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Effectiveness of Pfizer vaccine against Omicron plummets, says Thai doctor - Sinovac study awaited

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On 12/21/2021 at 6:48 AM, placnx said:

Here's the study: https://pubmed.ncbi.nlm.nih.gov/33948601/

This is another matter, i.e. people who get vaccinated after an infection have really good immunity thereafter. If you have a breakthrough infection, I hope that a new variant on Omicron does not happen! (Of course not likely in a single case, but with very many instances of this, there's no guarantee that selection pressure will not occur). 

If omicron becomes dominant worldwide, would a new variant not have to become even more transmissible but also less deadly before it's able to take omicrons place?

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34 minutes ago, KannikaP said:

So why do places insist that you are double jabbed before you can go in?

Because we're just repeating dogma at this point.

 

I should explain that I am fully vaccinated and had a booster.

I am pro-vaccination, but it does seem like critical thinking left the building a while back.

8 minutes ago, Karma80 said:

Because we're just repeating dogma at this point.

 

I should explain that I am fully vaccinated and had a booster.

I am pro-vaccination, but it does seem like critical thinking left the building a while back.

It's really excruciatingly simple. Vaccines slow transmission.

On 12/20/2021 at 8:42 PM, Sunderland said:

What do you mean some people in developing countries haven't even had a 1st shot? What do you mean they are not getting sick and dying? Hush! 

 

Boost! Boost! You need more of this emergency "vaccine".

 

What do you mean colds,. fevers and flu are less common than 3 years ago? Hush!!!

 

 

1)Clearly you don't understand that the poorer a nation is, the worse their public health system is. That means the reporting from such countries is generally poor:

"Excess mortality rates for the developing world are much higher than what reported COVID-19 mortality data suggest: 2.5 times higher for UMICs, 12 times more for LMICs, and 35 times greater for LICs. For HICs they are practically the same—actually about 3 percent lower. To see this, compare the dashed and solid lines, which represent the population-weighted averages for each income group (see also Figure 6 for the time series).

Non-reported COVID-19 deaths and other excess deaths are much larger than reported COVID-19 deaths especially in poorer countries (compare the darker and lighter shades of each bar). "

https://www.brookings.edu/blog/future-development/2021/05/27/covid-19-is-a-developing-country-pandemic/

 

You got a problem with the fact that boosters keep people from getting seriously ill and dying? Really?

 

Of course there are fewer flu cases.. Social distancing measures are very effective at keeping people from getting ill with earlier variants of Covid. And the flu variants are less transmissible than covid. So of course there is less flu there. (I haven't seen anything about colds and fevers) There are  agencies responsible for monitoring the flu and they are regularly sent samples taken from people ill with respiratory diseases. These samples are tested. So, no, flu cases aren't being misattributed to covid.

 

 

2 hours ago, placeholder said:

False

How do China’s COVID vaccines fare against the Delta variant?

https://fortune.com/2021/08/31/china-covid-vaccine-sinovac-sinopharm-delta-variant-effective/

Opinion piece by the Fortune.com ... ?

 

Antibodies from Sinovac's COVID-19 shot fade after about 6 months, booster helps - study

https://www.reuters.com/business/healthcare-pharmaceuticals/antibodies-sinovacs-covid-19-shot-fade-after-about-6-months-booster-helps-study-2021-07-26/

 

Here is the study:

https://www.medrxiv.org/content/10.1101/2021.07.23.21261026v1

 

Quote

Results Overall, 540 participants received a third dose. In the 3 μg group, neutralizing antibody titers induced by the first two doses declined after 6-8 months to below the seropositive cutoff

So if not 3 doses, Sinovac is ineffective after 6-8 months. Better than nothing, but not very effective.

 

2 hours ago, ThLT said:

Opinion piece by the Fortune.com ... ?

 

Antibodies from Sinovac's COVID-19 shot fade after about 6 months, booster helps - study

https://www.reuters.com/business/healthcare-pharmaceuticals/antibodies-sinovacs-covid-19-shot-fade-after-about-6-months-booster-helps-study-2021-07-26/

 

Here is the study:

https://www.medrxiv.org/content/10.1101/2021.07.23.21261026v1

 

So if not 3 doses, Sinovac is ineffective after 6-8 months. Better than nothing, but not very effective.

 

Ineffective against transmission or ineffective against serious illness/death? Keep in mind that antibody levels and T-cell protection are 2 different things.

On 12/20/2021 at 3:27 PM, thaivisareader said:

narrative slowly changing. 

The narrative is changing because the virus is changing. And we're learning as we go. That's true of any complex undertaking.

 

What would be silly would be to not adapt to new information.

On 12/22/2021 at 8:27 AM, mtls2005 said:

What was your vaccination history?

 

FYI, 

 

The main City Hall-managed vaccination centre at the Thai-Japanese Youth Centre will close from Dec 29 to Jan 4 during the New Year holidays, said the Bangkok Metropolitan Administration (BMA)'s Health Department on Sunday.

 

 

Good question.  I understand one cannot have a Pfizer booster until 6 months after the 2nd jab?

17 hours ago, placeholder said:

.

 

Quote

Dec 23 (Reuters) - Three doses of Sinovac's CoronaVac COVID-19 vaccine do not produce adequate levels of antibodies to fight the Omicron variant of the coronavirus, researchers from Hong Kong said in a statement.

https://www.reuters.com/world/china/chinas-sinovac-covid-19-booster-weaker-against-omicron-hong-kong-study-2021-12-23/

 

More like medicine vs vaccines based on how many you need a year.

 

Only hope is weaker and weaker strains till it's like the cold or some

full spectrum vaccine working at a different level to give 5-year protection etc...there was one San Diego lab working on something like that..it counteracts covid in a novel longer-term way. ...citation ? google is your friend.

41 minutes ago, ThLT said:

First off, I made my comment about T-Cell immunity.

"Ineffective against transmission or ineffective against serious illness/death? Keep in mind that antibody levels and T-cell protection are 2 different things."

Nothing in the article you linked to makes any mention of T-cell immunity at all.

Second, clearly Sinovac does make important changes in the ability of the ability to create antibodies. If not, why this result reported in the article you linked to?

"Their analysis revealed Pfizer-BioNTech vaccine was more effective, as a third dose of the shot administered after two doses of the same or China's Sinovac vaccine provided "protective levels" of antibody against Omicron."

 

On 12/22/2021 at 3:59 PM, Virt said:

If omicron becomes dominant worldwide, would a new variant not have to become even more transmissible but also less deadly before it's able to take omicrons place?

Not necessarily. Being more transmissible, yes, but more or less virulent is an open question.

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