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Lancet: "Fully vaccinated individuals with breakthrough infections have peak viral load similar to unvaccinated cases"


ArcticFox

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This is rather disconcerting.  New Lancet article regarding transmission of SARS-Cov-2 in vaccinated and unvaccinated.

Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study
Anika Singanayagam, PhD et.al., Oct 29, 2021, The Lancet, Infectious Diseases
 

"Interpretation.  Vaccination reduces the risk of delta variant infection and accelerates viral clearance. Nonetheless, fully vaccinated individuals with breakthrough infections have peak viral load similar to unvaccinated cases and can efficiently transmit infection in household settings, including to fully vaccinated contacts. Host–virus interactions early in infection may shape the entire viral trajectory."

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00648-4/fulltext

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Vaccination reduces the risk of delta variant infection and accelerates viral clearance.

 

Nonetheless, fully vaccinated individuals with breakthrough infections have peak viral load similar to unvaccinated cases and can efficiently transmit infection in household settings, including to fully vaccinated contacts. 

 

There are a number of conditional probabilities here.

 

1. Infected given vaccinated.

2. Infected given vaccinated and still not clear of viral load. 

3. Break through infection given vaccinated.

 

and can efficiently transmit infection in household settings, including to fully vaccinated contacts. 

 

Yes but 

 

Vaccination reduces the risk of delta variant infection and accelerates viral clearance.

------------

 

Vaccination reduces the probability of infection, transmission, serious illness, hospitalisation and death. 

 

Stick with the jab.

 

 

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2 hours ago, ArcticFox said:

This is rather disconcerting.

I guess we're rather fortunate that the better vaccines with proven track records of success (Moderna, Pfizer, AZ) do a very good job at preventing "breakthrough infections" -- even though on average a very small share of breakthroughs do occur. Nothing works 100% of the time.

 

"How common are breakthrough cases of COVID?

A study in Washington state gathered data from over 4 million fully vaccinated people. The data showed a rate of about 1 in 5,000 experienced a breakthrough infection between January 17 and August 21, 2021. More recently, some populations have shown breakthrough infection rates of approximately 1 in 100 fully vaccinated people."

 

AND

 

"Is coronavirus after vaccination dangerous?

Breakthrough coronavirus infections can cause mild or moderate illness, but the chances of serious COVID-19 are very low, especially for people who are not living with a chronic health condition.

 

The COVID-19 vaccines are very effective in keeping you from having to go to the hospital, being put on a ventilator or dying due to severe coronavirus disease, including COVID caused by the delta coronavirus variant."

 

https://www.hopkinsmedicine.org/health/conditions-and-diseases/coronavirus/breakthrough-infections-coronavirus-after-vaccination

 

Edited by TallGuyJohninBKK
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