Data show Metformin effective against COVID-19

[GroveHillWanderer]

It may be a bit late in the day to be finding this out, but it seems as though there perhaps was (is) a cheap, effective, safe and widely available drug with a significant favorable effect on COVID-19.

 

According to the study below, "Metformin reduced the odds of hospitalizations/death through 28 days by 58%."

 

Favorable Antiviral Effect of Metformin on Covid-19 Viral Load

 

Oh, and just incidentally, the same study also found that, "Neither ivermectin nor fluvoxamine showed effect over placebo."

 

Edited May 3 by GroveHillWanderer

[tomazbodner]

1 hour ago, GroveHillWanderer said:

It may be a bit late in the day to be finding this out, but it seems as though there perhaps was (is) a cheap, effective, safe and widely available drug with a significant favorable effect on COVID-19.

 

According to the study below, "Metformin reduced the odds of hospitalizations/death through 28 days by 58%."

 

Favorable Antiviral Effect of Metformin on Covid-19 Viral Load

 

Oh, and just incidentally, the same study also found that, "Neither ivermectin nor fluvoxamine showed effect over placebo."

 

But what does it do to your sugar levels?

[TallGuyJohninBKK]

Study finds metformin reduces COVID-19 viral load, viral rebound

May 2, 2024

 

A team of University of Minnesota researchers found that metformin, a drug commonly used to treat diabetes, can decrease the amount of COVID-19 virus in the body and lower the chances of the virus coming back strongly after initial treatment. The study was published in Clinical Infectious Diseases.

...

"The results of the study are important because COVID-19 continues to cause illness, both during acute infection and for months after infection," said Carolyn Bramante, MD, principal investigator and an assistant professor at the U of M Medical School. She is also an internist and pediatrician with M Health Fairview.

...

In this phase 3 randomized clinical trial, the researchers tested metformin against a placebo in 1,323 adults infected with COVID-19. The group treated with metformin had a viral load that was about four times lower than the placebo at day 10. The metformin group also had less viral rebound than the placebo group.

 

(more)

 

https://medicalxpress.com/news/2024-05-metformin-covid-viral-rebound.html

 

[TallGuyJohninBKK]

The same research team at the Univ. of Minnesota in the U.S. has done a series of published studies on the effects of metformin against COVID:

 

 Study: Using a diabetes medication after testing positive for SARS-CoV-2 reduces risk of developing long COVID by 40%

 

June 8, 2023

 

Taking a two-week course of metformin, a safe and affordable diabetes medication after testing positive for SARS-CoV-2 leads to 40% fewer long COVID diagnoses over the following 10 months, compared to individuals taking a placebo, finds a new study published in The Lancet Infectious Diseases journal.

 

The long-term symptoms some people experience after SARS-CoV-2 infection, known as long COVID, are an emerging chronic illness potentially affecting millions of people around the world.

...

This is the first phase 3 randomized controlled trial of a treatment for patients in the community that shows a medication can reduce the risk of long COVID when taken after testing positive for SARS-CoV-2.

...

Metformin prevented over 40% of cases of long COVID in the trial with 6.3% (35/564) of participants given metformin reporting a long COVID diagnosis within 10 months of follow up, compared to 10.4% (58/562) of those receiving an identical placebo.

 

(more)

 

https://medicalxpress.com/news/2023-06-diabetes-medication-positive-sars-cov-covid.html

 

Edited May 3 by TallGuyJohninBKK

[GroveHillWanderer]

1 hour ago, tomazbodner said:

But what does it do to your sugar levels?

It reduces them.

 

Effects of metformin on blood glucose levels and bodyweight mediated through intestinal effects

 

"Metformin lowers blood glucose levels by inhibiting gluconeogenesis and increasing insulin sensitivity. Metformin also acts on the intestine, and reduces blood glucose levels and body weight by various mechanisms."

[Robert Paulson]

So should we mandate this too? Maybe deny people ordering a hamburger or boarding a plane if they don’t take it

[tomazbodner]

1 hour ago, Robert Paulson said:

So should we mandate this too? Maybe deny people ordering a hamburger or boarding a plane if they don’t take it

Maybe deny people posting on this forum instead...

[GroveHillWanderer]

2 hours ago, Robert Paulson said:

So should we mandate this too? Maybe deny people ordering a hamburger or boarding a plane if they don’t take it

What on earth are you even on about? This is a therapeutic drug. There are no therapeutic medicines that have ever been mandated for the general public.

Edited May 3 by GroveHillWanderer

[Seppius]

Might live longer as well

 

https://www.health.harvard.edu/blog/is-metformin-a-wonder-drug-202109222605

 

 

"But in recent years, interest has grown regarding its potential to prevent or treat a variety of other conditions, including aging. Yes, aging. If that's true, "wonder drug" might be an understatement."

[Robert Paulson]

5 hours ago, GroveHillWanderer said:

What on earth are you even on about? This is a therapeutic drug. There are no therapeutic medicines that have ever been mandated for the general public.

Yes, crazy talk to mandate treatments, I know. Who would ever propose such an asinine thing

[GroveHillWanderer]

9 hours ago, Robert Paulson said:

Yes, crazy talk to mandate treatments, I know. Who would ever propose such an asinine thing

You obviously don't understand the difference between prophylactic and therapeutic medicines.

[Robert Paulson]

51 minutes ago, GroveHillWanderer said:

You obviously don't understand the difference between prophylactic and therapeutic medicines.

You’re obviously missing the joke. But that’s ok the likes of your ilk have been missing things when it comes to covid for years now