China's Sinovac starts late stage trials for its COVID-19 vaccine

[webfact]

China's Sinovac starts late stage trials for its COVID-19 vaccine

 

FILE PHOTO: Small bottles labeled with "Vaccine" stickers stand near a medical syringe in front of displayed "Coronavirus COVID-19" words in this illustration taken April 10, 2020. REUTERS/Dado Ruvic/Illustration/File Photo

 

LONDON/BEIJING (Reuters) - China's Sinovac Biotech is starting Phase III trials of its potential coronavirus vaccine in Brazil, it said on Monday, becoming one of three companies to move into the late stages in the race to develop an inoculation against the disease.

 

It follows a fast-track approval for the trials by Brazilian regulators last week.

 

Sinovac said the study, which will be done in partnership with Brazilian vaccine producer the Instituto Butantan, would recruit nearly 9,000 healthcare professionals working in COVID-19 specialised facilities and start this month.

 

AstraZeneca's experimental COVID-19 vaccine, developed by researchers at the University of Oxford, and China National Pharmaceutical Group (Sinopharm) are the only other candidates in late-stage Phase III trials.

 

Moderna also plans to start its late-stage trial this month.

 

Sinovac initiated the development of the vaccine candidate in late January and is preparing a coronavirus vaccine plant, which it hopes will be ready this year and capable of making up to 100 million shots a year.

 

Phase I and Phase II trials typically test the safety of a drug before it enters Phase III trials that test its efficacy.

 

The World Health Organization (WHO) says there are 19 vaccine trials in clinical evaluation and hundreds being developed and tested around the world to stop the COVID-19 pandemic, which has killed hundreds of thousands of people and ravaged the global economy.

 

No COVID-19 vaccine has yet been approved for commercial use. A Massachusetts Institute of Technology analysis last year found that about one in three vaccines in the first stage of testing later gains approval.

 

(Reporting by Josephine Mason in London and Roxanne Liu in Beijing; Editing by David Clarke and Stephen Coates)

 

-- © Copyright Reuters 2020-07-07

 

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[Tug]

Hope it’s a winner we are all overdue for some good news

[Eric Loh]

6 minutes ago, Tug said:

Hope it’s a winner we are all overdue for some good news

Certainly overdue for some positive development on the vaccine front and also hope that if successful, it will be a global sharing response to the production and proliferation devoid of geo-politics brinkmanship and self serving politics.  

[grumpy 4680]

5 hours ago, Eric Loh said:

     Certainly overdue for some positive development on the vaccine front and also hope that if successful,

  Quite right, but lets be fair, China had a head start with covid samples, before it was released.

[GreasyFingers]

7 hours ago, Eric Loh said:

Certainly overdue for some positive development on the vaccine front and also hope that if successful, it will be a global sharing response to the production and proliferation devoid of geo-politics brinkmanship and self serving politics.  

I hope you are not holding your breath for that to happen.

[Eric Loh]

32 minutes ago, GreasyFingers said:

I hope you are not holding your breath for that to happen.

When that polarizing world leader leader is voted out in November and leave office in January, there will be better unity in dispensing the vaccine. 

[timendres]

Just now, webfact said:

Sinovac initiated the development of the vaccine candidate in late January and is preparing a coronavirus vaccine plant, which it hopes will be ready this year and capable of making up to 100 million shots a year.

Then comes this problem. 100M / Y into 7B people. That is 70 years.
It will require some serious capacity to deal with the demand.

[Proboscis]

2 hours ago, grumpy 4680 said:

  Quite right, but lets be fair, China had a head start with covid samples, before it was released.

To be fair, it is clear that Covid-19 did not come from a lab.

The reason why they have roped in Brazil is because they need a country with a high number of infectious cases to see if the vaccine works. Clearly China no longer has. In fact, even though UK is not a stunning success, it has managed to get the number of cases down to a level where it is not possible to test out a vaccine and so at least one of their big hopes is also going to Brazil too.

[candide]

What is striking is that market leaders, such as Merck, are quite discreet re. Coronavirus vaccine.

[candide]

27 minutes ago, timendres said:

Then comes this problem. 100M / Y into 7B people. That is 70 years.
It will require some serious capacity to deal with the demand.

Well, it will be only 14 years to serve China! ????

 

Interestingly enough, there are plenty of related issues

https://www.businessinsider.fr/us/coronavirus-vaccine-glass-vial-shortage-could-delay-global-rollout-2020-5

[Tug]

3 hours ago, candide said:

What is striking is that market leaders, such as Merck, are quite discreet re. Coronavirus vaccine.

Well sure they can grift lots of money from desperate people 

[rabas]

12 hours ago, Eric Loh said:

Certainly overdue for some positive development on the vaccine front and also hope that if successful, it will be a global sharing response to the production and proliferation devoid of geo-politics brinkmanship and self serving politics.  

You might want to watch today's presentation by FBI Director Chris Wray on all the ways China's CCP is illegally stealing the rest of the world blind in every area of high technology. Yes Wuhan's lab is there too. It is shocking. Houston, we have a problem. Everyone needs to see this.

 

From Reuters

 

 

 

[Krataiboy]

13 hours ago, Eric Loh said:

Certainly overdue for some positive development on the vaccine front and also hope that if successful, it will be a global sharing response to the production and proliferation devoid of geo-politics brinkmanship and self serving politics.  

The last thing we need is another dodgy vaccine rushed to market with without proper safety tests to line Big Pharma's already-bulging, taxpayer-subsidised pockets.

 

And especially not a groundbreaking RNA based variety, with the potential risk of a dangerous autoimmune reaction, or DNA shots which may permanently change an individual's genetic makeup. 

 

By the time a safe COVID 19 vaccine becomes available, there may well be too many strains of the  fast-mutating SARS 2 virus for it to prove anything other than partially effective, and in any case the pandemic itself could well be on its last legs.

 

For these reasons and the older people most at risk from COVID do not respond well to vaccines, the decision whether or not to have the shots should be at the discretion of the individual, not mandated by government or corporate sources.

 

https://needtoknow.news/2020/03/jon-rappoport-explains-the-dangers-of-experimental-dna-and-rna-vaccines-for-the-coronavirus/

 

https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-vaccine/art-20484859

 

[Bluespunk]

Synchronicity 

 

https://www.theguardian.com/world/2020/jul/07/jair-bolsonaro-coronavirus-positive-test-brazil-president?CMP=Share_iOSApp_Other

[yuyiinthesky]

15 hours ago, webfact said:

China's Sinovac Biotech is starting Phase III trials of its potential coronavirus vaccine in Brazil,

Why in Brazil, why not in China? Too risky to test in your own country?

[johnpetersen]

2 hours ago, yuyiinthesky said:

Why in Brazil, why not in China? Too risky to test in your own country?

No. Because in Brazil there are plenty of covid-19 patients to test thanks to the dismal performance of its president. In China, there just aren't enough. China isn't the only country facing that problem:

Coronavirus vaccine developers have a ‘bizarre’ problem. There’s not enough sick people.

June 11, 2020 at 1:51 a.m. GMT+7

 

 The top teams rushing to develop coronavirus vaccines are alerting governments, health officials and shareholders that they may have a big problem: The outbreaks in their countries may be getting too small to quickly determine whether vaccines work.

A leader of the Oxford University group, one of the furthest ahead with human trials, admits the reality is paradoxical, even “bizarre,” but said the declining numbers of new infections this summer could be one of the big hurdles vaccine developers face in the global race to beat down the virus.

Even as new cases are growing worldwide, transmission rates are falling in Britain, China and many of the hardest-hit regions in the United States — the three countries that have experimental vaccines ready to move into large-scale human testing in June, July and August.

https://www.washingtonpost.com/world/europe/coronavirus-vaccine-trials-astrazeneca-moderna/2020/06/09/48f28fea-a414-11ea-898e-b21b9a83f792_story.html

[Benmart]

12 hours ago, Eric Loh said:

When that polarizing world leader leader is voted out in November and leave office in January, there will be better unity in dispensing the vaccine. 

Such an election has no relevance to the story at hand. Refocus.

[metisdead]

A post using content from an unapproved YouTube source has been removed:

 

18) Social Media content is not to be used as  source material unless it is from a recognized or approved news media source,  the source of any such material (Twitter, Facebook, YouTube  etc.) should always be shown.

 

A troll post has been removed. 

[yuyiinthesky]

8 hours ago, johnpetersen said:

Coronavirus vaccine developers have a ‘bizarre’ problem. There’s not enough sick people.

This must be fake news. I see article after article about a second wave everywhere, recently Bill Gates himself again announced millions of deaths in Africa.
 

Unless you claim that these are fake news?

[johnpetersen]

2 minutes ago, yuyiinthesky said:

This must be fake news. I see article after article about a second wave everywhere, recently Bill Gates himself again announced millions of deaths in Africa.
 

Unless you claim that these are fake news?

But not in China. Or in Europe. In the USA now there plenty. But no so long ago it looked like Covid was on the decline.Let me remind you of which comment of yours I was replying to:

So what has China got to do with the rise of cases in Africa? Is China now claiming sovereignty over that continent?

 

[yuyiinthesky]

On 7/8/2020 at 1:46 PM, johnpetersen said:

But not in China. Or in Europe. In the USA now there plenty. But no so long ago it looked like Covid was on the decline.Let me remind you of which comment of yours I was replying to:

So what has China got to do with the rise of cases in Africa? Is China now claiming sovereignty over that continent?

 

You might be on to something, there a lot's of big Chinese investment in Africa, so this might be indeed be coming.

Back to the vaccine, and testing it, as far as I know you vaccine the healthy, not the sick. A vaccine is to help the healthy to not get sick. 

After you gave your new vaccine to healthy test subjects, you infect them and see if they get sick, or not.

Astonishingly there is a lot of confusion between vaccines and treatments even in the press. Nevertheless, you vaccine healthy people, and even according to you there are plenty in China. Then you try to infect them, so you need a virus, and I assume China has plenty of it, as you might know it was in Wuhan, China, where this virus started its journey. 

In any case, with this short development time, any vaccine did not go through the usual analysis and testing, to make sure they are not harmful, not damaging more than they help, not having too many side effects - a process which takes years. Therefore testing it now already it is a high risk for the test subjects. So why do Chinese pharmaceutical companies test in Brazil and US Companies (Novavax) in Australia?