Dublin-Boston Scoring System Helps Predict Which COVID-19 Patients Will Develop Severe Infection

Dublin-Boston Scoring System Helps Predict Which COVID-19 Patients Will Develop Severe Infection

by Global Biodefense Staff  October 14, 2020, 3:29 pm

A new COVID-19 patient assessment system, called the Dublin-Boston score, is designed to enable clinicians to make more informed decisions when identifying patients who may benefit from therapies, such as steroids, and admission to intensive care units.

The blood test works by measuring the levels of two molecules that send messages to the body’s immune system and control inflammation. One of these molecules, interleukin (IL)-6, is pro-inflammatory, and a different one, called IL-10, is anti-inflammatory. The levels of both are altered in severe Covid-19 patients.

Based on the changes in the ratio of these two molecules over time, the researchers developed a point system where each 1-point increase was associated with a 5.6 times increased odds for a more severe outcome.

Read full article: https://globalbiodefense.com/2020/10/14/dublin-boston-scoring-system-helps-predict-which-covid-19-patients-will-develop-severe-infection/

Scientific study cited in the news article:

A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19