2nd dose of AstraZeneca COVID-19 vaccine to be given 16 weeks after 1st dose

[mtls2005]

3 hours ago, nkg said:

Delaying the 2nd dose of AZ can actually be beneficial:

 

 

Good luck selling that idea.

 

If it was beneficial why wait until yesterrday, under very murky circumstances, to pivot to a more benefical plan?

 

Will be interesting to watch the various regime mouthpieces spin this excretion into "gold" today.

[internationalism]

8 hours ago, covidiot said:

just got my first dose (moderna / not in thailand).

2nd dose is scheduled exactly in 16 weeks. 

so it's not just thailand doing this. 

thailand has only AZ, moderna might be coming only at the end of year.

 

Moderna is 28 days, not 16 weeks:

"Moderna's COVID-19 vaccine takes two doses given 28 days apart, and the Pfizer/ BioNTech COVID-19 includes two doses given 21 days apart"

https://www.nationalheraldindia.com/health/who-suggests-21-28-day-gap-between-2-pfizer-doses

[Daithi85]

2 minutes ago, internationalism said:

thailand has only AZ, moderna might be coming only at the end of year.

 

Moderna is 28 days, not 16 weeks:

"Moderna's COVID-19 vaccine takes two doses given 28 days apart, and the Pfizer/ BioNTech COVID-19 includes two doses given 21 days apart"

https://www.nationalheraldindia.com/health/who-suggests-21-28-day-gap-between-2-pfizer-doses

That Nationalherald India article is 5 months old, things have  changed since  then. 

[internationalism]

14 minutes ago, Daithi85 said:

That Nationalherald India article is 5 months old, things have  changed since  then. 

ok.

so what is the gap?

here April

"If you received the Moderna COVID-19 Vaccine, you should get your second shot 4 weeks (or 28 days) after your first."

"https://www.cdc.gov/coronavirus/2019-ncov/vaccines/second-shot.html

 

tha vax tours to the USA last only 10 days, they got pfizer and moderna.

[Poet]

37 minutes ago, mrfill said:

That's the best approach if you would like a situation like that in India.

Nonsense. If you have a fast-moving variant such as the one in India, the fact that the recommended length of time for the second shot of Pfizer or Moderna is 28 days means that a country's population will be fully-innoculated more quickly than if you give you give them AstraZeneca and have to wait 3-4 months for the second shot.

AstraZeneca may be almost as protective as the mRNA vaccines but that delay, necessary for optimal protection, is a serious problem.

I specifically said best approach and, given a choice, any epidemiologist would choose Pfizer or Moderna over Astrazeneca, mainly to avoid that delay.

[hotchilli]

11 hours ago, madmen said:

What a mess. Farang can forget about it untill the end of the year 

My monies on next year

Supplies coming from only one source that obviously cannot meet demand.

70% inoculated in 11 provinces this year, supplies will then go where?

Other provinces who are waiting or 2nd jabs...  a complete and utter farce.

[Daithi85]

10 minutes ago, internationalism said:

ok.

so what is the gap?

here April

"If you received the Moderna COVID-19 Vaccine, you should get your second shot 4 weeks (or 28 days) after your first."

"https://www.cdc.gov/coronavirus/2019-ncov/vaccines/second-shot.html

 

tha vax tours to the USA last only 10 days, they got pfizer and moderna.

According to news from  Canada all approved vaccines can  have  a 16 week gap between 1st and 2nd jab. 

[rwill]

Perhaps they are hoping the pandemic will be called over by then so they don't have to give free shots anymore.

 

 

[covidiot]

50 minutes ago, internationalism said:

 

Moderna is 28 days, not 16 weeks:

i am not in thailand, so just ignore my post.

although it does match the 16 weeks. that's why i mentioned it.

[George Aylesham]

13 hours ago, wasabi said:

It does seem AZ Vaccine has an abnormally long gap between doses but not sure about 4 months?

Not a medical decision but an attempt to meet lack of availability of AZ vaccine.

[Ganesh108]

3 hours ago, mrfill said:

That's the best approach if you would like a situation like that in India.

In many Indian villages people refuse to be vaccinated, as people died right after the jab (AstraZeneca, in India marketed under the name Covishield). 

[placeholder]

2 hours ago, Poet said:

Nonsense. If you have a fast-moving variant such as the one in India, the fact that the recommended length of time for the second shot of Pfizer or Moderna is 28 days means that a country's population will be fully-innoculated more quickly than if you give you give them AstraZeneca and have to wait 3-4 months for the second shot.

AstraZeneca may be almost as protective as the mRNA vaccines but that delay, necessary for optimal protection, is a serious problem.

I specifically said best approach and, given a choice, any epidemiologist would choose Pfizer or Moderna over Astrazeneca, mainly to avoid that delay.

The delay isn't about the most effective use of the vaccine for use by an individual. It's about limited supplies and how best to deploy them for public health. More lives will be saved if the limited supply is distributed via single doses than would be saved if that same supply were to be deployed via 2 doses given to individuals.

[mtls2005]

Seems like we're inching towards a "one dose is good enough" vaccination "plan".

 

Next stop, waving an empty AZ ampule near a patient gives 187% efficacy.

 

 

[Poet]

5 minutes ago, placeholder said:

The delay isn't about the most effective use of the vaccine for use by an individual. It's about limited supplies and how best to deploy them for public health. More lives will be saved if the limited supply is distributed via single doses than would be saved if that same supply were to be deployed via 2 doses given to individuals.

You are talking about the current situation in Thailand, in which the priority is to get at least some protection to as many people as possible. Fair enough. I am talking about what offers the "best" protection in a situation in which one shot (of any vaccine) does not offer sufficient protection to slow down a fast-moving variant.

Leaving people hanging with just one shot of protection for 12 or 16 weeks was previously considered a good plan in the UK but now, in the face of the Indian variant, they are adapting that plan, reducing the gap and, in some cases, giving a much earlier shot of Pfizer instead of AZ as the second shot.

 

[Cake Monster]

8 hours ago, webfact said:

he plan follows a similar decision by Spain to stretch the gap between two AstraZeneca doses to 16 weeks, which is beyond the 12 weeks maximum interval approved by the European Medicines Agency. A 16-week interval has not been tested in human trials.

But thinking to myself

If the second dose of AZ is delayed by an extra 6 weeks over and above the 10 weeks that was initially planned, that will give SB an extra 6 weeks to come good on the promised Vaccine doses.

[rbkk]

....and all the while I keep hearing the deafening silence from the Thailand developed vaccine. Jockeying for position? Coming up from behind at the starting gates? Who knows?

[natway09]

OK, we all got the message,,,,, another "stall" tactic !!!!

[placnx]

15 hours ago, Fromas said:

Yes, this is B.C., Canada's dosing interval: COVID-19 vaccine doses will be administered 16 weeks apart in B.C.

 

However it's a compromise that could have been avoided.

I hope that they will take careful note of the results of the 16-week interval and publish in a journal.

[placnx]

15 hours ago, Blumpie said:

More and more countries are doing this.  It's been proven that the response after 12-16 weeks is perfectly acceptable and even better than after 3 weeks.  Plus it gets more people protected.

Thailand is doing some things right.

 

13 hours ago, RichardColeman said:

16 weeks is beyond the European Medical Agency approval interval. 16 weeks has not been through medical human trials as of yet - so it's in the lap of the Gods as to it working or not.

 

But, by the time I can get on a plane to Thailand to get back to the family, I fully expect a third UK booster jab.

Jabs beyond the standard two for AZ - J&J may not be effective because the immune system attacks the adenovirus vector.

[placnx]

12 hours ago, tingtong said:

Interesting tactic trying to catch up with other countries in the vaccine race.

 

Only problem that the immune response isn't equal after shot#1 &#2, 

Will result a false sense of safety in ppl whereas by the 16th week many case the efficiency of the first shot will come very close of those village temple Buddha amulets...

How about getting a good mask and learning how to put it on properly?

Edited May 25, 2021 by placnx
wording error

[placnx]

4 hours ago, Ganesh108 said:

In many Indian villages people refuse to be vaccinated, as people died right after the jab (AstraZeneca, in India marketed under the name Covishield). 

Maybe the person giving the jab was incompetent?

[placnx]

4 hours ago, Poet said:

You are talking about the current situation in Thailand, in which the priority is to get at least some protection to as many people as possible. Fair enough. I am talking about what offers the "best" protection in a situation in which one shot (of any vaccine) does not offer sufficient protection to slow down a fast-moving variant.

Leaving people hanging with just one shot of protection for 12 or 16 weeks was previously considered a good plan in the UK but now, in the face of the Indian variant, they are adapting that plan, reducing the gap and, in some cases, giving a much earlier shot of Pfizer instead of AZ as the second shot.

 

Giving Pfizer as the second will also give preliminary data for using it as an AZ booster.

[sambum]

Basically, they haven't got enough Astro Zeneca vaccine, but waffle on with lame excuses like "so that the supply of vaccines can be distributed more widely", and  " to reflect the changing situation" (The changing situation is that they are not producing/acquiring enough to fulfil the promises made already!)