yep. but most importantly is how the cannabis is used to infuse the edible. most don't infuse properly and with the wrong methods. the old butter and weed method is not reliable at all and wont be able to give anything close to an accurate dose when compared to using extracts in the edible.
also the quality of cannabis used either to infuse or to make the extract is vital.
s in s out is as simple as i can put it.