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LSD Shows Promise as Future Anxiety Treatment

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In recent small-scale studies, the psychedelic drug LSD is resurfacing as a potential treatment for anxiety and depression — conditions many people struggle with worldwide. 

 

In a mid-stage clinical trial of a pharmaceutical LSD formulation called MM120, researchers administered one of several doses (25, 50, 100, or 200 micrograms) to people diagnosed with Generalized Anxiety Disorder (GAD). Those who received the two highest doses reported dramatic improvements. Around half of participants in the 100 µg and 200 µg groups reached remission three months later — without ongoing therapy or daily medication. 

 

LSD isn’t a newcomer to mental-health research. The drug first gained scientific interest in the 1950s and 1960s for treating depression, trauma, and addiction — but was later stigmatized and outlawed. Now, after decades, research is returning with modern controls and clinical standards.

 

The benefits seen may stem from LSD’s effect on brain chemistry: it interacts with serotonin receptors and may encourage neuroplasticity, potentially helping the brain “reset” emotional patterns. However, the drug is not without risks. LSD can also cause intense hallucinations, altered perception, or — in rare cases — panic or paranoia, especially if used outside controlled settings. 

 

Most experts agree that more research is needed — larger, longer-term studies with careful controls — before LSD can become a mainstream treatment. 

 

 

 

 

Key Takeaways

 

A recent trial found a single dose of LSD (100–200 µg) significantly reduced anxiety symptoms in many GAD patients, with effects lasting at least three months.

 

LSD’s potential therapeutic effect may come from its impact on serotonin pathways and promotion of neuroplasticity, helping rewire emotional responses.

 

Despite promise, LSD carries risks — hallucinations, altered perception, and potential psychological instability — and needs much more rigorous research before use as standard therapy.

 

Adapted From 

 

https://www.nationalgeographic.com/health/article/lsd-psychedelic-drug-mental-health-anxiety?

If it's like sillycybin(Psilocybin) then it is useless if you have taken it before as experiments in PTSD alleviation have shown. That excludes anybody that actually had a life in thr 60's and 70's.

We have a world of possibilities with MDMA, LSD and many other drugs, to improve the lives of everyone.

 

When the use of these drugs gains broad acceptance, this will no doubt precipitate a change in our quality of life greater than any technolical advancement.

 

Unfortunately for now the fearful scaremongers still rule the waves.

52 minutes ago, Cameroni said:

We have a world of possibilities with MDMA, LSD and many other drugs, to improve the lives of everyone.

 

When the use of these drugs gains broad acceptance, this will no doubt precipitate a change in our quality of life greater than any technolical advancement.

 

Unfortunately for now the fearful scaremongers still rule the waves.

 

 

I'd be interested in pharmaceutical grade LSD, correct dosage etc.

 

 

They’ve been experimenting at Imperial College London for years. There’s a good paper by Robin Carhart-Harris, The Entropic Brain. The main mode is the raising of entropy in the brain through the disabling of the Default Mode Network, which is both the ‘Fat Controller’ (Thomas the Tank Engine 😋) and creator of ego. 


It does this by apparently affecting blood flow indirectly in the brain along with stimulating serotonin receptors. And because the DMN is offline, you get all sorts of new connections being made, thousands of them, and are able to smell colours etc along with the rebuilding of rigid connections which could be linked with depression, ruminating, OCD and so on. 

 

Good stuff when used ‘correctly’ and with a therapist or in the right frame of mind, but which I suspect is essentially grouped up with dangerous other class A’s because governments are terrified it will make populations overly intelligent. Kennedy partook and was arguably reason behind him making drastic policy changes like wanting to end the Vietnam War, peace with Russia etc… which ironically lead to him being brutally assassinated, which is another story. 

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