WHO pauses trial of hydroxychloroquine in COVID-19 patients due to safety concerns

[Bluespunk]

5 minutes ago, riclag said:

Go talk to the FDA,will ya,it's their words

I don’t need to, their words do not say it is proven to act as a prophylaxis against covid-19. 

[candide]

1 hour ago, Crazy Alex said:

Yer killin' me, smalls! ????

 

What, like there are no people in other countries that hate Trump? You guys usually wear worldwide hatred of Trump as a medal. Why be so coy now? As for a conspiracy, nah. People are just doing what they do. There is no Facebook or other group of different people in different countries coordinating or planning studies to GET TRUMP.

 

It just happens with these people naturally.  ????

 

Of course, we have to keep everything in context. The hatred and disapproval of HCQ after Trump talking nice about it was swift, voluminous and severe.

Scientists worldwide faking scientific studies because they don't like Trump. ????

You know, I heard tinfoil also work well when you stick it on walls

Edited May 26, 2020 by candide

[OZinPattaya]

18 hours ago, simple1 said:

WHO did not refuse to investigate hydroxycholoroquine, the WHO has temporarily suspended further research whilst the safety data is reviewed.

 

China has granted a doubling of US withdrawn funding over the next two years for WHO totalling two billion dollars. Accordingly your other comments makes no sense whatsoever. Out of curiosity how much of the WHO budget is spent on luxuries. 

Hmmm, I wonder why that is, that China would re-double its WHO contribution. Could it have something to do with deflecting its global responsibility? Of course not.

[Crazy Alex]

2 hours ago, Bluespunk said:

HCQ is medically proven but not for what trump is using it. 

There's certainly a scientific basis to believe it is effective for prohylaxis. Of course, Trump has access to the very best doctors and I'm sure they know what they're doing.

 

"In-vitro studies have shown that chloroquine is effective against several viruses, including severe acute respiratory syndrome coronavirus (SARS-CoV). Multiple mechanisms of action have been identified for chloroquine that disrupt the early stage of coronavirus replication. Moreover, chloroquine affects immune system activity by mediating an anti-inflammatory response, which might reduce damage due to the exaggerated inflammatory response.At the time of the SARS epidemic, chloroquine was suggested as a drug that could be used to treat this infection."

 

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30296-6/fulltext

 

Edited May 26, 2020 by Crazy Alex

[Crazy Alex]

1 hour ago, candide said:

Scientists worldwide faking scientific studies because they don't like Trump. ????

You know, I heard tinfoil also work well when you stick it on walls

Who said anything about fake studies??????

 

OK, calm down and take a deep breath. Baby steps. Do you think scientists can be biased and be involved in studies in which they have a preferred outcome?

 

Edited May 26, 2020 by Crazy Alex

[candide]

14 minutes ago, Crazy Alex said:

Who said anything about fake studies??????

 

OK, calm down and take a deep breath. Baby steps. Do you think scientists can be biased and be involved in studies in which they have a preferred outcome?

 

So what was exactly did you mean when you wrote: "Yep, look at all those studies, likely most determined to get Trump at all costs."

Edited May 26, 2020 by candide

[Bluespunk]

15 minutes ago, Crazy Alex said:

There's certainly a scientific basis to believe it is effective for prohylaxis. Of course, Trump has access to the very best doctors and I'm sure they know what they're doing.

 

"In-vitro studies have shown that chloroquine is effective against several viruses, including severe acute respiratory syndrome coronavirus (SARS-CoV). Multiple mechanisms of action have been identified for chloroquine that disrupt the early stage of coronavirus replication. Moreover, chloroquine affects immune system activity by mediating an anti-inflammatory response, which might reduce damage due to the exaggerated inflammatory response.At the time of the SARS epidemic, chloroquine was suggested as a drug that could be used to treat this infection."

 

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30296-6/fulltext

 

Clinical trial proof, not “a basis to believe” is the only justification for recommending such a dangerous course of action such as taking hcq as a prophylaxis for covid-19. 
 

Such proof does not yet exist. 
 

Proof of the dangers of hcq use does exist. 
 

iIt should only be used as a last resort in situations medical proof dictates it should. 

Edited May 26, 2020 by Bluespunk

[Crazy Alex]

1 minute ago, candide said:

So what was exactly your intent when you wrote: "Yep, look at all those studies, likely most determined to get Trump at all costs."

That was me stirring things up. ????

[Crazy Alex]

1 minute ago, Bluespunk said:

Clinical trial proof, not “a basis to believe” is the only justification for recommending such a dangerous course of action such as taking hcq as a prophylaxis for covid-19. 
 

Such proof does not yet exist. 

Thanks for that. I'll assume Trump's doctors know better than you if you don't have reason for me to believe otherwise. We're supposed to listen to the professionals, correct?

[candide]

2 minutes ago, Crazy Alex said:

Thanks for that. I'll assume Trump's doctors know better than you if you don't have reason for me to believe otherwise. We're supposed to listen to the professionals, correct?

What did his doctor exactly state?

[Bluespunk]

5 minutes ago, Crazy Alex said:

Thanks for that. I'll assume Trump's doctors know better than you if you don't have reason for me to believe otherwise. We're supposed to listen to the professionals, correct?

Regardless of what you claim, there is no clinical evidence it acts as a prophylaxis. To recommend such a dangerous course of action without proof is highly irresponsible of trump. 

Edited May 26, 2020 by Bluespunk

[Crazy Alex]

1 minute ago, candide said:

What did his doctor exactly state?

How should I know? Why would I care? A doctor gave him a prescription. Why would I need to have a detailed statement?????

[simple1]

4 hours ago, OZinPattaya said:

Hmmm, I wonder why that is, that China would re-double its WHO contribution. Could it have something to do with deflecting its global responsibility? Of course not.

One could equally claim China, not for the first time, out maneuvered trump in the influencing / diplomacy game. 

[RJRS1301]

11 hours ago, steve73 said:

HCQ has been used as a prophylactic for Malaria for many decades, and a heart arrhythmia was never mentioned as a contra-indication,

Perhaps you have never read the list of contraindications prior to 2020, but atrial fibrillation has been mentioned for decades.

 

Jul 19, 2018 - Atrial fibrillation is the most common arrhythmia in clinic. It can lead to heart failure or stroke, and has a high disability rate and mortality rate. ... In recent decades, no effective new antiarrhythmic drugs have been introduced, but ... At present, hydroxychloroquine is mainly used in the treatment of rheumatic ...

 

Effect of Hydroxychloroquine on Atrial Fibrillation Recurrence ...

clinicaltrials.gov › show › NCT03592823

 

1.  

 

[checkered flag]

The responses here are primarily based on if you support Donald Trump or not. HCQ is worth looking at and may provide good or not good outcomes. This should be based on science not politics, 

The scientific method is based on trial and error. HQC has been used successfully for 65 years so it's worth a shot. If it doesn't prove useful it should be canned. By mentioning it Trump forced the FDA to act fast and not proceed with the usual long laborious trials. Long trials benefits big pharma by preventing competition and keep profits high.

 

[metisdead]

A post with a link to an unapproved YouTube source has been removed:

 

 

18) Social Media content is not to be used as  source material unless it is from a recognized or approved news media source,  the source of any such material (Twitter, Facebook, YouTube  etc.) should always be shown.

[checkered flag]

7 hours ago, Bluespunk said:

Clinical trial proof, not “a basis to believe” is the only justification for recommending such a dangerous course of action such as taking hcq as a prophylaxis for covid-19. 
 

Such proof does not yet exist. 
 

Proof of the dangers of hcq use does exist. 
 

iIt should only be used as a last resort in situations medical proof dictates it should. 

So while sitting on our hands waiting for absolute proof, we do nothing and let people suffer and die. How progressive of you. 

[Phil McCaverty]

9 minutes ago, checkered flag said:

So while sitting on our hands waiting for absolute proof, we do nothing and let people suffer and die. How progressive of you. 

 People are not sitting on their hands, people are looking for real, scientifically proven solutions, like vaccines. Oxford University are pretty close to doing that. Hydroxychloroquine provides no solutions to Covid-19. It kills more than it cures. Its a dead end for researchers.

 

How progressive of you to drink the Trump kool aid and spout rhetorical nonsense. His MO for running a country and ridding America of Covid-19.

 

 

[checkered flag]

2 minutes ago, Phil McCaverty said:

 People are not sitting on their hands, people are looking for real, scientifically proven solutions, like vaccines. Oxford University are pretty close to doing that. Hydroxychloroquine provides no solutions to Covid-19. It kills more than it cures. Its a dead end for researchers.

 

How progressive of you to drink the Trump kool aid and spout rhetorical nonsense. His MO for running a country and ridding America of Covid-19.

 

 

The kool aid quip comes from the actions of Jim Jones who was a progressive if I recall right. Lets look at the Oxford study when complete. Hope it is thorough and clear cut.

BTW are you still looking for free handouts from your days on the streets as a backpacker. 

[Phil McCaverty]

4 minutes ago, checkered flag said:

BTW are you still looking for free handouts from your days on the streets as a backpacker. 

Nice trolling. Your specialised subject. I was a glampacker. No hostels or guesthouses for me. No need for handouts when you carry American Express Platinum.

[Bluespunk]

2 hours ago, checkered flag said:

So while sitting on our hands waiting for absolute proof, we do nothing and let people suffer and die. How progressive of you. 

I’m saying that it is better not to take a drug, with dangerous side effects, as a prophylaxis when it has not been proven it works as one. 

Edited May 27, 2020 by Bluespunk

[checkered flag]

6 minutes ago, Bluespunk said:

Not what I said.
 

I’m saying that it is better not to take a drug, with dangerous side effects, as a prophylaxis when it has not been proven it works as one. 

The dangerous side effects is not that it's been used for other things for 65 years. It surely is that it was mentioned by Donald Trump. Aspirin and tylenol can be toxic as well.  

[johnnybangkok]

On 5/26/2020 at 6:38 AM, TopDeadSenter said:

Very childish. So the WHO got their butt smacked by Trump. Now they refuse to investigate one of the most promising drugs to treat/prevent the disease their coziness with Beijing allowed to spread. Well with their funding axed by the largest (by far) contributor, they will have to prioritize spending. I would have recommended they cutting out spending on luxuries, but then I'm not the one having a tantrum.

As usual your over simplification of everything concerning Trump blinds you to facts.

 

The WHO are one of MANY who have dismissed this drug, with Americas own FDA being the most prominent. 

https://www.fda.gov/drugs/drug-safety-and-availability/fda-cautions-against-use-hydroxychloroquine-or-chloroquine-covid-19-outside-hospital-setting-or

 

Medical tests confirm 'We were unable to confirm a benefit of hydroxychloroquine or chloroquine, when used alone or with a macrolide, on in-hospital outcomes for COVID-19'   https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31180-6/fulltext 

 

A study just published in a French medical journal provides new evidence that hydroxychloroquine does not appear to help the immune system clear the coronavirus from the body. https://www.thailandmedical.news/news/breaking-covid-19-drug-research-study-shows-that-hydroxychloroquine-and-azithromycin-has-no-effect-on-covid-19-patients,-no-better-than-a-dangerous-p

 

Why does everything have to be some big conspiracy for you guys? It's really quite simple; Trump has been touting a drug with no scientific evidence to back up his argument. This is negligent at best, downright dangerous at worse.

[Bluespunk]

7 minutes ago, checkered flag said:

The dangerous side effects is not that it's been used for other things for 65 years. It surely is that it was mentioned by Donald Trump. Aspirin and tylenol can be toxic as well.  

And no one is recommending them as a prophylaxis for covid-19 either. 
 

The dangers of using hcq are based on clinical trials, nothing to do with trump. 

Edited May 27, 2020 by Bluespunk

[Phil McCaverty]

10 minutes ago, checkered flag said:

Aspirin and tylenol can be toxic as well. 

And me! Don't forget me. 555

[tlandtday]

On 5/26/2020 at 7:11 AM, RJRS1301 said:

Did you read why they have "suspended" , different from refusing to investigate as you state.

Always a good idea to investigate RISKS to human life and well-being. IMHO

Not everything is a conspiracy theory against your POTUS

 

"The executive group has implemented a temporary pause of the hydroxychloroquine arm within the Solidarity trial while the safety data is reviewed by the data safety monitoring board," Tedros told an online briefing."

 

(Reporting by Michael Shields; Writing by Peter Graff; Editing by John Stonestreet)

 

-- © Copyright Reuters 2020-05-26

 

 

Get real this is a drug that is used by millions each year for malaria with little or no negatives.

[RJRS1301]

50 minutes ago, tlandtday said:

Get real this is a drug that is used by millions each year for malaria with little or no negatives.

You are correct used for Lupus and Malaria, not COVID19, a respiratory illness.

Not recommended for that one>> get real

Atrial Fibrillation one of the known side effects when used for recommended use, as well as when used for non licenced reasons (like Covid19) 

 

Edited May 27, 2020 by RJRS1301

[ChouDoufu]

you guys are so behind the flattened curve!

bleach and uv bulbs are so last week, and hydrocloroxywhatsis is sooo yesterday.

today the magic pill is.....insulin!

 

"I don't use insulin," Trump said. "Should I be? Huh? I never thought about it. But I know a lot of people are very badly affected, right? Unbelievable."

 

https://www.msn.com/en-us/news/other/trump-asks-whether-he-should-be-taking-insulin-despite-not-being-diabetic/ar-BB14DCcZ?li=BBnbcA1

[checkered flag]

22 hours ago, ChouDoufu said:

you guys are so behind the flattened curve!

bleach and uv bulbs are so last week, and hydrocloroxywhatsis is sooo yesterday.

today the magic pill is.....insulin!

 

"I don't use insulin," Trump said. "Should I be? Huh? I never thought about it. But I know a lot of people are very badly affected, right? Unbelievable."

 

https://www.msn.com/en-us/news/other/trump-asks-whether-he-should-be-taking-insulin-despite-not-being-diabetic/ar-BB14DCcZ?li=BBnbcA1

Did you actually read the article, it in plain english. It was about the affordability of the hormone and Trumps efforts to make sure those in need get it. Get a life.

[Redline]

On 5/26/2020 at 6:38 AM, TopDeadSenter said:

Very childish. So the WHO got their butt smacked by Trump. Now they refuse to investigate one of the most promising drugs to treat/prevent the disease their coziness with Beijing allowed to spread. Well with their funding axed by the largest (by far) contributor, they will have to prioritize spending. I would have recommended they cutting out spending on luxuries, but then I'm not the one having a tantrum.

I would hate to see your reading comprehension scores ????