Manidipine and Cesoline - Any Have Experience ?

[Speedo1968]

For HBP - causing multiple TIA's and Strokes I was prescribed Cardeloc by a specialist in Khon Kaen.   This doctor has been treating me since 2012.

I already had a very low heart rate for many years which had not caused me any problems.  It was / is consistently within a small range and peaking only by one or two points after walking or swimming etc.

Following another stroke ( with complications ) in June 2017 I was prescribed Manidipine but it did not agree with me.

A very bad TIA last week and hospitalised in my local hospital I was prescribed Manidipine and Cesoline.

 

Has anyone had experience of using either of these medications as I understand they are not accepted in some countries ?

[Winstein]

For HBP - causing multiple TIA's and Strokes I was prescribed Cardeloc by a specialist in Khon Kaen.   This doctor has been treating me since 2012.
I already had a very low heart rate for many years which had not caused me any problems.  It was / is consistently within a small range and peaking only by one or two points after walking or swimming etc.
Following another stroke ( with complications ) in June 2017 I was prescribed Manidipine but it did not agree with me.
A very bad TIA last week and hospitalised in my local hospital I was prescribed Manidipine and Cesoline.
 
Has anyone had experience of using either of these medications as I understand they are not accepted in some countries ?

Sorry I not answering your original quistion.

But why not have pace maker? Think helps if it's steady and no surprises ""

Have an onkel he was down to 35 beat a minute (he is a crazy exercising) they still put in pace maker to push up the beat. And he was not sick in any way so very strange story[emoji848]

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[Sheryl]

51 minutes ago, Winstein said:

Sorry I not answering your original quistion.

But why not have pace maker? ...
 

Because the low heart rate is nto causing him any problems.

 

 

[Sheryl]

Manidipine is a calcium channel blocker, same type of drug as amlodipine, and has been used for many years foir treating hypertension.

 

Cesoline is hydralazine, a very old drug not so widely used these days. It is  a vasodilator and very potent. 

 

I am not aware if any particular controversy regarding either drug nor of either being not approved in any country, but as mentioned the hydralazine is very potent and not used as first line treatment for hypertension, usually used more short term when BP is dangerously high and needs to come down fast, may also be added to other drug regimen for long term use in people who just don't respond to other meds.

 

Of course, like all drugs, these have side effects. The hydralazine (Cesoline) is especially potent..and calcium channel blockers cause leg swelling in many people.

 

You are on an unusual combo of meds but without knowing what other drugs were tried I can't really comment. Perhaps your BP is proving hard to control? How high is it? Have many other drugs been tried and failed?

 

I am also very puzzled by your statement that you were previously on Cardeloc for hypertension. this is a beta blocker and, except in people with certain types of heart conditions, no longer recommended in management of hypertension. It also slows the heart rate and would nto usually be advised for someone already with a low heart rate. Are you sure the low heart rate was before starting Cardeloc? And not something that you had after you were on it?

 

In short both what you were on before and what you are on now for high BP is unusual but without knowing the full history I cannot say if there is reason for it. How high is your BP? What other meds have been tried? What other medical problems do you have?

 

Are you also on something to reduce blood clotting (aspirin or anticoagulant)? As that is the mainstay of management to prevent TIAs.

[WeLubThailand]

Do you have any idea who is answering your medical questions and how qualified they are in that specific field? At the end of the day, you will have to be responsible for your own health. See a qualified doctor.