If Statins increase atherosclerosis,..

[cysampan]

If Statins increase atherosclerosis considerably, and you already have it. - Why on earth would my doctor have prescribed them? Wouldn't I be better off eliminating them and relying on diet alone? My cholesterol ratios are now way low.

[DogNo1]

Refer to spacedoc.com for exhaustive information on heart disease medicine.

[FracturedRabbit]

https://www.ncbi.nlm.nih.gov/pubmed/31175783/


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[hanuman2543]

Interesting read:

https://www.sciencedirect.com/science/article/pii/S0167527318347417?fbclid=IwAR2gqPyu-3WminbhjyIYhIJZkwEQtsbpL2vKGqRbX--ApQMB7x1VelQg3j4

[FracturedRabbit]

Not sure if statins actually increase atherosclerosis, but there is not much science that I have found that indicates that it reduces it. For those that have actually had a cardiac event, statins do seem to reduce the risk of a follow up event, but that may be more due to their anti-inflammatory properties rather than their stated goal of lowering LDL.

 

I found out I had atherosclerosis two years ago, with a 50% blockage in one artery that resulted in feelings of faintness. Doctor prescribed beta blockers to slow my heart and stop the faint feeling, which they did, and statins to get my LDL down to 70 which he said gave me a 5% chance of slowing the disease; although he could not explain how. He also never asked me what I ate....

 

I threw the statins away because they made me feel terrible and started reading. I discovered that LDL, the bad cholesterol, is not cholesterol and it is not bad. Indeed as you get older your all cause mortality risk is lower if you have high LDL. Oxidised LDL may indeed be associated with arterial damage; but if you are metabolically healthy then your LDL is not going to oxidise. LDL has a cell repair function. There are no studies that correlate high LDL with atherosclerosis; but there is strong correlation between low HDL and/or high triglycerides and atherosclerosis; which is why the Trig/HDL ratio is such an important marker; should be less than 2. With lifestyle changes my HDL is now 94 and my trigs are 58, giving a ratio of 0.6. Three months ago I was feeling so healthy I tried stopping the beta blockers and felt fine, and my heart, which used to start fluttering at 138bpm does not complain at 155bpm. I will have a CAC scan in a couple of years and my goal is to substantially reduce the plaque.

But to answer your question, your doctor prescribed because they are highly profitable and there is a massive industry and PR campaign to keep them relevant.

[cysampan]

Good lord.

[Sheryl]

Statins do not increase athersclorosis, where did you get that idea from?

 

They do not significantly shrink them in size, that is true, but that is quite different from increasing them, and it is thought they may have other effects on atherosclerotic plaques in ways that reduce the associated risks. in particular it is thought they render athersclerotic plaques less likely to rupture.

 

See

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599025/

[ivor bigun]

Statins do not increase athersclorosis, where did you get that idea from?
 
They do not significantly shrink them in size, that is true, but that is quite different from increasing them, and it is thought they may have other effects on atherosclerotic plaques in ways that reduce the associated risks. in particular it is thought they render athersclerotic plaques less likely to rupture.
 
See
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599025/

Had a by pass 33 years ago and have taken them ever since,anyone who says they are bad is mad.

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[cysampan]

High dose and long-term statin therapy accelerate coronary artery calcification

Article in International Journal of Cardiology 184(1):581-586 · February 2015 with 245 Reads

 

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Statin Medication Enhances Progression of Coronary Artery Calcification

Journal of the American College of Cardiology

Volume 68, Issue 19, November 2016DOI: 10.1016/j.jacc.2016.08.040

 

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Progression of Vascular Calcification Is Increased With Statin Use in the Veterans Affairs Diabetes Trial (VADT)

Diabetes Care 2012 Nov; 35(11): 2390-2392.https://doi.org/10.2337/dc12-0464

 

etc

 

 

 

[elliss]

 

  I thought medicine, is/was a Science.