Thailand to start human trials on COVID-19 shots via nasal spray

[snoop1130]

FILE PHOTO: People wearing protective masks queue outside the Central Vaccination Center as Thailand opens walk-in first dose of the AstraZeneca coronavirus disease (COVID-19) vaccination scheme for elders, people with a minimum weight of 100 kilograms and pregnant women amid the COVID-19 outbreak in Bangkok, Thailand, July 22, 2021. REUTERS/Chalinee Thirasupa

 

BANGKOK (Reuters) - Two coronavirus vaccines administered using a nasal spray being developed in Thailand are due to start human trials by the end of this year, after promising results in trials involving mice, a government official said on Wednesday.

 

Developed by the National Center for Genetic Engineering and Biotechnology, the vaccines are based on the adenovirus and influenza, deputy government spokeswoman Ratchada Thanadirek said.

 

After conducting trials in mice, the first phase of human trials should start by the end of this year, pending approval from the food and drug regulator, she said.

 

The trials will also test protection against the Delta variant, Ratchada said, with the second phase due in March next year and a target of production for wider use in mid-2022, if results are good, she said.

 

Research has been going on in countries around the world to develop nasal sprays to help prevent and treat COVID-19, particularly given that the lining of the nose has been identified as a key entry point for the virus.

 

Thailand's other homegrown vaccines, Chulalongkorn University’s mRNA vaccine and an inactivated virus being developed by Mahidol University, are due to start second-phase human trials this month.

 

Thailand’s vaccination campaign has so far relied on China’s Sinovac, AstraZeneca and Sinopharm shots. Pfizer/BioNTech vaccines are being given as a third booster shot for frontline medical workers who had received two doses of Sinovac.

 

Health Minister Anutin Charnvirakul said on Wednesday 32.5 million doses of the Pfizer/BioNTech vaccine should be delivered this year, made up of an order of 30 million doses and donated shots from the United States.

 

About 6.8% of Thailand's population of more than 66 million people have received two doses of a vaccine.

 

-- © Copyright Reuters 2021-08-11

 

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[Scrotobike]

Do YOU take it up the nose my dear?

[Tropicalevo]

Wasn't there a Prime Minister who recently said that he would not allow Thai people to be used as guinea pigs?

[Tarteso]

13 hours ago, snoop1130 said:

to start human trials by the end of this year,

They don’t even know if it will rain tomorrow…. And with 6% of the population vaccinated

Edited August 12, 2021 by Tarteso

[jacko45k]

12 hours ago, Scrotobike said:

Do YOU take it up the nose my dear?

Dare I say it has been developed for that Issarn feature?

[Srikcir]

Will Siam Bioscience be the company to produce the spray? 

[vandeventer]

13 hours ago, Tropicalevo said:

Wasn't there a Prime Minister who recently said that he would not allow Thai people to be used as guinea pigs?

Guinea Pigs are getting harder and harder to find, politicians maybe next in line. 

[Burma Bill]

18 hours ago, snoop1130 said:

using a nasal spray being developed in Thailand

Quoted from wikipedia:-

Ring-a-ring o' roses,
A pocket full of posies,
A-tishoo! A-tishoo!
We all fall down.^[3]

[sawadee1947]

18 hours ago, snoop1130 said:

received two doses of a vaccine.

That doesn't mean anything. 

Important is being vaccinated with effective vaccines but not with that Chinese <deleted>. 

[bluebluewater]

Is any other country in the world chasing a nasal spray type of vaccine?  I'm unaware of it if so.  Pills are possibility and there are labs looking into that end.  Nasal spay seems a bit out there.

[Meat Pie 47]

13 minutes ago, bluebluewater said:

Is any other country in the world chasing a nasal spray type of vaccine?  I'm unaware of it if so.  Pills are possibility and there are labs looking into that end.  Nasal spay seems a bit out there.

Australia has been doing it for a while

https://www.abc.net.au/news/2021-07-16/covid-19-nasal-spray-could-help-plug-gaps-in-vaccine-roll-out/100298438

[placeholder]

1 hour ago, bluebluewater said:

Is any other country in the world chasing a nasal spray type of vaccine?  I'm unaware of it if so.  Pills are possibility and there are labs looking into that end.  Nasal spay seems a bit out there.

"Of the approximately 100 COVID-19 vaccines currently undergoing clinical trials, however, only seven are nasal sprays. And all COVID-19 vaccines currently approved for use are delivered via intramuscular injection."

https://www.healthline.com/health-news/why-some-experts-think-nasal-sprays-are-the-best-approach-for-covid-19-vaccines#A-different-type-of-immune-response