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Thailand helps develop more effective dengue vaccine

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Thailand helps develop more effective dengue vaccine
The Nation

BANGKOK: -- A new anti-dengue vaccine with anticipated improved efficiency is being developed by Thailand jointly with four other countries and will be available here within two years, Department of Disease Control director-general Dr Sophon Mekthon said yesterday.

The new vaccine is expected to protect against four dengue strains found in Thailand. Official registration of this particular vaccine is ongoing with the Food and Drugs Administration.

Dr Usa Thisayakorn, chairwoman of the Paediatric Infectious Disease Society of Thailand, said the unnamed vaccine had proved efficient in protecting against all strains found in the five countries that had jointly developed it - Thailand, Vietnam, Indonesia, the Philippines and Malaysia.

She said its efficacy in preventing dengue was rated at 56 per cent and was rated at 88.5 per cent in decreasing the severity of the disease. Its efficiency has been proved by tests on children aged two to 14 years through three-dose vaccinations. The vaccine has been endorsed by the medical journal The Lancet, she added.

The development of dengue vaccines in Thailand began 20 years ago, and this latest one has been worked on for five years with three hospitals - Photharam, Ban Pong and Kamphaeng Phet - involved.

The new vaccine will now go through follow-up evaluation in a further three phases that will end in 2017 under World Health Organisation regulations.

New dengue strains are capable of infecting adults, unlike earlier strains, which affect mainly children. The new strains could be fatal if contracted by menstruating or pregnant women, Usa warned.

 

Source: http://www.nationmultimedia.com/national/Thailand-helps-develop-more-effective-dengue-vacci-30239512.html

 

[thenation]2014-07-26[/thenation]

Keep up the good work. The exponential increase in dengue affected areas over 30 years is dread inducing.

Good news in a difficult battle.

Maybe a bit of "fake" chest beating, the vaccine was developed by a french company....only being trialed in Thailand. Pity there is still too much BS, from Thai authorities.

Keep up the good work. The exponential increase in dengue affected areas over 30 years is dread inducing.

 

One of the problems is that the minority Dengue Mosquito has two predator mosquitoes. What the Government  should do is to breed the predator mosquitoes rather than kill them which is what thy do when they spray everywhere. There is always a natural way to deal with these things and this particular course of action is being ignored.

Maybe a bit of "fake" chest beating, the vaccine was developed by a french company....only being trialed in Thailand. Pity there is still too much BS, from Thai authorities.

Well the snake farm in Bangkok works closely with the Institut Pasteur in Paris to develop various vaccines so I think they do deserve credit

It seems it is the same story as in 2012, when also 4002 thai children were mentioned, so Sanofi might have just reached another phase in getting FDA approval, maybe CTD 3 or 4.

Interesting read in one Googled article: the backbone of the live vaccine is a Yellowfever virus.
So I was not totally wrong, when getting a Yellowfever vaccination despite not traveling to Latin America since years - because there were unconfirmed studies that a Yellowfever vaccination is reducing the risk to get effected by Dengue and if, is also reducing the effects.

This shows that Thailand is at the forefront of research in areas we never read about. These are the stories that should be heard by the population as well. They are stories to be proud of. To make Thai's feel proud to be Thai.

 

A good friend of mine is a Doctor of Microbiology at Khon Kaen Uni. She studies cow microbes that cause foot rot. Admittedly she did the majority of her study at Melbourne uni, but finished up at KK uni researching this microbe. The break throughs they have made in Isan are being sent back to Melbourne to be further scrutinized. She has travelled back to Melbourne to present her findings and she is a great ambassador for Thailand and Thai's in general.

 

Well done and it is great to hear good news stories that don't involve politics for a change. (Though I do crave them!!)

thailand is a forefront because they allow human guinea pigs for a french company ?

I'll be first in line. I had dengue last year. It wasn't pleasant.

Zoom3, on 26 Jul 2014 - 12:49, said:

 

Rorri, on 26 Jul 2014 - 10:56, said:

Maybe a bit of "fake" chest beating, the vaccine was developed by a french company....only being trialed in Thailand. Pity there is still too much BS, from Thai authorities.

Well the snake farm in Bangkok works closely with the Institut Pasteur in Paris to develop various vaccines so I think they do deserve credit

 

Vaccines or anti-venom for snake bites. In case you missed it, this is about dengue.

This shows that Thailand is at the forefront of research in areas we never read about. These are the stories that should be heard by the population as well. They are stories to be proud of. To make Thai's feel proud to be Thai.

 

A good friend of mine is a Doctor of Microbiology at Khon Kaen Uni. She studies cow microbes that cause foot rot. Admittedly she did the majority of her study at Melbourne uni, but finished up at KK uni researching this microbe. The break throughs they have made in Isan are being sent back to Melbourne to be further scrutinized. She has travelled back to Melbourne to present her findings and she is a great ambassador for Thailand and Thai's in general.

 

Well done and it is great to hear good news stories that don't involve politics for a change. (Though I do crave them!!)

 

 

"This shows that Thailand is at the forefront of research in areas we never read about." - no this shows that YOU never read about this sort of stuff and don't keep up to date. If you had read the background, you'd know that the media is inaccurately reporting the Thai role in this in some papers too.

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