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New treatment(Psilocybin, Ketamine etc) for depression in LOS


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Posted

Are there any clinics, hospitals in Thailand that make these drugs/treatments available to patients suffering from depression /anxiety in Thailand?

Several studies have shown that psychedelics can bring an immediate and significant improvement in these conditions, in marked contrast to the SSRI ,which take time to work, if they work at all , and which you have to take indefinitely. 

Even in the west they are still kind of experimental, but more and more psychiatrists are coming around, and see these drugs as the future. 

As the cannabis legalization has shown, sometimes Thailand is at the forefront of novel approaches.

 

  • Haha 1
Posted
4 minutes ago, Celsius said:

 

You are kidding, right?

It all about what you want to believe or not. Strong beliefs can move mountains, still there is some evidences that might leads someone to believe there is wonderdrugs solving all their problems.

 

Well, studies shows at temporary positive results 

Posted
20 minutes ago, Celsius said:

 

You are kidding, right?

Sort of ,one step forward, two steps back.

I enjoyed the 2 years of the forward step.

With the Shinawatras, of course, it's always back ,at least in the fun department. 

  • Confused 1
Posted
17 minutes ago, Hummin said:

It all about what you want to believe or not. Strong beliefs can move mountains, still there is some evidences that might leads someone to believe there is wonderdrugs solving all their problems.

 

Well, studies shows at temporary positive results 

Nothing  other than death, is solving all your problems. 

A strong placebo effect is present in all psychiatric treatment. Randomized double blind trials would be needed to sort out how much of it is Placebo. 

Posted
8 hours ago, thecyclist said:

Are there any clinics, hospitals in Thailand that make these drugs/treatments available to patients suffering from depression /anxiety in Thailand?

Several studies have shown that psychedelics can bring an immediate and significant improvement in these conditions, in marked contrast to the SSRI ,which take time to work, if they work at all , and which you have to take indefinitely. 

Even in the west they are still kind of experimental, but more and more psychiatrists are coming around, and see these drugs as the future. 

As the cannabis legalization has shown, sometimes Thailand is at the forefront of novel approaches.

 

 

Every time there is a a potential use of a  drug for a specific type of symptom, it is often presented as having  much broader and more effective properties than have been demonstrated.   Yes, some types of psychedelic drugs, such as psilocybin  have shown the POTENTIAL as therapies for treatment of a small number of  patients with very specific manifestations of their illness. To date, the evidence is NOT conclusive.

 

Depression includes a large number of causes, some organic in cause and others behavioural.  To date, only two types of depression have  been documented to show potential:  PTSD (post-traumatic stress disorder) and drug resistant  treatments.  The use for PTSD  is the least likely to show potential benefit and it is believed that there may be an underlying emotional disorder that is involved, i.e. that the issue is not PTSD  itself, rather that the PTSD is a symptom of the underlying issue.

 

More and more psychiatrists are not "coming around".  There has long been an openness to consider alternatives to treatment resistant therapies, provided that they are demonstrated as safe and effective. To date, the evidence is not there. If and when the clinical trials show that it helps, then it can become another tool in the treatment of mental illness.

 

Every drug has a side effect. Some are negative, some are positive, but a drug by its very function changes the body's chemistry and impacts the chemical reactions in the body. Psychedelics can be very potent and have the potential for  misuse with serious consequences. Learn from the opioid crisis. When Oxycontin was first introduced, it was praised as the ultimate in pain relief. Prescriptions flew off the desk of prescribing physicians.  People with chronic pain sang its praises. The rest is history. It wasn't the first time either. We saw it with the use of anxiolytics. Pop a pill and anxiety was  "cured".  It didn't work out quite that way for some users turning them into emotionless zombies.

 

Psychedelics can only be used for the treatment of a select group of patients because of the adverse reactions that include  dizziness, drowsiness, extreme dissociation from reality, panic attacks, and nausea. Giving the drug to  patients with a concurrent mental illness like bipolar state or schizophrenia or pre-existing brain damage (e.g.  fetal alcohol syndrome) can  be deadly to both the patient and to others, provoking an emotional  unstable emotional state.

 

 

How about waiting until; 1. The psychedelic drug benefit is established, and 2. Identifying which illness it is best suited for, before  promoting its benefits?

 

 

 

 

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Posted

Psilocybine is illegal in Thailand. No exceptions for medicsl use.

 

Ketamine is a schedule 2 psychotropic and apprived only for anesthedia. AFAIK you will not find it used for depression in Thailand.

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Posted

"In an era where film stars led closely-guarded private lives and studios were vigilant in protecting the images of their biggest names, Grant had no reservations about professing his love for psychedelic drugs. Treating it as therapy in part for unresolved issues concerning his mother, Grant took LSD weekly in 1958 and may have had as many as 100 trips; he referred to his subsequent enlightenment as a “rebirth” and “unscrewing myself.” Grant's use of LSD reportedly persuaded Timothy Leary to experiment with it."

 

Grant professed that he had severe depression related to his father committing his mother to a mental institution without telling young Grant. Grants indulgence in LSD helped him cope with this depression, so he said.

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