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356
An Idiots Guide to the Retirement Extension process at Samui Immigration Office
Some people believe they deliberately make it difficult in order to motivate applicants to use an agent, which can benefit them. Either that or they just enjoy making farangs sweat. Or both. -
98
House Approves Sanctions on ICC Over Netanyahu Arrest Warrant
That's nice, and every Gazan owns what they did on October 7: The murders, the rapes, the atrocities , the hostage taking. According to Shariah law, they will pay with their lives. Such is the law that they have chosen to live by. -
48
Evidence of Covid19 vaccine shedding
Before mRNA vaccines, such as the Pfizer-BioNTech and Moderna COVID-19 vaccines, were approved for emergency or full use, they underwent several rigorous stages of testing to assess safety and efficacy. Here’s an outline of the process: 1. Preclinical Testing (Lab and Animal Studies) • Objective: To assess the safety, immune response, and potential efficacy of the vaccine. • Process: • Animal studies: Typically conducted in mice, rats, and non-human primates to evaluate whether the vaccine induces the desired immune response and does not cause harmful effects. • The mRNA technology used in the COVID-19 vaccines had been previously studied in labs for other diseases (e.g., Zika, flu, cancer), but the COVID-19 vaccines were tested in animals before moving to human trials. • Outcome: Encouraging results were obtained in animals, showing that the mRNA vaccines were effective at generating an immune response. 2. Phase 1 Clinical Trials (Initial Human Trials) • Objective: To evaluate the safety and dosage of the vaccine. • Process: • Participants: A small group (often 20-100) of healthy volunteers. • Testing: The focus was on safety, the immune response, and determining the appropriate dosage for further trials. • Outcomes: This phase helped identify any immediate, severe side effects (e.g., allergic reactions) and the optimal dose that induces a good immune response. • Duration: Typically 1-2 months. 3. Phase 2 Clinical Trials (Expanded Human Trials) • Objective: To further assess safety, side effects, and immune response in a larger group of participants. • Process: • Participants: Hundreds of volunteers, including those from various age groups and risk categories. • Testing: Vaccine doses were refined, and participants were monitored for side effects, immune responses, and any potential efficacy signals. • Outcomes: This phase confirmed the safety and immune response induced by the vaccine. • Duration: Usually several months. 4. Phase 3 Clinical Trials (Large-Scale Human Trials) • Objective: To assess the vaccine’s efficacy and safety in a much larger population. • Process: • Participants: Thousands of volunteers (often over 30,000), including people from a wide range of demographics (e.g., elderly, people with underlying health conditions). • Testing: This phase measured how well the vaccine protected against infection (or severe illness) and assessed side effects across a large group. • Outcome: • Efficacy: The mRNA vaccines showed high efficacy in preventing symptomatic COVID-19 (around 94-95% in early results for Pfizer-BioNTech and Moderna). • Safety: Serious side effects were rare, and the vaccines generally had side effects similar to those of other vaccines (e.g., soreness at the injection site, fatigue, mild fever). • Duration: Typically lasted several months to a year. 5. Emergency Use Authorization (EUA) / Approval • After Phase 3 trials, Pfizer-BioNTech and Moderna submitted data to the U.S. Food and Drug Administration (FDA) and other regulatory bodies (e.g., the European Medicines Agency or EMA) for Emergency Use Authorization (EUA). • Regulatory agencies conducted a thorough review of all data, including: • Efficacy data showing that the vaccine effectively prevented severe COVID-19 illness. • Safety data showing that the vaccines had a favorable risk-benefit profile. • After the review, both vaccines were granted EUA by the FDA in December 2020, allowing them to be administered to the public while ongoing monitoring continued. 6. Post-Approval Monitoring (Phase 4) • Objective: To continue monitoring the vaccine’s long-term safety and effectiveness in the general population. • Process: • Ongoing surveillance systems like the Vaccine Adverse Event Reporting System (VAERS) and V-safe were used to monitor adverse events, including rare or long-term side effects. • The EUA was later converted to full approval (for Pfizer-BioNTech in August 2021) based on continued safety and efficacy data. Summary: • Preclinical studies and clinical trials (Phases 1-3) assessed safety, immune response, and efficacy. • The mRNA vaccines were subjected to more rigorous testing than some other vaccine types due to the novel technology, but they followed standard protocols used for any vaccine approval. • Post-approval monitoring continues to ensure safety in the wider population. Hardly......"not tested at all" -
356
An Idiots Guide to the Retirement Extension process at Samui Immigration Office
Have you used the online-system for extension of stay? -
985
Revenue Department boss calls on tax residents in Thailand to file 2024 returns by March 31
On the UK Gov website there is a long list of Government pensions listed in alphabetical order ( I think ) The First on the list is Armed Forces Pensions and on it goes. A link to it has already been posted in one of the threads. All these Pensions ( above the 12570 UK threshold ) are taxed at source. A UK Citizen will pay tax on this, in the UK, until the day they die. A Dual National, can change tax regimes, only if they return to their Country of origin. -
16
Bangkok Taxi Driver Slashes Passenger's Face in Violent Attack
Arguing with a taxi driver probably isn't the smartest thing to do. I wonder what this was all about? The amount of the fare? Usually, even if they quote you what they think is a rip off rate, it doesn't seem like such a big deal, and it's probably better just to say OK that to wait around trying to find another cab with a lower rate.
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