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WHO sees 'potentially positive data' on COVID-19 treatments


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WHO sees 'potentially positive data' on COVID-19 treatments

 

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FILE PHOTO: A logo is pictured on the headquarters of the World Health Organization (WHO) ahead of a meeting of the Emergency Committee on the novel coronavirus (2019-nCoV) in Geneva, Switzerland, January 30, 2020. REUTERS/Denis Balibouse

 

GENEVA (Reuters) - The World Health Organization said on Tuesday that some treatments appear to be limiting the severity or length of the COVID-19 respiratory disease and said the body is focusing on learning more about four or five of the most promising ones.

 

“We do have some treatments that seem to be in very early studies limiting the severity or the length of the illness but we do not have anything that can kill or stop the virus,” spokeswoman Margaret Harris told a virtual briefing, referring to the body’s so-called Solidarity Trial of drugs against the disease.

 

“We do have potentially positive data coming out but we need to see more data to be 100% confident that we can say this treatment over that one,” she added.

 

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-- © Copyright Reuters 2020-05-12
 
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A post with a link to a Conspiracy-Pseudoscience site has been removed. 

 

Posts with videos from unapproved YouTube sources have been removed,  clips from movies are not a credible source of information:

 

18) Social Media content is not to be used as  source material unless it is from a recognized or approved news media source,  the source of any such material (Twitter, Facebook, YouTube  etc.) should always be shown.

 

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the money would be behind a treatment or vaccine that worked which is why all these suspicions of international cabals seem like paranoid nonsense to me. anyone who has actually worked in an international org can attest that they are too inefficient and working at cross purposes to carry out some dastardly plan.. oy..

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The real key to this is controlled comparative double-blind studies in matched populations. The problem is how do you do this when the virus manifests itself in so many different way in different people. We also need comparative studies but the Pharma industry doesn't ever want to do comparative studies because their drug may lose, and even if they design a non-inferiority trial, the numbers mat look bad for them. From a statistical quirk, non inferiority studies are much larger and much more expensive than effectiveness comparisons. 

The basic problem is that the US regulatory system only requires efficacy to be shown vs placebo, not against an active treatment. Given the myriad treatment options that everyone and his dog (Trump) are touting as miracle cures based on no evidence, it is difficult to find any comparator regimen.

The approval of Gilead's drug was not based on efficacy but time to recovery. The end point of the trial was not specified in the original protocol and was made up after the data had been seen by statisticians. This is a flawed analysis....no one can change endpoints after seeing the data. The FDA should never have approved the treatment. I do hope they have required more studies to be conducted. 

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1 hour ago, Pedrogaz said:

The real key to this is controlled comparative double-blind studies in matched populations. The problem is how do you do this when the virus manifests itself in so many different way in different people. We also need comparative studies but the Pharma industry doesn't ever want to do comparative studies because their drug may lose, and even if they design a non-inferiority trial, the numbers mat look bad for them. From a statistical quirk, non inferiority studies are much larger and much more expensive than effectiveness comparisons. 

The basic problem is that the US regulatory system only requires efficacy to be shown vs placebo, not against an active treatment. Given the myriad treatment options that everyone and his dog (Trump) are touting as miracle cures based on no evidence, it is difficult to find any comparator regimen.

The approval of Gilead's drug was not based on efficacy but time to recovery. The end point of the trial was not specified in the original protocol and was made up after the data had been seen by statisticians. This is a flawed analysis....no one can change endpoints after seeing the data. The FDA should never have approved the treatment. I do hope they have required more studies to be conducted. 

This is why we realistically are looking at 2 years or longer for a vaccine (if ever).  It’s hard to imagine that a treatment to kill the virus can be available on a 6-9 month timetable that people have been speaking about.  

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4 hours ago, Harveyg said:

I have no idea what was removed and it may be legitimate. It is like to point out:  If there’s corruption Or collusion in the CDC or the WHO and FB and YouTube go along with it.    then....   and how many peer reviewed research that support these banned claims are necessary?  Oh wait.  You may never see them unless you know where to look. Who runs the WHO?   Follow the money!!  Sometimes it’s money talking not science. 

China owns WHO 

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1 hour ago, candide said:

You have absolutely no idea of what the WHO is and how it works. The WHO is not a stand alone organisation, it is staffed by people sent by the different national governments. Decision making is based on committee recommendations, and the most important ones are composed of members of the respective national health organisations.

The highest one, the executive board, is composed of 34 members, and there Isn't a pro-China majority as you can check in the list. The chair is Japanese, a country which cannot be suspected to be pro-China. The US is represented by one of the top executives of the US Department of HHS.

Another is the health regulation emergency committee. It is composed according to the same principle and is chaired by the Head of the French health department.

The scientific teams are composed of scientist sent by their countries. National teams (i.e. CDC) also work in coordination with the WHO.

When the WHO makes a scientific statement such as this one, it means it is based on the work of US, German, French, Japanese scientist, etc...

 

But don't let facts get in the way of a good story promoted by Trump, right?

Trump off

 

While much of what you say is correct in principle, in practice the reality is often different. On the ground level UN organizations like WHO and UNDP, where I worked for a while, do a tremendous amount of unseen good particularly in the developing world. At high levels were politics and money come to play things are very different, as discussed for many years.

 

Here is an introduction to some of the money and corruption problems facing the WHO before the current problems. Not to mention Chinese manipulation of UN operations through their involvement in Ethiopia. (You can research that through wiki)

 

https://www.abc.net.au/news/2020-02-17/coronavirus-who-underfunded-internal-corruption-allegations/11970382


https://www.nationalreview.com/2017/06/world-health-organization-corrupt-wasteful/

 

Why the Corruption of the World Health Organization (WHO) is the Biggest Threat to the World’s Public Health of Our Time (2015)


Trump on

 

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If WHO was to be disbanded tomorrow, countries would rush to set up a new org. No man-made institution is perfect and corruption lurks everywhere (except maybe in Trumpland, the new paradise on earth) but those institutions have to be judged on the work they do and one should ponder on what would happen if they did not exist?

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https://uk.news.yahoo.com/video/italy-trials-coronavirus-smart-helmet-061333098.html

 

Italy trials new coronavirus 'smart helmet'

7be4a340-af8a-11e9-a777-82ed94432593
PA Media: Video13 May 2020

Engineers at Rome's Fiumicino Airport were testing a new 'smart helmet' on Tuesday which allows passengers' temperatures to be scanned while they're moving, as part of a series of safety measures to protect people from Covid-19 when flights resume.

The helmet can tests people's temperatures within a seven-metre radius.

 
 
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2 hours ago, rabas said:

Trump off

 

While much of what you say is correct in principle, in practice the reality is often different. On the ground level UN organizations like WHO and UNDP, where I worked for a while, do a tremendous amount of unseen good particularly in the developing world. At high levels were politics and money come to play things are very different, as discussed for many years.

 

Here is an introduction to some of the money and corruption problems facing the WHO before the current problems. Not to mention Chinese manipulation of UN operations through their involvement in Ethiopia. (You can research that through wiki)

 

https://www.abc.net.au/news/2020-02-17/coronavirus-who-underfunded-internal-corruption-allegations/11970382


https://www.nationalreview.com/2017/06/world-health-organization-corrupt-wasteful/

 

Why the Corruption of the World Health Organization (WHO) is the Biggest Threat to the World’s Public Health of Our Time (2015)


Trump on

 

Quite interesting comment and sources, but that does not relate to my post. I never claimed the way the WHO is/was working was perfect. It was not even addressing this issue. 

 

My claim was that so-called reputable countries such as the US, Japan, Germany, France, Australia etc... are directly involved in the management and decision-making of WHO through members of their national administrations. And it's not like the European Commission, where members have to quit their national positions. At the WHO, members of key committees still hold their domestic position. The US member of the executive board is still holding her position at the US Department of HHS, the chair of the emergency committee is still the head of the French health administration, etc..

My other observation is that, when one looks at the composition of the board and emergency committee, it does not seem there is a majority of countries under Chinese influence.

 

BTW, I have been quite interested by your first source showing that the World Health Organisation division leading the global response to the coronavirus outbreak was underfunded.

But hey! It's the perfect time to halt WHO funding, right?

Trumping on! ????

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