Aside from Project 2025, if in four years there is no two-state solution in sight and the situation in the Occupied Territories is worse, Michigan would be a serious vulnerability with a pro-Israel Jew leading the Democratic ticket.
As for the 2000 election, Gore looked pretty healthy, but proposing a strident Orthodox Jew as VP was not sensible with the failure of Camp David and Ariel Sharon's subsequent provocation on the Temple Mount a few months before the election. You may remember that the pivotal state was Florida where Gore lost by 529 votes while Ralph Nader, a Lebanese-American, got 100,000 votes in that state. That seems to be quite a high number for the Greens.
Harris in any case was damaged goods by being Biden's VP, and she failed to show how she would do differently and better than Biden. She did not come off as authentic to me, rather insensitive to the concerns of the people. Her resounding loss should have been no surprise.