Mycoplasma Genitalium (Mgen) where to find alternative antibiotics?

[MajesticZebra]

I am looking for minocycline, pristinamycin, josamycin, or lefamulin to treat my MGEN. 
 

i have already tried doxycycline and azythromycin. I will not try Moxifloxacin because of the black box label and potential for permanent disabling side effects. 
 

Could anyone please help me in finding these alternative antibiotics in Thailand or if i can get them shipped? 
 

i have tried multiple hospitals and many many pharmacies. 

[Jai Dee]

Topic moved to Health Forum.

 

/Moved.

[xylophone]

Not sure that I have ever seen minocycline here although minocin seemed to be available a while ago, but was mainly used for acne treatment.

 

I found this when looking on the Internet, but you appear to have tried some of these, so this might not be of interest to you: –

 

What is the fastest way to cure mycoplasma?
Antibiotics such as erythromycin, clarithromycin or azithromycin are effective treatment. However, because mycoplasma infection usually resolves on its own, antibiotic treatment of mild symptoms is not always necessary.

 

If all else fails you could order them online from an Indian pharmacy, which I have done just recently and here is the link, they do sell minocycline (as Cynomycin), and you won't need a prescription (or at least I never have when ordering from them) but you will need to research what dosage you will need to treat your condition.

 

https://www.shreemedical.com/search.php
 

[Sheryl]

Of the antibiotics mentioned only one, minocycline, has a brand registered in Thailand, brand name Minocin but very hard to find and the Mims listing does nto even tell the manufacturer--- which often means it is off market.

 

In addition, if doxycycline did not work, minocycline is not likely to either.

 

I suggest you go to the Thai Red Cross anonymous clinic, they are the most up to date in Thailand on treatment of STIs and would know (and have) whatever is currently found most effective here.  And they may have drugs not otherwise readily obtained.

[scubascuba3]

Did you try Doxycycline for 7 days followed by 3 days of 500mg  azithromycin? worked for me.

 

If in Pattaya or Bangkok a small busy clinic may know the best way to treat as they see so many people. I have one near me on Pattaya Tai

[voyagerUSA]

For minocycline it is almost impossible to get here in Thailand but may be able to order it from India for example

 

For the other more exotic antibiotics you may need to see an infectious disease specialist at one of the top private hospitals, see if they can import it for you somehow. Alternatively you may need to travel outside thailand for treatment.

 

Like this guy might be able to help you - but it will be expensive

 

https://www.medparkhospital.com/en/doctor/assist-prof-dr-thanomsak-anekthananon

[voyagerUSA]

Fluoroquinolone antibiotics do have that black box warning but the actual rate of serious side effects I think is very low. Still doxycycline or minocycline are safer, if they work.

[mayawame]

Melbourne Sexual Health Centre mentions treatment with a Sitafloxacin combo for resistant MG.

 

https://www.mshc.org.au/health-professionals/treatment-guidelines/mycoplasma-genitalium-treatment-guidelines

[Sheryl]

3 hours ago, mayawame said:

Melbourne Sexual Health Centre mentions treatment with a Sitafloxacin combo for resistant MG.

 

https://www.mshc.org.au/health-professionals/treatment-guidelines/mycoplasma-genitalium-treatment-guidelines

Not avalaible in Thailand and also a quinolone which OP is afraid to take.

 

Pripr poster's comment about seriosu side effects not being that common are, however, correct. In fact the tendon injury OP is concerned about occurs in less than 0.5% of people...and tmainly occur with prolonged use; MGEN needs only 7 day course.  If I were OP I would go ahead and take Moxifloxacin provided  the diagnosis has been confirmed i.e. PCR test and is not a self diagnosis.

[RB7829]

Do you have Candidiasis ? ( trush )

[Lorry]

4 hours ago, Sheryl said:

Not avalaible in Thailand and also a quinolone which OP is afraid to take.

Sitafloxacin is easily available in Thailand

Brand name Gracevit, 1200B.

But, yes, it is a quinolone.

[Sheryl]

13 hours ago, Lorry said:

Sitafloxacin is easily available in Thailand

Brand name Gracevit, 1200B.

But, yes, it is a quinolone.

You are right. I must have mispelled it in the search.

[xylophone]

On 5/21/2023 at 4:18 PM, scubascuba3 said:

Did you try Doxycycline for 7 days followed by 3 days of 500mg  azithromycin? worked for me.

This is a good suggestion because the research I have done, albeit not too much, does suggest that a doubling up of antibiotics can get rid of MG.

 

And although I'm not a fan of fluoroquinolones, having had a bad case of Achilles tendinitis after taking it for two weeks, as Sheryl has said, the percentage of people who it affects is very small.....

 

What percentage of people have a bad reaction to Cipro?

These serious side effects can happen in less than 1 in 100 people. Stop taking ciprofloxacin and tell your doctor or contact 111 straight away if you have: muscle weakness, pain or swelling in your joints or tendons.

Side effects of ciprofloxacin - NHS

www.nhs.uk

https://www.nhs.uk › medicines › side-effects-of-ciproflo.

[scubascuba3]

58 minutes ago, xylophone said:

This is a good suggestion because the research I have done, albeit not too much, does suggest that a doubling up of antibiotics can get rid of MG.

 

And although I'm not a fan of fluoroquinolones, having had a bad case of Achilles tendinitis after taking it for two weeks, as Sheryl has said, the percentage of people who it affects is very small.....

 

What percentage of people have a bad reaction to Cipro?

These serious side effects can happen in less than 1 in 100 people. Stop taking ciprofloxacin and tell your doctor or contact 111 straight away if you have: muscle weakness, pain or swelling in your joints or tendons.

Side effects of ciprofloxacin - NHS

www.nhs.uk

https://www.nhs.uk › medicines › side-effects-of-ciproflo.

Doxycycline weakens it, symptoms stop quickly but you need another antibiotic to finish it off. Can try Azithromycin first, if that doesn't work then next in line

[MajesticZebra]

On 5/21/2023 at 2:47 PM, xylophone said:

Not sure that I have ever seen minocycline here although minocin seemed to be available a while ago, but was mainly used for acne treatment.

 

I found this when looking on the Internet, but you appear to have tried some of these, so this might not be of interest to you: –

 

What is the fastest way to cure mycoplasma?
Antibiotics such as erythromycin, clarithromycin or azithromycin are effective treatment. However, because mycoplasma infection usually resolves on its own, antibiotic treatment of mild symptoms is not always necessary.

 

If all else fails you could order them online from an Indian pharmacy, which I have done just recently and here is the link, they do sell minocycline (as Cynomycin), and you won't need a prescription (or at least I never have when ordering from them) but you will need to research what dosage you will need to treat your condition.

 

https://www.shreemedical.com/search.php
 

Hi man, i tried to look at this website but it doesn’t offer details of the meds. I click quantity does that mean per box or per pill? It doesn’t tell you how many are in the box, so it might be per pill?

[MajesticZebra]

On 5/25/2023 at 12:24 AM, Lorry said:

Sitafloxacin is easily available in Thailand

Brand name Gracevit, 1200B.

But, yes, it is a quinolone.

Are these pills? What does it mean preparation? Are they at most pharmacies?

[Sheryl]

1 hour ago, MajesticZebra said:

Are these pills? What does it mean preparation? Are they at most pharmacies?

They are pills.

 

Not at most pharmacies. Will be difficult to find. 

 

This is a quinolone just like Moxifloxacin. Same black box warning.  Moxifloxacin  will be easier to find.

 

Please note as others said that should not take this alone. Need a course of doxycycline immediately before it even though you have taken doxy before.  If you have not had a PCR to confirm diagnosis it is possible this is not MGen. 

 

Again I urge you go to the TRC Anonymous Clinic. They are the best informed about current local patterns of drug resistance . 

[xylophone]

1 hour ago, MajesticZebra said:

Hi man, i tried to look at this website but it doesn’t offer details of the meds. I click quantity does that mean per box or per pill? It doesn’t tell you how many are in the box, so it might be per pill?

On the website at the top it has links you can click on to get more info/contact them......I have found them very helpful, so ask for more details there.

[xylophone]

2 hours ago, Sheryl said:

They are pills.

 

Not at most pharmacies. Will be difficult to find. 

 

This is a quinolone just like Moxifloxacin. Same black box warning.  Moxifloxacin  will be easier to find.

 

Please note as others said that should not take this alone. Need a course of doxycycline immediately before it even though you have taken doxy before.  If you have not had a PCR to confirm diagnosis it is possible this is not MGen. 

 

Again I urge you go to the TRC Anonymous Clinic. They are the best informed about current local patterns of drug resistance . 

@MajesticZebra I think Sheryls answer is the one you should follow.

[MajesticZebra]

4 hours ago, Sheryl said:

They are pills.

 

Not at most pharmacies. Will be difficult to find. 

 

This is a quinolone just like Moxifloxacin. Same black box warning.  Moxifloxacin  will be easier to find.

 

Please note as others said that should not take this alone. Need a course of doxycycline immediately before it even though you have taken doxy before.  If you have not had a PCR to confirm diagnosis it is possible this is not MGen. 

 

Again I urge you go to the TRC Anonymous Clinic. They are the best informed about current local patterns of drug resistance . 

I have already a confirmed Mgen diagnosis. I have the PCR test paper to prove it. Do you know where I can get Sitafloxacin? I have read Sitafloxacin is easier on the body than Moxifloxacin and doesn’t have as much resistance strains that it will not work on. 

[Sheryl]

38 minutes ago, MajesticZebra said:

I have already a confirmed Mgen diagnosis. I have the PCR test paper to prove it. Do you know where I can get Sitafloxacin? I have read Sitafloxacin is easier on the body than Moxifloxacin and doesn’t have as much resistance strains that it will not work on. 

 

No, I don't know where. It will not be easy to find: there is only one brand here, an expensive import, and it is not widely used. Your best bet is either a large pharmacy near a major hospital (could for example try those near Victory Monument opposite Ratchawithi hospital)  or as previously suggested several times, the TRC Clinic. If there are strains of MGEN in Thailand that are sensitive to it but not to Moxifloxacin, they will probably carry it.

 

Note that antibotic sensitivities do vary by location, what you read on the web may not necessarily reflect the situuation in Thailand.

 

Nothing I have read suggests that Sitafloxacin is in any way "easier on the body'. It carries the same side effect profile as other quinolones (actually higher for some minor things like photophobia).

 

 

[scubascuba3]

1 hour ago, MajesticZebra said:

I have already a confirmed Mgen diagnosis. I have the PCR test paper to prove it. Do you know where I can get Sitafloxacin? I have read Sitafloxacin is easier on the body than Moxifloxacin and doesn’t have as much resistance strains that it will not work on. 

Go to the thai red cross, which has been suggested several times already, cheap also

 

The Thai Red Cross AIDS Research Centre

02 251 6711

https://maps.app.goo.gl/6s5CRHptGwdWecip9

 

 

[Lorry]

1 hour ago, MajesticZebra said:

I have already a confirmed Mgen diagnosis. I have the PCR test paper to prove it. Do you know where I can get Sitafloxacin? I have read Sitafloxacin is easier on the body than Moxifloxacin and doesn’t have as much resistance strains that it will not work on. 

Easier on the body - never heard about this,  i doubt it

Less resistances- yes, sure

Should not be taken as the only therapy for your problem,  as mentioned by others. 

Availability - in Bangkok easy, the usual well stocked pharmacies mentioned in many threads (e.g. Roongroj pharmacy between BigC Onnut or the smaller, not so crowded pharmacy opposite from Roongroj) all have it. Tourist pharmacies on lower Sukhumvit obviously not. Upcountry will be very difficult,  even moxafloxacin is difficult to find upcountry.