onebir

6 hours ago, cmarshall said:

Why is the G strain so effective at dominating in the US, but can't seem to make any headway in China at the same period, since by May SARS-COV2 was effectively eradicated in China?  

Government measures etc were definitely a factor, but the bats this virus came from are endemic to SW China & (northern) SE Asia. Similar viruses may have crossed the species barrier recently enough (in evolutionary time) that the local populations have some adaptations that render them less susceptible.

Examples of similar adaptations: sickle cell anemia (confers some protection to malaria) and CCR5 Delta 32 (confers immunity to HIV, apparently a mutation that was selected for during the Black Death).

Can't say for sure, or how big an effect similar factors might be having on Covid-19, but I don't think their existence can be excluded yet.

7 hours ago, gunderhill said:

That said the ridiculous UK  house prices today create a huge financial burden on youngsters who already to get a decent  education (which was free right though to university  when I was schooled) creates    debt even before you become employed.

Housing prices & higher-ed fees: both huge impediments to social mobility, already hugely divisive & only set to worsen.

On 2/12/2021 at 11:20 AM, Proboscis said:

Are we surprised that such a large number of Brits are in bad shape? THe average British city does not make room for bicycles.

The average brit weather doesn't exactly suit bicycles either...

37 minutes ago, Mister Fixit said:

1)  I suppose I use between 4 and 6 tablets a month, more likely nearer the 4.  It's a bit awkward at the moment because we have my wife's dim 23 year old niece staying which is off-putting anyway but that's not the issue.
That's not excessive use so no need to reduce intake and if I took a break I would not be able to have sex.  Hence, there is no 'chronic use'  to be concerned about in my view.

2) No.

And I thought it was nitrous oxide which was involved in vaso-dilation in an erection, not nitrous dioxide.  I am no biochemist though so I could well be wrong but I think not.

1) I'd also be surprised if once every 5-7 days wasn't enough to give receptors or whatever time to recover.

2) Apparently I'm no biochemist either ???? But there are supplements and herbs that increase NO levels and might be worth a try. (Like arginine, which I found on Lazada for about $15/100g)

Quote

Phase 2 - June to September: would involve the setting up of an exclusive travel area or "seal route" in which tourists could move around while doing Area Quarantine for 10 days.

Let's clap for that! Arf arf!

7 hours ago, Mister Fixit said:

At first I used half a 100 mg tablet of real Viagra, then changed to Kamagra as it was cheaper.  Over time, I had to increase to a full 100mg tablet.  Then I tried the Thai GPO version, Sidegra, but that really was not as good at all so I reverted to Kamagra.

1) How often do you use these drugs; have you tried using them less often &/taking a break from them?

'Chronic' use of many drugs causes downregulation of the relevant receptors, weakening their effectiveness. Often the only fix is to stop using them/use them less for a while; this can allow the receptors to recover. (Occasionally there's another drug that prevents receptor downregulation, but that's a bit of a needle in a haystack.)

2) Have you (or your doc) reviewed their metabolic pathway of silfafenil?

IIRC it involves increasing NO2 synthesis, and that needs some inputs (amino acids?). Perhaps your intake/reserves of these inputs are low.

11 minutes ago, rcuthbert said:

TRT has at least 2 pitfalls. It shuts down your HPTA (hypothalamic-pituitary-gonadal axis*) - which stops (In layman's terms) the testes production of sperm and testosterone - so your nuts shrink.

The OP had a pituitary adenoma, could his HPTA return to normal functioning?

6 hours ago, Sticky Rice Balls said:

Ive tinkered with this one ...good for a quickie but not long time ????

TBA: https://www.fda.gov/drugs/medication-health-fraud/public-notification-grakcu-capsule-contains-hidden-drug-ingredients

(Same warning from Aus FDA; IDK if the verion(s) sold in Thailand also have this problem.)

Looks like this is what they're supposed to contain:

- Cordyceps sinensis
- Goryanka grandiflora (aka epimedium/'horny goat weed')
- Dodder (aka Cuscuta)
- Wild Yam
- Schisandra chinensis
- Ziziphus jujube
- Lycium chinensis

(ie pretty standard TCM herbs.)

On 3/12/2021 at 5:42 PM, BangkokReady said:

As we have seen already, they simply say "men are the problem".  Such people don't want to fix anything, otherwise they wouldn't lump all men in together.  The would focus on violence, rather than males.

There is the notion of 'toxic masculinity', but 'toxic' is apparently a nuance too far for most...

On 3/12/2021 at 5:06 PM, KhaoYai said:

I have to say though that I'd have been happy to have either the AZ or Pfizer vaccines.

I won't trust the lipid nanoarticle vector platforms until they've been in the wild for about 2 years, just in case they turn out to cause auto-immune disease. (I believe there were issues with that in some of their animal trials.)

Adenovirus vector platforms (in AZ & Sputnik) have at least been around a lot longer.

12 hours ago, JonnyF said:

Yes I saw that. She wants a curfew on men from 6pm.

However, she also supports gender self identification so I think I see a way around this for any women with a penis who fancy a quick pint in the evening ????.

'"Grow some!" they said. So I did."

On 3/8/2021 at 3:02 AM, webfact said:

In the latest accusations, the Wall Street Journal reported on Saturday that a former aide, Ana Liss, said Cuomo in 2014 sometimes greeted her with a hug and kisses on both cheeks, called her "sweetheart," kissed her hand and asked her if she had a boyfriend.

I hope they never holiday in southern Europe, where thousands of huggy cheek kissing sexual harassments* go unremarked on a daily basis.

OTOH, how are politicians getting elected if they're insensitive to making people uncomfortable? Can't be a vote-winner...

*meso-agressions?

13 hours ago, webfact said:

Anutin Charnvirakul, DPM and health minister, who favors 7 day area quarantine for  those foreigners who have received two doses of vaccine and ten days (not confined to hotel rooms) for those that haven't been jabbed. 

30% less quarantine when being vaccinated probably cuts transmission risk by >95%. Way to go!

3 hours ago, Bkk Brian said:

Too many clots spoils the broth

Too many clots spoil the tom lueat mu - TIT!

World-first Digital Yacht Quarantine Hub

14 minutes ago, lkv said:

Prayuth was scheduled later on today for a jab of this, he'd better take some Aspirin before. ????

Warfarin?

During US Celebrity Apprentice, 2008

Quote

Morgan was called "ruthless, arrogant, evil and obnoxious" by Trump in the final.

So he can't be all bad.

25 minutes ago, ThaiVisaCentre said:

???? not sure about that one

Just kidding ????

38 minutes ago, ThaiVisaCentre said:

Here is a list of 8 hotels with a washing machine, and a balcony.

https://asq.in.th/?selectedFeaturesFilter=Washing Machine_Balcony

Now suppose we want the washing machine ON the balcony...

What I want to know is why anyone would bother DDOSing this site.

Unless it was just an extortion attempt, sounds like someone could be p***ed of with (apparently rather harmless?) TVF...