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Anyone offer thyroid testing by LC-MSMS?


Monomial

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There is a growing body of evidence that thyroid panels via the inexpensive CMIA (chemiluminescent microparticle immunoassay) tests common in Thailand (and really everywhere) are actually not very reliable when reporting Free T3/T4, often overestimating the numbers and indicating no cause for concern in cases where a problem might actually exist. The conjecture is that the LC-MSMS (liquid chromatography tandem mass spectrometry) process gives a much more accurate result. [*1]   A brief check on the internet though hasn't yielded any information as to whether there is anyone in Thailand who offers thyroid panels using this method.  Does anyone know if there is a hospital or lab in Bangkok that can run the more accurate analysis?

 

[*1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113291/

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I doubt it but do not really know. It is certainly not what any of them do for routine tests. Possible that major teaching hospital like Siriraj has capacity to do LC-MSMS

 

Note that due to cost and complexity of the test it is not recommended to do LC-MSMS routinely, only in cases where clinical symptoms persist despite treatment with levothyroxine,

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