Steroid dexamethasone reduces deaths among patients with severe COVID-19 - trial shows

 

FILE PHOTO: A 3D-printed coronavirus model is seen in front of the words coronavirus disease (Covid-19) on display in this illustration taken March 25, 2020. REUTERS/Dado Ruvic/Illustration/File Photo

 

LONDON (Reuters) - Giving low doses of the generic steroid drug dexamethasone to patients admitted to hospital with COVID-19 reduced death rates by around a third among those with the most severe cases of infection, trial data showed on Tuesday.

 

The results, described as a "major breakthrough" by scientists leading the UK-led clinical trial known as RECOVERY, suggest the drug should immediately become standard care in patients treated in hospital with the pandemic disease, the researchers said.

 

"This is a result that shows that if patients who have COVID-19 and are on ventilators or are on oxygen are given dexamethasone, it will save lives, and it will do so at a remarkably low cost," said Martin Landray, an Oxford University professor who is co-leading the trial.

 

His co-lead investigator, Peter Horby, said dexamethasone - a generic steroid widely used in other diseases to reduce inflammation - is "the only drug that's so far shown to reduce mortality - and it reduces it significantly."

 

"It is a major breakthrough," he said.

 

There are currently no approved treatments or vaccines for COVID-19, the illness caused by the new coronavirus which has killed more than 431,000 globally.

 

-- © Copyright Reuters 2020-06-16

 

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Great news! I hope Trump will promote this new drug so that more people can be helped.

Sounds good. Tomorrow we'll probably get a contradictory report saying it doesn't work

10 minutes ago, Crazy Alex said:

Great news! I hope Trump will promote this new drug so that more people can be helped.

Swallow it down with bleach ?

2 minutes ago, spiekerjozef said:

Swallow it down with bleach ?

No I think the bleach is a suppository and the steroid is orally lol anyway it’s a hopefull sign they are making progress on treatments let’s hope this one pans out stay safe and healthy all!!

8 minutes ago, spiekerjozef said:

Swallow it down with bleach ?

No. Who would make such a recommendation?

49 minutes ago, Crazy Alex said:

Great news! I hope Trump will promote this new drug so that more people can be helped.

Because otherwise doctors might be reluctant to give it to their patients? Because doctors are more likely to listen to Trump than to Anthony Fauci? Or to the Surgeon General? I knew Trump was chief executive of the USA. I didn't know that he was also Chief Medical Officer.

4 minutes ago, johnpetersen said:

Because otherwise doctors might be reluctant to give it to their patients? Because doctors are more likely to listen to Trump than to Anthony Fauci? Or to the Surgeon General? I knew Trump was chief executive of the USA. I didn't know that he was also Chief Medical Officer.

Hey, who needs professional medical advice when you have a self proclaimed stable genius guiding everyone?

An off topic trolling post has been removed. 

Yes great news on this, cheap as chips drug, lets hope more treatments like this are discovered.

 

Had the drug had been used to treat patients in the UK from the start of the pandemic, up to 5,000 lives could have been saved, researchers say. "There is a clear, clear benefit. The treatment is up to 10 days of dexamethasone and it costs about £5 per patient. So essentially it costs £35 to save a life. This is a drug that is globally available."

 

https://www.bbc.com/news/health-53061281

41 minutes ago, johnpetersen said:

Because otherwise doctors might be reluctant to give it to their patients? Because doctors are more likely to listen to Trump than to Anthony Fauci? Or to the Surgeon General? I knew Trump was chief executive of the USA. I didn't know that he was also Chief Medical Officer.

Wow, interesting questions you ask just because I hope Trump promotes a drug that helps people. Who has ever said Trump was any sort of medical officer? I simply hope more Americans get effective treatment. Why does it seem to upset you so much?

36 minutes ago, samran said:

Hey, who needs professional medical advice when you have a self proclaimed stable genius guiding everyone?

People will always need professional medical advice.

45 minutes ago, Crazy Alex said:

Wow, interesting questions you ask just because I hope Trump promotes a drug that helps people. Who has ever said Trump was any sort of medical officer? I simply hope more Americans get effective treatment. Why does it seem to upset you so much?

Because it's odd that it's hope for Trump's recommendation that is your immediate response to this situation and not the recommendation of Fauci or similarly eminent and qualified persons whose opinions will actually carry weight in the medical community.

1 hour ago, johnpetersen said:

Because it's odd that it's hope for Trump's recommendation that is your immediate response to this situation and not the recommendation of Fauci or similarly eminent and qualified persons whose opinions will actually carry weight in the medical community.

Given how wrong Fauci has been on everything, I don't see him with much credibility at all.

don't you love doctors playing with patients like it were guinea pigs, and the winner will get the nobel price ...

 

a bit like nazi germany, but nah, people forgot about that

 

low vitamin D levels, low immunity, 1 baht a day worth of vitamin D could PREVENT most cases

'trial data showed'

But zero trial data presented and clearly not a clinical-based trial. Fundamentally, so-called data is just antedotal information, much like what we heard about alleged effectiveness of hydoxychloroquine (now proven ineffective at best).

14 hours ago, Crazy Alex said:

Great news! I hope Trump will promote this new drug so that more people can be helped.

Only after he first bought shares in the companies who produced it. 

WHO welcomes preliminary results about dexamethasone use in treating critically ill COVID-19 patients

 

“This is the first treatment to be shown to reduce mortality in patients with COVID-19 requiring oxygen or ventilator support,”

 

https://www.who.int/news-room/detail/16-06-2020-who-welcomes-preliminary-results-about-dexamethasone-use-in-treating-critically-ill-covid-19-patients

48 minutes ago, Srikcir said:

'trial data showed'

But zero trial data presented and clearly not a clinical-based trial. Fundamentally, so-called data is just antedotal information, much like what we heard about alleged effectiveness of hydoxychloroquine (now proven ineffective at best).

Really?

"The results, described as a "major breakthrough" by scientists leading the UK-led clinical trial known as RECOVERY, suggest the drug should immediately become standard care in patients treated in hospital with the pandemic disease, the researchers said."

11 hours ago, Crazy Alex said:

Given how wrong Fauci has been on everything, I don't see him with much credibility at all.

and you believe everything that absolute lunatic Trump says?  As for Fauci, he was right more often than not, and Trump just lies every time he opens his mouth.

6 hours ago, Srikcir said:

'trial data showed'

But zero trial data presented and clearly not a clinical-based trial. Fundamentally, so-called data is just antedotal information, much like what we heard about alleged effectiveness of hydoxychloroquine (now proven ineffective at best).

Isn't the jury still out on hydroxychloroquine since the Lancet article disputing its efficacy in late-stage COVID cases was discredited?

 

There appears to be a good case against using ventilation, and intubation in particular, in elderly patients, as it may kill more than it saves.

 

Studies in China, the United Kingdom and Seattle found mortality rates as high as 90% among patients on ventilators.

 

The UK leading the way again. When the going gets tough it's easy to separate the wheat from the chaff.

 

No doubt the Brit haters and the self loathing, hand wringing UK liberals will be along shortly to try and pour cold water on this but it's great news for everyone around the world. Well done to the UK led team ????.

 

 

22 hours ago, Crazy Alex said:

Great news! I hope Trump will promote this new drug so that more people can be helped.

It’s a widely available Generic, there’s no money in promoting it.

2 hours ago, JonnyF said:

The UK leading the way again. When the going gets tough it's easy to separate the wheat from the chaff.

 

No doubt the Brit haters and the self loathing, hand wringing UK liberals will be along shortly to try and pour cold water on this but it's great news for everyone around the world. Well done to the UK led team ????.

 

 

You’d have to have a pretty craven mind to think that anyone would have issues for this work and it’s outcome just because of their nationality....

14 hours ago, robblok said:

Only after he first bought shares in the companies who produced it. 

Why do you say that?

5 hours ago, Chomper Higgot said:

It’s a widely available Generic, there’s no money in promoting it.

You mean like hydroxychloroquine? Oops!

Edited June 17, 20206 yr by Crazy Alex

13 hours ago, TigerandDog said:

and you believe everything that absolute lunatic Trump says?  As for Fauci, he was right more often than not, and Trump just lies every time he opens his mouth.

Why do you think I believe everything Trump says? I don't believe everything ANYONE says, especially anti-Trump zealots.

7 hours ago, Crazy Alex said:

Why do you say that?

Because Trump is a guy that wants to make money out of everything. Shown by how he always expects something for what he does. If you still don't understand he is a low life then your beyond help. Anyway you credit your name as a die hard Trump follower. 

7 hours ago, Crazy Alex said:

You mean like hydroxychloroquine? Oops!

That was just a way for Trump to bring some positive news to hide all his failures. 

17 hours ago, samran said:

You’d have to have a pretty craven mind to think that anyone would have issues for this work and it’s outcome just because of their nationality....

Oh really?

 

I don't think some of the loony liberals would have issues with the UK doing great work on C-19, I know it. They're so guilt ridden and hateful towards their own country that they are terrified it could lead to national pride. ????.

 

Don't believe me?

 

https://www.express.co.uk/news/uk/1273335/oxford-coronavirus-vaccine-trial-begins-covid19-doctor-emily-cousens-political-correctness