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The UK is embarking on an ambitious plan to accelerate research into mRNA cancer vaccines, with German pharmaceutical company BioNTech. Following the success of Covid vaccines using the same messenger-ribonucleic-acid technology, scientists now want to conduct more trials in cancer patients. And they are hoping to provide this personalised type of treatment to about 10,000 patients by 2030.

California hit with record-breaking rain and flooding The Bay Area and northern California are facing an atmospheric river bringing heavy wind, rain and flooding. This comes the day after getting hit by a bomb cyclone.

NO amount of alcohol is safe, WHO experts warn Claims come in report by a team of World Health Organization researchers WHO estimates that excessive alcohol consumption kills 3million each year Critics slammed the message accusing the authors of 'demonising alcohol' No amount of alcohol is 'safe', experts have warned. World Health Organization (WHO) researchers accepted that drinking may provide some 'small' health benefits, such as a lowering the risk of heart disease and type 2 diabetes. But the team argued these are clearly outweighed by booze's adverse effects. Excessive alcohol consumption can permanently damage the liver and cause cancer, they warned.

The long-awaited Gladiator sequel will reportedly begin shooting in May with filming locations already selected for Ouarzazate, Morocco. The Sun reports that locations in the Moroccan city have been chosen for filming, with a source estimating the sequel could be 'ready' as early as 2024. While details of the story have remained closely guarded, the outlet reports the sequel may revolve around Roman Empress Lucilla's son Lucius Verus.

Putin tells Ukraine he is ready for peace talks - but only if Kyiv accepts 'new territorial realities' Putin told Turkey's President Erdogan he was open to peace dialogue with Kyiv However, Kremlin said this was only possible if Ukraine accepts that territories occupied by Moscow's armies since the invasion began on Feb. 24 as Russian Erdogan called for peace talks in the phone call with Putin, his office said

A new partnership between the satellite phone firm Iridium and chip giant Qualcomm will bring satellite connectivity to premium Android smartphones later in the year. It means that in places where there is no mobile coverage, handsets can connect with passing satellites to send and receive messages. Qualcomm's chips are found in many Android-powered smartphones. Apple announced a satellite feature for the iPhone 14 in September 2022. The service is currently only available for sending and receiving basic text messages in an emergency.

Online retail titan Amazon is cutting more than 18,000 jobs worldwide in the largest layoffs programme in its history as part of plans to slash costs. It is understood the job losses will include the UK and Europe, but the firm has not given details of how each country will be affected.

Tributes were paid to David Gold on Wednesday night after West Ham United’s joint chairman died, aged 86. Players wore black armbands during the club’s Premier League game at Leeds United, while a replica shirt bearing his name and a bouquet of flowers were placed on a seat in the Elland Road directors’ box.

He left here just after Christmas and we won’t be spending another one [together] again, it’s painful,' Sean's father told ITV News London A personal trainer from West London was shot twelve times in the head and chest while on holiday with a friend in Jamaica, his distraught family claims. Speaking to ITV News London, the father of Sean Patterson said his son was killed days after arriving in the Caribbean outside a guest house in St James.

The New Year is a great time to ensure that all your devices are operating on the most up-to-date software and that your privacy is being protected. With all this in mind, here's a step-by-step guide to help you with these top priorities.

Android users urged to check phone settings now as millions set for major update A number of Google Pixel devices are eligible to receive their first update for 2023, which includes fixes for camera, Bluetooth and display issues as well as spatial audio suppo

The Russian military's top brass is under increasing scrutiny as more details emerge of how at least 89 Russian soldiers, and possibly many more, were killed in a Ukrainian artillery attack on a single building. The scene last weekend in the Russian-held eastern Ukrainian town of Makiivka, where the soldiers were temporarily stationed, appears to have been a recipe for disaster.

Australia will spend more than $1bn on new naval missiles and acquiring a US rocket artillery system used by the Ukrainian military. The defence industry minister, Pat Conroy, said the acquisition of 20 high mobility artillery rocket systems (Himars) including launchers, missiles and training rockets, from the US defence contractor Lockheed Martin was the “largest expansion of army strike capability in living memory”, reflecting the need to deter threats in a time of “strategic uncertainty”.

Sales of electric vehicles have reached record levels in the UK, although supply chain disruption drove total sales of new cars to their lowest level in 30 years. Just more than 1.6m new cars were sold in the UK last year, a 2% fall from 2021, and the lowest level since 1992, according to the annual sales snapshot from the Society of Motor Manufacturers and Traders (SMMT).

The two stars of the film Romeo and Juliet, released in 1968, are suing Paramount Pictures for more than $500 million (over £414 million) over a nude scene in the film shot when they were teenagers. Olivia Hussey, who played Juliet when she was 15 and is now 71, and Leonard Whiting, who was 16 when he played Romeo and is now 72, filed the suit on Tuesday in Los Angeles County Superior Court alleging sexual abuse, sexual harassment and fraud. Full story