Interesting article on development of mRNA vaccines: The tangled history of mRNA vaccines

[cdemundo]

Interesting article on development of  mRNA vaccines: The tangled history of mRNA vaccines

 

from Nature

 

https://www.nature.com/articles/d41586-021-02483-w?utm_source=Nature+Briefing&utm_campaign=41794890cb-briefing-dy-20210914&utm_medium=email&utm_term=0_c9dfd39373-41794890cb-44956685

[rabas]

Excellent article covering the full story back to Robert Malone in 1987.

 

It includes Jason McLellan, whose patented custom spike design is behind Moderna's and Pfizer's high effectiveness. It forces the spike into a preferred configuration that produces much higher immunity. This is not possible with inactivated virus vaccines. The design is called 2P. They now have a newer design called HexaPro.

 

The tiny tweak behind COVID-19 vaccines

[Virt]

Nice article with a lot of interesting info.

 

When the Nobel prize is given to some of these pioneers, it will be interesting to see how the anti vax brigade will react.

[Scott]

I had read some stuff quite some time ago about Katalin Karikó.  She was actually demoted from her University position for continuing her work in the field of mRNA.

 

[friendofthai]

7 hours ago, Virt said:

When the Nobel prize is given to some of these pioneers, it will be interesting to see how the anti vax brigade will react.

Not sure about how they will react but I am sure that the Chinese guys will be laughing for sure. Prizes and awards are appropriate in case of victory. Such as China's victory over COVID. But they look very funny in case of huge growing number of new COVID cases every day.

[placeholder]

4 hours ago, friendofthai said:

Not sure about how they will react but I am sure that the Chinese guys will be laughing for sure. Prizes and awards are appropriate in case of victory. Such as China's victory over COVID. But they look very funny in case of huge growing number of new COVID cases every day.

 China's success predates vaccines and has nothing to do with them. Rather,  right from the start China instituted a very strict program of contact tracing and quarantining. China has a huge advantage over most other nations because it's an Orwellian police state.

[friendofthai]

33 minutes ago, placeholder said:

 China's success predates vaccines and has nothing to do with them. Rather,  right from the start China instituted a very strict program of contact tracing and quarantining. China has a huge advantage over most other nations because it's an Orwellian police state.

But you definitely see the success. It is undeniable. Anyone can easily see it without the need for a PhD in biology. In case of mRNA vaccines, the success is obvious only for those who stay inside the western Orwellian informational "freedom" state. Other people see that this is just another way of making vaccines with similar efficiency but difficult to store.
 

[placeholder]

14 minutes ago, friendofthai said:

But you definitely see the success. It is undeniable. Anyone can easily see it without the need for a PhD in biology. In case of mRNA vaccines, the success is obvious only for those who stay inside the western Orwellian informational "freedom" state. Other people see that this is just another way of making vaccines with similar efficiency but difficult to store.
 

 

Brazil has long used Sinovac's vaccine thanks to the pionering work of the prestigious Butantan Institute. Now there's this:

 

Brazil Moves Away From Chinese Covid-19 Vaccine
Brazil, a major buyer of China’s CoronaVac shot and a poster child for Beijing’s efforts at vaccine diplomacy, is making a speedy retreat from the Covid-19 vaccine as concerns grow over its efficacy against the Delta variant and other vaccines become more readily available.

Brazil’s federal government has halted negotiations over additional doses of Sinovac’s vaccine, CoronaVac, spokespeople for the government and its local producer, the Butantan Institute, told The Wall Street Journal. The government has also said it won’t recommend use of CoronaVac for a third booster shot.

https://www.wsj.com/articles/brazil-moves-away-from-chinese-covid-19-vaccine-11631368138

[Scott]

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