Key Evidence That mRNA Vaccines Have Saved Lives:
1. Global Mortality Reduction Studies
• A 2022 study published in The Lancet Infectious Diseases estimated that mRNA and other COVID-19 vaccines prevented over 14.4 million deaths in 185 countries in the first year of their rollout (December 2020–December 2021).
• Source: Watson et al., 2022, The Lancet Infectious Diseases
2. Hospitalization and Severe Disease Prevention
• Real-world data from the CDC and UK Health Security Agency consistently show that mRNA vaccines significantly reduced severe COVID-19 cases, hospitalizations, and deaths, particularly among older adults and high-risk populations.
• Example: A study from the U.S. CDC found that mRNA vaccines were 91% effective at preventing hospitalization among fully vaccinated individuals.
• Source: CDC, NEJM, 2021
3. Comparison of Excess Mortality in Vaccinated vs. Unvaccinated Populations
• Excess mortality (the number of deaths above expected levels) was dramatically lower in countries and populations with high mRNA vaccine uptake compared to those with lower vaccination rates.
• Example: Data from the UK Office for National Statistics (ONS) showed that COVID-19 mortality rates were significantly higher among unvaccinated individuals.
4. Real-World Case Studies (e.g., U.S., UK, Israel)
• Israel was one of the first countries to roll out mRNA vaccines at scale. Research showed that COVID-19 deaths dropped sharply following the vaccine rollout, particularly among elderly and high-risk groups.
• The U.S. and UK saw hospital ICU admissions decline dramatically after mRNA vaccines were widely distributed in 2021.
Scientific Consensus & Expert Reviews
• Leading health organizations like the WHO, CDC, FDA, EMA (European Medicines Agency), and UK MHRA confirm that mRNA vaccines saved millions of lives and helped control the pandemic.
• Independent reviews from institutions like Johns Hopkins, Harvard, Oxford, and Imperial College London also affirm the effectiveness and life-saving impact of mRNA vaccines.