Popular Post snoop1130 Posted November 11, 2020 Popular Post Share Posted November 11, 2020 Russia says its Sputnik V COVID-19 vaccine is 92% effective By Polina Ivanova A view shows vials with EpiVacCorona vaccine against the coronavirus disease (COVID-19), developed by the Novosibirsk Region based Vector state research institute under Rospotrebnadzor service, in this undated handout photo at an unknown location in Russia. Rospotrebnadzor Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing/Handout via REUTERS MOSCOW (Reuters) - Russia's Sputnik V vaccine is 92% effective at protecting people from COVID-19 according to interim trial results, the country's sovereign wealth fund said on Wednesday, as Moscow rushes to keep pace with Western drugmakers in the race for a shot. The initial results are only the second to be published from a late-stage human trial in the global effort to produce vaccines that could halt a pandemic that has killed more than 1.2 million people and ravaged the world economy. The results are based on data from the first 16,000 trial participants to receive both shots of the two-dose vaccine, the Russian Direct Investment Fund (RDIF), which has been backing its development and marketing it globally, said. "We are showing, based on the data, that we have a very effective vaccine," said RDIF head Kirill Dmitriev, adding that it was the sort of news that the vaccine's developers would talk about one day with their grandchildren. The analysis was conducted after 20 participants in the trial developed COVID-19 and examined how many had received the vaccine versus a placebo. That is significantly lower than the 94 infections in the trial of a vaccine being developed by Pfizer Inc and BioNTech. To confirm the efficacy rate, Pfizer said it would continue its trial until there were 164 COVID-19 cases. RDIF said the Russian trial would continue for six more months and data from the study will also be published in a leading international medical journal following a peer review. European stocks and U.S. stock futures extended their gains slightly after Russia's announcement. [MKTS/GLOB] ANOTHER BOOST Russia's announcement follows swiftly on from results posted on Monday by Pfizer and BioNTech, which said their shot was also more than 90% effective. The Russian results are another boost to other COVID-19 vaccines currently in development and are a proof of concept that the disease can be halted with vaccination. Experts said knowledge about the trial's design and protocol was sparse, making it difficult to interpret the figures released on Wednesday. Scientists have raised concerns about the speed at which Moscow has worked, giving regulatory go ahead for the shot and launching a mass vaccination programme before full trials to test its safety and efficacy had been completed. Russia registered its COVID-19 vaccine for public use in August, the first country to do so, though the approval came before the start of the large-scale trial in September. The so-called Phase III trial of the shot developed by the Gamaleya Institute is taking place in 29 clinics across Moscow and will involve 40,000 volunteers in total, with a quarter receiving a placebo shot. The chances of contracting COVID-19 were 92% lower among people vaccinated with Sputnik V than those who received the placebo, the RDIF said. That's well above the 50% effectiveness threshold for COVID-19 vaccines set by the U.S. Food and Drug Administration. "I can see no a priori reason to disbelieve these results, but it's so very hard to comment, because there is so little data there," said Danny Altmann, a professor of Immunology at Imperial College London. He said that while the Russian release was similar in its level of detail to the one from Pfizer and BioNTech, the key difference was that Pfizer's release came against a backdrop of a wealth of published data on how the trial was designed, its protocol, and what its endpoints were. The results of the early-stage trials were peer reviewed and published in September in The Lancet medical journal. SPUTNIK V The Russian drug is named Sputnik V after the Soviet-era satellite that triggered the space race, a nod to the project's geopolitical importance for Russian President Vladimir Putin. The vaccine is designed to trigger a response from two shots administered 21 days apart, each based on different viral vectors that normally cause the common cold: human adenoviruses Ad5 and Ad26. The Pfizer and BioNTech vaccine uses messenger RNA (mRNA) technology and is designed to trigger an immune response without using pathogens, such as actual virus particles. Russia is also testing a different vaccine, produced by the Vector Institute in Siberia, and is on the cusp of registering a third, Putin said on Tuesday, adding that all of the country's vaccines were effective. RDIF said as of Nov. 11 no serious side effects had been reported during the Sputnik V Phase III trial. Some volunteers had short-term minor adverse events such as pain at the injection site, flu-like syndrome including fever, weakness, fatigue, and headache, it said. MASS VACCINATIONS Successful vaccines are seen as a crucial to restoring daily life around the world by helping end the health crisis that shuttered businesses and put millions out of work. Russia registered the vaccine for domestic use in August, and has also inoculated 10,000 people considered at high risk of COVID-19 outside of the trial Putin has said that Russia expects to start mass vaccinations by the end of the year. "The publication of the interim results of the post-registration clinical trials that convincingly demonstrate Sputnik V vaccine’s efficacy gives way to mass vaccination in Russia against COVID-19 in the coming weeks," Alexander Gintsburg, director of the Gamaleya Institute, said. Moscow is rolling out a large network of vaccination rooms and residents who want the shot may be able to get it as early as next month if large volumes of doses are supplied by then, Deputy Mayor Anastasia Rakova said on Oct. 30. However, production challenges remain. Earlier estimates that Russia could produce 30 million doses of the vaccine this year have since been scaled down. Moscow aims to produce 800,000 doses this month, industry minister Denis Manturov has said, followed by 1.5 million in December. But significantly higher volumes of output per month are expected from early 2021. Manturov cited issues with scaling up production from small to large-volume bioreactors, while Putin last month cited issues with the availability of equipment. In late October, the vaccination of new volunteers was temporarily paused due to high demand and a shortage of doses. Officials have said that domestic production of the vaccine will be used first to meet Russia's needs. RDIF, however, has also struck several international supply deals, amounting to 270 million doses in total. It is expected that these will in large part be produced in other countries and RDIF has previously announced a deal to manufacture 300 million doses in India and an undisclosed amount of doses in Brazil, China and South Korea. Trials have also begun in Belarus, and are on track to begin soon in the United Arab Emirates, Venezuela and India. Russia reported 19,851 new coronavirus infections in the past 24 hours and a record high of 432 deaths. At 1,836,960, its overall case tally is the fifth largest in the world, behind the United States, India, Brazil and France. -- © Copyright Reuters 2020-11-11 - Whatever you're going through, the Samaritans are here for you - Follow Thaivisa on LINE for breaking COVID-19 updates 2 1 Link to comment Share on other sites More sharing options...
KannikaP Posted November 11, 2020 Share Posted November 11, 2020 And it's going to go around the World! LOL Link to comment Share on other sites More sharing options...
Dcheech Posted November 11, 2020 Share Posted November 11, 2020 (edited) 92 per cent! Beating Pfizer's 90 per cent effective vaccine. After the problems the Russians had with their first attempt, who would have guessed the second would come in with flying colors and beat Pfizer's/BionTech's vaccine just days later. Quote "I can see no a priori reason to disbelieve these results, but it's so very hard to comment, because there is so little data there," said Danny Altmann, a professor of Immunology at Imperial College London. No reason to worry. Edited November 11, 2020 by Dcheech 1 Link to comment Share on other sites More sharing options...
Popular Post sammieuk1 Posted November 11, 2020 Popular Post Share Posted November 11, 2020 No that's Novichock at 92% ???? 1 1 4 Link to comment Share on other sites More sharing options...
Popular Post Justgrazing Posted November 11, 2020 Popular Post Share Posted November 11, 2020 23 minutes ago, snoop1130 said: Russia's announcement follows swiftly on from results posted on Monday by Pfizer and BioNTech, which said their shot was also more than 90% effective What a coincidence .. 24 minutes ago, snoop1130 said: Experts said knowledge about the trial's design and protocol was sparse, making it difficult to interpret the figures released on Wednesday What a surprise .. 4 1 Link to comment Share on other sites More sharing options...
Popular Post oompie69 Posted November 11, 2020 Popular Post Share Posted November 11, 2020 Do I hear 95 from North Korea?????????? 2 9 Link to comment Share on other sites More sharing options...
Popular Post scubascuba3 Posted November 11, 2020 Popular Post Share Posted November 11, 2020 A lot of pressure on these companies to manipulate the data and keep beating each other, soon 110% 4 Link to comment Share on other sites More sharing options...
bartender100 Posted November 11, 2020 Share Posted November 11, 2020 One thing that will come out of this, medical science on viruses will have leaped significantly for the benefit of mankind, just like technology does in wartime 2 Link to comment Share on other sites More sharing options...
ukrules Posted November 11, 2020 Share Posted November 11, 2020 The only way is up, there's 2 major vaccines from the UK, at least one of which doesn't require -80 C storage and transportation coming up very soon. It will be interesting to hear the efficacy of these two very new vaccines. 1 Link to comment Share on other sites More sharing options...
mlmcleod Posted November 12, 2020 Share Posted November 12, 2020 The real question about vaccines is how long will they be effective? No vaccine will be successful it loses effectiveness in 4 months as has been reported. Link to comment Share on other sites More sharing options...
Rookiescot Posted November 12, 2020 Share Posted November 12, 2020 It could be but it would require a level of cooperation between nations on a scale never seen before. And of course there would be some nations which would flat out refuse to take part. Could you imagine a huge medical team from countries like the USA and Europe being allowed into North Korea to treat people there? Link to comment Share on other sites More sharing options...
Proboscis Posted November 12, 2020 Share Posted November 12, 2020 2 hours ago, mlmcleod said: The real question about vaccines is how long will they be effective? No vaccine will be successful it loses effectiveness in 4 months as has been reported. Actually vaccine effectiveness tails off rather than suddenly stops becomming ineffective. But lets say it is 90% effective for 4 months. That is equivalent to a 4 month shutdown. The virus might never survive it if the whole population took the vaccine. Of course, life is never like that - it would probably take at least 4 months to roll out the vaccine in a large country. And you would have lots of dumb people who would take the first shot but not the second. But just a 90% effectiveness rate tailing off after 4 months would allow the economy to open up again, to fly and use hotels probably with some use of masks in crowded places etc. I would take that. For the really vulnerable, you could give them their shots every six months. Link to comment Share on other sites More sharing options...
Andy from Kent Posted November 12, 2020 Share Posted November 12, 2020 17 hours ago, Dcheech said: 92 per cent! Beating Pfizer's 90 per cent effective vaccine. After the problems the Russians had with their first attempt, who would have guessed the second would come in with flying colors and beat Pfizer's/BionTech's vaccine just days later. No reason to worry. I think I would trust the Germans more than I would the Russians in their claims. 1 1 Link to comment Share on other sites More sharing options...
tomauasia Posted November 12, 2020 Share Posted November 12, 2020 No way l go near this Russian rubbish 1 Link to comment Share on other sites More sharing options...
Buba Ho Tep Posted November 12, 2020 Share Posted November 12, 2020 I do hope it will be available in Thailand! Link to comment Share on other sites More sharing options...
Dmitry2222 Posted November 12, 2020 Share Posted November 12, 2020 10 hours ago, tomauasia said: No way l go near this Russian rubbish Dont worry, all dosses already sold. You have to wait for a democratic vaccine ????. Link to comment Share on other sites More sharing options...
RichCor Posted November 12, 2020 Share Posted November 12, 2020 Noticed this thread, then today say this news story: Three medical workers who took Russian vaccine reportedly infected with COVID-19 New York Post | By Yaron Steinbuch | November 11, 2020 | 7:35am Three vaccinated Russian doctors catch COVID-19 as country claims its drug beats Pfizer’s BGR | by Chris Smith | November 12th, 2020 at 2:43 PM Link to comment Share on other sites More sharing options...
tomauasia Posted November 13, 2020 Share Posted November 13, 2020 13 hours ago, Dmitry2222 said: Dont worry, all dosses already sold. You have to wait for a democratic vaccine ????. With pleasure. Putin full of <deleted> Link to comment Share on other sites More sharing options...
Dmitry2222 Posted November 13, 2020 Share Posted November 13, 2020 1 hour ago, tomauasia said: With pleasure. Putin full of <deleted> "If you hate it means you lost". Confucius. Perhaps, you do not winner in you life ????. Link to comment Share on other sites More sharing options...
Dmitry2222 Posted November 13, 2020 Share Posted November 13, 2020 10 hours ago, RichCor said: Three vaccinated Russian doctors catch COVID-19 as country claims its drug beats Pfizer’s ok, let me tell you a secret, a vaccine is not a guarantee that you won't get sick. it may happen, but in a mild form. Link to comment Share on other sites More sharing options...
onebir Posted November 13, 2020 Share Posted November 13, 2020 On 11/12/2020 at 4:07 AM, mlmcleod said: No vaccine will be successful it loses effectiveness in 4 months as has been reported. An oral vaccine that doesn't require refrigeration could still be very useful though. Link to comment Share on other sites More sharing options...
RichCor Posted November 13, 2020 Share Posted November 13, 2020 14 minutes ago, Dmitry2222 said: 10 hours ago, RichCor said: Three vaccinated Russian doctors catch COVID-19 as country claims its drug beats Pfizer’s ok, let me tell you a secret, a vaccine is not a guarantee that you won't get sick. it may happen, but in a mild form. You shouldn't be telling secrets Dmitry. The news stories are bunk. Just because 3 vaccinated people later becoming Covid-19 positive means nothing. It's statistically insignificant, and there are too many reasons to explain why 3 vaccinations may have failed. When the self-serving writer of these news stories can show 300 or 3000 similar instances then I might be interested in actually reading the article. What I want to see are after-action studies, what is the overall efficacy, duration of protection, side-effects, can this vaccine protect the inoculated against American stupid (that will be an ever ongoing infection vector threat). Link to comment Share on other sites More sharing options...
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