Ibuprofen, naproxen, and diclofenac (all NSAIDs) do not directly affect the adrenal system, but they can interact with it in indirect or secondary ways, especially with long-term use or in people with certain conditions.
Do NSAIDs affect adrenal hormone production directly?
No — NSAIDs do not directly suppress or stimulate adrenal hormone production. They don’t act on the hypothalamic-pituitary-adrenal (HPA) axis like corticosteroids do.
Maybe you are thinking of corticosteroids.
Are you a Seventh Day Adventist or something?