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Pottinger

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Posts posted by Pottinger

  1. "LITTLE WANDERING WREN

    Jenny is the content creator and chief explorer at Little Wandering Wren. She is both a Brit and an Aussie who currently has her nest in Bangkok. She is constantly travelling and brings us her light-hearted, birds-eye view of the world. Little Wandering Wren was a winner of the Tourism Authority of Thailand's International Blogger competition 2019."

     

    "Feather-footed through the plashy fen passes the questing vole". 

     

    I'm so glad the bathtub was gorgeous.

    • Like 1
  2. Mostly biochemical jargon, but confirms what the OP stated:

     

    "Novel COVID-19 therapeutics are urgently needed. We generated a phage-displayed human antibody VH domain library from which we identified a high-affinity VH binder ab8. Bivalent VH, VH-Fc ab8 bound with high avidity to membrane-associated S glycoprotein and to mutants found in patients. It potently neutralized mouse adapted SARS-CoV-2 in wild type mice at a dose as low as 2 mg/kg and exhibited high prophylactic and therapeutic efficacy in a hamster model of SARS-CoV-2 infection, possibly enhanced by its relatively small size. Electron microscopy combined with scanning mutagenesis identified ab8 interactions with all three S protomers and showed how ab8 neutralized the virus by directly interfering with ACE2 binding. VH-Fc ab8 did not aggregate and did not bind to 5300 human membrane-associated proteins. The potent neutralization activity of VH-Fc ab8 combined with good developability properties and cross-reactivity to SARS-CoV-2 mutants provide a strong rationale for its evaluation as a COVID-19 therapeutic."

  3. 30 minutes ago, carlyai said:

    It is called The Natural Approach and is/ was taught at AUA language centres. Dr Brown was still the director there when I learnt Thai. 

    The problem is that not many people can just practice the natural approach for the years required. I practiced the natural and structured approaches together and also did the reading and writing course. 

    From my point of view, the natural approach is great, just listening, but I needed other approaches as well. 

     

    I also did Dr Brown's Natural Approach courses, including reading and writing, for about five months full time, at the old AUA on Rajadamri, back in the 1980s. I found it marvellous, but I had fellow students who could not get past what Dr Brown talks of in his book - the constant analysis, comparison and associated chatter that goes on in the adult brain, which interferes with learning language as a child does - purely, without judgement. 

       I guess it's a case of different strokes for different folks - as I say, I found it fascinating and liberating as compared to the rote learning method by which I learned, and never became fluent in, French at school.

       Incidentally, I don't recall Dr Brown advocating such a lengthy period of 'just shut up and listen' as the OP suggests. Certainly, in the time I was there, we were encouraged to just sit and listen for the first few weeks, not years, and to allow speech to arrive 'naturally', as we felt comprehension improve and comment or question arise.

    • Like 1
  4. 20 minutes ago, meechai said:

     

    I expect this behavior to continue with any foreigner being the target as things get worse

    economically in Thailand

    Good time to sell the gold chains, or put them away safely.

  5. 25 minutes ago, Laughing Gravy said:

    This is true.

    In 2003 the then governor of Bangkok had a brain wave and thought why don't we computerise all the traffic lights, so no need for half (or more) Police to man them.

     

    Sadly this great idea didn't go down well with the Police and they computerised the traffic lights and kept the Police. Replacing those mafia types from losing their extra income is going to take some doing.

     

    Just look at the 50 baht airport tax for taxis. another example that isn't really needed but someone would be losing a lot of money.

    2003? That old story was around in the '80s when they used to switch traffic direction on Sukhumvit and Petchburi almost by the month.

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