Little to no impact on daily life tbh, you just need to make sure you don't live within earshot of a mosque as that can disturb your sleep. Also in my area of the city, 25% of the population are of other religions so there's some balance.
As in much of SE Asia, random attacks on foreigners are rare. If a foreigner does get attacked, there's usually a reason for it. I walk around the city regularly and use public transport most days and have never felt threatened, but obviously still keep my wits about me and take usual precautions.
There's plenty of nightlife, including pub-type bars, but certainly not on the scale of Bangkok. The vast majority of people here don't drink, so nightlife is clustered around the central commercial/business area and the more affluent suburbs.