I applied on 4 September 2022, three days after the LTR program was announced. The only hiccup I had was that I had to run to Hong Kong to renew my Permanent Residency there while Thai immigration was processing my BOI-approved LTR application. Immigration then canceled my application because I was abroad (for a total of 18 hours, as it happened). Once I got the BOI involved again, they sorted it all out very quickly. Yes, it was the usual bureaucratic hassle, but it sure beats doing the annual Chaeng Wattana shuffle.