A Dengue Fever Vaccine for Thailand is just around the corner

[snoop1130]

A Dengue Fever Vaccine for Thailand is just around the corner

BANGKOK -- As the Ministry of Public Health expect Dengue Fever cases to grow by over 16 percent this year, news has broke that a new vaccine against the virus is now on the path to registration in Thailand.

The Food and Drugs Administration is currently considering registration of the vaccine against four different strains of the virus, said Jarung Muangchana, director of the National Vaccine Institute.

“If the vaccine registration is approved, it will gain acceptance for legal use nationwide,” he said.

This vaccine has already been registered in the Philippines, Mexico and Brazil, reports the Bangkok Post, and although is proven to only be 60 percent effective, is still an important tool in the fight against Dengue.

In the cases where the vaccine did not work in completely eliminating Dengue, 80 percent of patients still saw its virility lessened.

Full Story: http://whatsonsukhumvit.com/a-dengue-fever-vaccine-for-thailand-is-just-around-the-corner/

-- (c) What's on Sukhumvit 2016-02-18

[OOLEEBER]

This is HUGE if it's true.

[Sheryl]

It's true.

[jacky54]

whoever developed that should get the Nobel prize

[Koolhand]

Somewhat off topic... relevant all the same

[Pakaty]

I hope this is not from the same people that brought us the cure for ebola.

[bubblegum]

bs

[inaktive]

Somewhat off topic... relevant all the same

Zika is around for at least 60 Years but as long as it was only Africa and other poor Places noone in the Media cared.

Doesnt mean the Pharma companies didnt see that outbreak coming because it was spreading for years now.

Everyone who works in Pharma did see it jump from africa to asia and micronesia and then to south america.

it was just a question of when it would reach countries wealthy enough so a vaccine will make money.

https://en.wikipedia.org/wiki/Zika_virus

now that its at the US Border its all bit Media frenzy but even a year ago when it was already running crazy in many places like Brasil the media didnt care.

[sunnyjim5]

What is being discussed is Dengvaxia

http://www.sanofipasteur.com/en/articles/dengvaxia-world-s-first-dengue-vaccine-approved-in-mexico.aspx

[thedemon]

Somewhat off topic... relevant all the same

Zika is around for at least 60 Years but as long as it was only Africa and other poor Places noone in the Media cared.

Doesnt mean the Pharma companies didnt see that outbreak coming because it was spreading for years now.

Everyone who works in Pharma did see it jump from africa to asia and micronesia and then to south america.

it was just a question of when it would reach countries wealthy enough so a vaccine will make money.

https://en.wikipedia.org/wiki/Zika_virus

now that its at the US Border its all bit Media frenzy but even a year ago when it was already running crazy in many places like Brasil the media didnt care.

Why didn't you fund it last year?

[torpedo1970]

sure.... as they cured Ebola they are the best!!!

after all

TIT

[inaktive]

Somewhat off topic... relevant all the same

Zika is around for at least 60 Years but as long as it was only Africa and other poor Places noone in the Media cared.

Doesnt mean the Pharma companies didnt see that outbreak coming because it was spreading for years now.

Everyone who works in Pharma did see it jump from africa to asia and micronesia and then to south america.

it was just a question of when it would reach countries wealthy enough so a vaccine will make money.

https://en.wikipedia.org/wiki/Zika_virus

now that its at the US Border its all bit Media frenzy but even a year ago when it was already running crazy in many places like Brasil the media didnt care.

Why didn't you fund it last year?

You know they are working on the Zika Vaccine for years already thats why they are nearly done ?

After 2007 all the Vaccine companies did start their research because it was just a matter of time and the first will be a megaseller.

But Vaccines take a lot of time to design and test.

The first Trials of Dengue Vaccines are now more than 10 yearsold and the vaccines are still not on market and perfected.

If they had one ready dont you think they would sell it and corner that market as fast as possible ? with a average of 3 doses per person needed it would be a megaseller with around 2.5 BILLION people living in countries with dengue right now. Even at a low price of say 5$ per dose thats 7.5 BILLION $ in just one year and the first can most likely charge a lot more !

And who tells you i didnt invest in that ;-)

[sunnyjim5]

inaktive

You are mistaken if you believe there is not a Dengue vaccine on the market

Dengvaxia is the name of the vaccine !

http://www.sanofipasteur.com/en/articles/dengvaxia-world-s-first-dengue-vaccine-approved-in-mexico.aspx

This is also the vaccine being evaluated by the Thai Health Authorities ( It is the first and currently the only Dengue vaccine available)

[Thechook]

whoever developed that should get the Nobel prize

nah the Thai that created the ebola vacine deserves it more, he save many lives and destroyed the ebola virus.

[Laughing Gravy]

I would say that Thailand is certainly a very good supplier of generic medicines but I will be happily surprised if they can make this vaccine and be the originators..

[chiman]

Somewhat off topic... relevant all the same

Lol the X-Files is back open

[silent]

Do you know if it wasn't actually created by a pharmaceutical company and started to spread from Guinea?

Somewhat off topic... relevant all the same

Zika is around for at least 60 Years but as long as it was only Africa and other poor Places noone in the Media cared.

Doesnt mean the Pharma companies didnt see that outbreak coming because it was spreading for years now.

Everyone who works in Pharma did see it jump from africa to asia and micronesia and then to south america.

it was just a question of when it would reach countries wealthy enough so a vaccine will make money.

https://en.wikipedia.org/wiki/Zika_virus

now that its at the US Border its all bit Media frenzy but even a year ago when it was already running crazy in many places like Brasil the media didnt care.

[The Deerhunter]

It's true.

It probably is but it was or is only approved in two places, France & Brazil I think, and then only for people between 16 & 40-something. But it sure is a start. Just no use for kids or us expat oldies who could afford it

[cumgranosalum]

Somewhat off topic... relevant all the same

Irrelevant and highly inaccurate. Remember too that correlation does not equal causation and ifact even the correlation claims here are inaccurate.

For a good rebuttal read this.

http://blogs.discovermagazine.com/science-sushi/2016/01/31/genetically-modified-mosquitoes-didnt-start-zika-ourbreak/#.VsZ2eMct_qM

[gandalf12]

Just like the HIV vaccine Thailand developed

[cumgranosalum]

It's true.

It probably is but it was or is only approved in two places, France & Brazil I think, and then only for people between 16 & 40-something. But it sure is a start. Just no use for kids or us expat oldies who could afford it

At the end of 2015 it was Philippines, Brazil and Mexico. Others are following.

Sanofi the company is French based.

It is most likely that countries with high incidence of Dengue will approve it first.

There seems also to be a massive amount of misinformation and ignorance surrounding Dengue, the Aedes mosquito and other diseases (e.g. Zika) for which this animal is a vector.

There is a lot f info out there - I can only assume that people still don't know how to get information from the internet and don't seem to be able to sift fact from fiction or conspiracy theory.

[DM07]

I will believe it, when I see it!

e.g. I don't believe it!

[cumgranosalum]

It's true.

It probably is but it was or is only approved in two places, France & Brazil I think, and then only for people between 16 & 40-something. But it sure is a start. Just no use for kids or us expat oldies who could afford it

If approved in Thailand you will probably be able get it. As for cost, so far there have been no claims that it is "too expensive". Cost to a population will also depend on how much is subsidised by respective governments

As for "no use"

I haven't seen an explanation yet for the age range that it was made available to in Brazil....I don't think it was to do with limits on efficacy, it was more based on demographic considerations.

for a vaccine to be effective it needs to be targeted on the right population.

Edited February 19, 2016 by cumgranosalum

[irwinfc]

info and results from the paper that documents the clinical trial that tested Dengvaxia (Clinical efficacy and safety of a novel tetravalent dengue vaccine in healthy children in Asia: a phase 3, randomised, observer-masked, placebo-controlled trial)

* Vaccine name: Dengvaxia

* No. of doses required: 3 doses within one year (@months 0, 6, and 12)

* Adverse events among vaccinated: 62%

* Adverse events among controls: 38%

* "The primary endpoint was achieved with 56·5% (95% CI 43·8-66·4) efficacy."

the last line means that out of 100 persons who never had dengue fever before, 56-57 of them are likely to be protected from dengue. due to the design nature of clinical trials, the statement above also means that anyone who gets vaccinated can toss a coin with the chance of head (or tail) equal to being protected from dengue. very exciting... not!

Edited February 19, 2016 by irwinfc

[sawadee1947]

...after all....Thailand is moving forward. Hope to buy it soon.

[cheeryble]

Somewhat off topic... relevant all the same

Irrelevant and highly inaccurate. Remember too that correlation does not equal causation and ifact even the correlation claims here are inaccurate.

For a good rebuttal read this.

http://blogs.discovermagazine.com/science-sushi/2016/01/31/genetically-modified-mosquitoes-didnt-start-zika-ourbreak/#.VsZ2eMct_qM

A fascinating read, thanks for that

[Siameaze]

The principal problems with a vaccine "cure" are availability, distribution and cost. The root cause still needs to be addressed. That is to minimize mosquito population. Yesterday it was malaria, then dengue and now zika. There are basic steps to still be taken in mosquito minimization and people may gain false hope from a vaccine "cure". Prevention should still be the primary activity.

[LannaGuy]

I heard they used section 44

[Siameaze]

I moved to Thailand from Singapore. They had a dengue problem a few years back. The government (basically benevolent) started a program on addressing mosquito breeding. The citizens are compliant as well as business. Lots of education on the problem and many inspections with associate fines at worksites and even residences. Looking for free standing water where the mosquitos breed. Lots of fogging carried out too. YET SINGAPORE STILL HAS A BIG DENGUE PROBLEM AND NOT WAITING FOR A VACCINE!!!! They openly provide statistics on clusters and encourage individual "self-defense".: Spray under beds and in closets; apply repellent; clear out water catching spots; contain and;remove food waste (Mosquitos love leftovers)

So this isn't an easy problem that will go away waiting for a vaccine. Strong effort is still being applied to the prevention battle but the problem is still far from over.

[Johnniey]

Thailand does something good and only a few give praise. Where are all the old moaners? Saying "tee rak Thai mosquito make better me" Maybe on the learn Thai sub forum lol.

Well done Thailand!