)

Well (Korea)

Zyban LP (France)

Zyban Sustained Release (Australia)"

Depending on Cancer type there are early stage vaccine trials taking place right now.

If you like I could also enquire with our Country Medical Director for Thailand where she would reccomend for treatment in Bangkok!

Sorry Mark but this is absolute pish and you do not know what you are talking about

"Also most drugs are NOT tested on women as thier hormone cycles make it much more difficult. Yet of course they dish them out easily enough."

I work in clinical trials and have done so in pharma and vaccines and I can assure you most drugs ARE tested on women.

Yes there are certain exclusion criteria and the woman is pregnancy tested on each visit and prior to study start and will not initiate the trial or continue if pregnant

But

Healthy non-pregnant women who meet all the inclusion criteria are well represented in clinical trials where the drug is aimed at both sexes - it would not get licensed if not - think about it sensibly please!!!!!!

First of all OP - I wish your mother the best.

The Big fuss in the UK now is about the availability of Herceptin from Roche in early stage Breast Cancer rather than just late stage.

It was only initially available for late stage but after a campaign it os now going to be available country wide.

The results on some types of breast cancer are very good.

I will add the proviso though that i can not see it being that much cheaper in Thailand - i only say this as a friend who sadly died of colon cancer was having treatment at Bumrungrad with a drug not available on the NHS in the UK.

Here is a link

http://www.cancerhelp.org.uk/help/default.asp?page=12797

most people should take precautions to protect themselves and look after their own health with regard to this bird flu , but should an outbreak occur , i believe that it would be very difficult for any foriegner living here to get medication or treatment ahead of locals.

it is at times like that that our governments representatives here should be able and willing to offer some assistance to any genuine hardship cases.

I bet there is enough Tamiflu in the Embassy for all staff and family members

I know the company I work at has enough for all first circle family members in case of a pandemic and we will be first in line for the vaccine too.

Pattaya is a dump, foreigners only move there for cheap beer and even cheaper woman.

Yet another wannabe Pattayan who feels compelled to slag off the place at every opportunity because he can only dream of living there...

Well he is from Newcastle is he not

Sheryl

See you PM - some stuff I can not post on a public board!

I will check the Dengue stuff for you and try to get some links - I was at a very interesting presentation for this in early May.

I know about "Malarine" and you are right some people do mistake this and this may be the source of rumours Malarone is availa in Cambodia

I am pretty sure the trial is over and if you click on the link it gives results - ie it was 100% effective in this trial but with AE's and one SAE.

"Atovaquone/proguanil was 100% effective (PP population) for treating acute, uncomplicated P. falciparum malaria with no recrudescence reported during the entire 28-day follow-up period. Furthermore, the elimination of P. falciparum parasitemia was accompanied by resolution of the clinical signs and symptoms of malaria. Adverse events were reported in 66 subjects, the most frequent being dyspepsia, upper respiratory tract infection and vomiting. The only serious adverse event, hypotension, was reported in one subject. No deaths were reported."

The results have to be posted withing 6 months of LSLV (Last Subject Last Visit) according to the agreement with the New York Attorney General on posting clinical trial results.

I know its not licensed in Cambodia but we had heard of it being avail there for treatment.

There is a dual strategy for licencing for both treatment and prophylactic use - some countries have one or the other or both or none

The last list I saw of country availability was at least 3 years old and its not an area in which I work.

AFAIK they are not trialling the Malaria vaccine in Thailand but the Dengue one is well underway.