Sinovac and AstraZeneca vaccines producing high antibody levels – SICRES

[webfact]

 

The immune response in those inoculated with either the Sinovac or AstraZeneca COVID-19 vaccines produce high levels of antibodies, similar to those in people who have recovered from the infection, according to Siriraj Institute of Clinical Research (SICRES).

 

The institute disclosed yesterday (Thursday) the results of its research into immune response and safety of vaccines, conducted among medical personnel at Siriraj Hospital who received either Sinovac or AstraZeneca inoculations.

 

The initial results show that, 3-4 weeks after receiving the first jab of AstraZeneca, the level of antibodies in all volunteer vaccine recipients is as high as that of an infected patient who has recovered from the disease, while 75% of those given the first dose of Sinovac have as many antibodies as the recovered.

 

Full story: https://www.thaipbsworld.com/sinovac-and-astrazeneca-vaccines-producing-high-antibody-levels-sicres/

 

-- © Copyright Thai PBS 2021-05-28

 

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[mikebell]

'research on 1,366 people shows that' with a small sample you can prove anything.

[Fromas]

Tired of all the armchair professors.

[EricTh]

Thailand is being objective rather than relying on western countries which might be biased towards certain vaccines.

 

It's good to have your own studies but what about reporting the side-effects?

 

Temporary fever, arm ache, arm numbness are to be expected. What I mean is blood clots, deaths and serious side effects.

[rabas]

48 minutes ago, webfact said:

3-4 weeks after receiving the first jab of AstraZeneca, the level of antibodies in all volunteer vaccine recipients is as high as that of an infected patient who has recovered from the disease, while 75% of those given the first dose of Sinovac have as many antibodies as the recovered.

 

So, AstraZeneca at 100% is significantly better than Sinovac at 75%, at least according to this test.

 

Because AZ is already 100%, there is no way to know how much stronger AZ is relative to Sinovac. Even if you keep increasing AZ's antibody levels, you remain at 100% of recovered patients.

 

A suspicious way to compare vaccines compared to objective Western methods.

[Isaan sailor]

Gotta pump up the Chinese vax as well as the home made AstraZeneca.  That’s all we’re left with...

[CALSinCM]

All of these local studies now promoting the local AZ and Coronav vaccines as being good as gold in the face of other studies globally.

Given the conflicts of interests literally starting right at the top and supported by webs of interconnections within Thai institutions - I don't believe a word of it.

This is not a time (global pandemic) to have conflicts of interest of such glaring magnitudes in the manufacturing, testing, regulation, and distribution of vaccines. 
And yet here we are.

[CALSinCM]

4 hours ago, Fromas said:

Tired of all the armchair professors.

Close your eyes and don't look.
Try the Farang Pub - fun, entertainment and Expat life forums.  Must lighter content.

Edited May 28, 2021 by CALSinCM

[ALLSEEINGEYE]

And other studies seem to show that both of these vaccines have very limited effect against certain variants. AZ is as low as 10.4% effective against certain variants, yet they do not seem eager to report those findings here.

 

 

 

[CALSinCM]

4 hours ago, EricTh said:

Thailand is being objective rather than relying on western countries which might be biased towards certain vaccines.

 

It's good to have your own studies but what about reporting the side-effects?

 

Temporary fever, arm ache, arm numbness are to be expected. What I mean is blood clots, deaths and serious side effects.

I doubt you'll ever see a adverse reaction database with a public-facing web portal in Thailand such as the VEARS system in the US and the Yellow-card system in the UK.
 

[Pattaya Spotter]

15 minutes ago, CALSinCM said:

All of these local studies now promoting the local AZ and Coronav vaccines as being good as gold in the face of other studies globally.

Given the conflicts of interests literally starting right at the top and supported by webs of interconnections within Thai institutions - I don't believe a word of it.

This is not a time (global pandemic) to have conflicts of interest of such glaring magnitudes in the manufacturing, testing, regulation, and distribution of vaccines. 
And yet here we are.

The AZ vaccine was to have been the main arrow in the EU's quiver against the pandemic...I hardly think they would have chosen an unsafe or ineffective one. 

Edited May 28, 2021 by Pattaya Spotter

[friendofthai]

4 hours ago, rabas said:

So, AstraZeneca at 100% is significantly better than Sinovac at 75%, at least according to this test.

Because AZ is already 100%, there is no way to know how much stronger AZ is relative to Sinovac. Even if you keep increasing AZ's antibody levels, you remain at 100% of recovered patients.

In addition to antibody levels, it is also important to consider their quality in the prevention of disease.
What did they say about the quality?
"Meanwhile, Asst. Prof. Dr. Chayanon Phucharoen, of the Faculty of Hospitality and Tourism at Prince of Songkhla University’s Phuket campus, said that research on 1,366 people shows that those who received two doses of the Sinovac vaccine have an 84% lower chance of getting infected by COVID-19"
"After the second dose of Sinovac, the level of antibodies will be as high as that of those who have recovered from an infection, according to SICRES."

So we know that the quality of the Chinese vaccine is very high. But what about the British one? Maybe the professor prefer not to show the resulting numbers in order to not hurt the feelings of those who prefer the British vaccine. His institute has published such a traumatic information already: "SICRES said, however, that more incidence of side effects were found among those under 30 who received the AstraZeneca vaccine."

Edited May 28, 2021 by friendofthai

[Tony125]

Published online in the Journal of the American Medical Association

 

Study:    Sinopharm COVID-19 vaccines appear safe, effective

 

https://www.msn.com/en-us/health/medical/study-sinopharm-covid-19-vaccines-appear-safe-effective/ar-AAKry9r?li=BBnb7Kz

[Fromas]

5 hours ago, rabas said:

A suspicious way to compare vaccines

 

What part of "first jab" escaped your notice?


 

52 minutes ago, CALSinCM said:

Close your eyes and don't look.
Try the Farang Pub - fun, entertainment and Expat life forums.

 

No, spammers of Thai-bashing conspiracy theories and dumb rumors should go there. This is the news section.

[jacko45k]

5 hours ago, EricTh said:

Thailand is being objective rather than relying on western countries which might be biased towards certain vaccines.

Do you think so.... many feel there is a China vaccine commitment?

[mtls2005]

Well that is convenient.

 

Both vaccines used here work brilliantly. And a single dose is sufficient.

 

That worked out well.

 

 

[eisfeld]

27 minutes ago, Tony125 said:

Published online in the Journal of the American Medical Association

 

Study:    Sinopharm COVID-19 vaccines appear safe, effective

 

https://www.msn.com/en-us/health/medical/study-sinopharm-covid-19-vaccines-appear-safe-effective/ar-AAKry9r?li=BBnb7Kz

 

That is a different vaccine not available in Thailand. China exports Sinopharm and Sinovac. Thailand received Sinovac.

[Lemonltr]

NHS data in the UK is more reliable as its based on factual experience of almost 6 months and almost 40 million first doses. Astra Zenica vaccine has been the bulwark and daily deaths in the similar size population are single figures. 

[rabas]

25 minutes ago, Fromas said:

What part of "first jab" escaped your notice?

 

Maybe you're not aware that many including myself plan to use AZ/sinoxxx only for a quick first dose, then wait for a top quality mRNA vaccine when available. So you will want the strongest first dose, which is clearly AZ from the study.

 

[Isaan sailor]

46 minutes ago, Tony125 said:

Published online in the Journal of the American Medical Association

 

Study:    Sinopharm COVID-19 vaccines appear safe, effective

 

https://www.msn.com/en-us/health/medical/study-sinopharm-covid-19-vaccines-appear-safe-effective/ar-AAKry9r?li=BBnb7Kz

Curious that they tested 85% men, and most of them were young men.  Not the most accurate test...

[Lemonltr]

No patient Indian variant data is available as its very recent. Huge rise in Bolton has shown that most patients were unvaccinated. None with 2 jabs but some not serious with 1. Now a race to give 2nd doses. Porton Down lab showed high post 2. protection

[mtls2005]

28 minutes ago, eisfeld said:

 

That is a different vaccine not available in Thailand. China exports Sinopharm and Sinovac. Thailand received Sinovac.

 

 

Sinopharm was approved today by the Thai FDA. Application was made on Monday.

 

https://www.reuters.com/article/health-coronavirus-thailand-sinopharm-idUSL3N2NF14L

 

Amazing how sometimes things can be done quickly here.

 

 

 

I'm sure you're aware of the Sinopharm kerfuffle, re: Chulaborn Royal Academy?

 

Chulabhorn Royal Academy to import, sell Covid-19 vaccine

 

https://www.nationthailand.com/in-focus/40001346

 

 

 

 

Edited May 28, 2021 by mtls2005

[Lemonltr]

1 hour ago, Pattaya Spotter said:

The AZ vaccine was to have been the main arrow in the EU's quiver against the pandemic...I hardly think they would have chosen an unsafe or ineffective one. 

The AZ vaccine showed high protection but took longer than Pfizer in building antibodies.. 

The issue has not been level of protection but very small proportion of blood clotting. 

[Fromas]

6 hours ago, rabas said:

A suspicious way to compare vaccines compared to objective Western methods.

 

My reaction was to this. Suspicious, subjective non-Western study alert!

 

Criticize and dispute the results all you want but use science and hold the racism.

 

 

[Lemonltr]

Anyone interested in Sinopharm should look up recent outbreaks in Chile and Seychelles. These countries used this vaccine extensively. 

[placnx]

6 hours ago, rabas said:

 

So, AstraZeneca at 100% is significantly better than Sinovac at 75%, at least according to this test.

 

Because AZ is already 100%, there is no way to know how much stronger AZ is relative to Sinovac. Even if you keep increasing AZ's antibody levels, you remain at 100% of recovered patients.

 

A suspicious way to compare vaccines compared to objective Western methods.

I think that the antibody levels are numerically measured. Two doses of mRNA vaccines produce more antibodies than a person who recovered from Covid, i.e. greater than 100%. In fact. someone who recovered from Covid and got one jab has quite high levels of antibodies. This should be in Lancet or NEJM.

[Joinaman]

1 hour ago, Tony125 said:

Published online in the Journal of the American Medical Association

 

Study:    Sinopharm COVID-19 vaccines appear safe, effective

 

https://www.msn.com/en-us/health/medical/study-sinopharm-covid-19-vaccines-appear-safe-effective/ar-AAKry9r?li=BBnb7Kz

I like that word  "Appears" but not enough to risk my life on it , 

[Crossy]

Did Sinovac get WHO approval, should have been announced today?

[rabas]

50 minutes ago, placnx said:

I think that the antibody levels are numerically measured. Two doses of mRNA vaccines produce more antibodies than a person who recovered from Covid, i.e. greater than 100%. In fact. someone who recovered from Covid and got one jab has quite high levels of antibodies. This should be in Lancet or NEJM.

 

Here is one report on a recent Spanish study, the linked presentation is also in Spanish.

 

Nature: Mix-and-match COVID vaccines trigger potent immune response

 

It appears that mRNA vaccines give a very strong boost after an initial AZ dose.  (So my 'plan' is working! Except ... where is the initial AZ dose? ).

 

Edit, I see they are giving the mRNA vaccine 8 weeks after the initial AZ dose, so that is a good number to know.

 

Edited May 28, 2021 by rabas

[Rimmer]

Troll post removed