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U.S. man is oldest person possibly cured of HIV after stem cell transplant


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A 66-year-old man is the oldest person yet to possibly be cured of HIV after undergoing a stem cell transplant, researchers announced Wednesday.

 

The man had HIV for more than 31 years when he received a blood stem cell transplant in early 2019 for acute myeloid leukemia (AML) using cells from a donor with a rare genetic mutation that prevents HIV from entering human cells, making people who have it resistant to most strains of the virus.

 

The man has remained free of replicating HIV since his transplant — including for the last 17 months after stopping treatment for HIV, said Jana K. Dickter, MD, a physician at City of Hope National Medical Center in Duarte, California, where the patient was treated.

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He is at least the fourth person to have potentially been cured of HIV after receiving stem cells from someone with the CCR5-delta 32 mutation, and the second such case to be made public this year.

 

(more)

 

https://www.healio.com/news/infectious-disease/20220727/man-is-oldest-person-possibly-cured-of-hiv-after-stem-cell-transplant

 

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