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Natural Experiment Links Shingles Vaccine To 20% Reduced Risk of Dementia


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Researchers who tracked cases of dementia in Welsh adults have uncovered the strongest evidence yet that the shingles vaccination reduces the risk of developing the devastating brain disease.

Health records of more than 280,000 older adults revealed that those who received a largely discontinued shingles vaccine called Zostavax were 20% less likely to be diagnosed with dementia over the next seven years than those who went without.

 

Pascal Geldsetzer, at Stanford University, said: “For the first time we are able to say much more confidently that the shingles vaccine causes a reduction in dementia risk.

https://www.theguardian.com/society/2025/apr/02/study-finds-strongest-evidence-yet-that-shingles-vaccine-helps-cut-dementia-risk

 

Here's a link to the original research published in Nature.

https://www.nature.com/articles/s41586-025-08800-x

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