Trials underway to test efficacy of Andrographis Paniculata extract for Covid-19

[webfact]

Trials underway to test efficacy of Andrographis Paniculata extract for Covid-19

By The Nation

 

Dr Marut Jirasetasiri

 

The medicinal plant Andrographis Paniculata could be effective in treating Covid-19, the Department of Thai Traditional and Alternative Medicine said, revealing results of preliminary research.

 

The trial will enter Phase 2 with 60 volunteers this September, the department said.

 

Dr Marut Jirasetasiri, director of the department, said that preliminary trials showed that Andrographis Paniculata could be used to fight the Covid-19 virus, as the plant extract could prevent infection from one cell to another in the human body.

 

Trials involving six Covid-19 patients with mild to moderate symptoms were arranged to test an Andrographis extract with a concentration of three times (180mg/day) and five times, Marut said.

 

The results showed that using a concentration of three times found improvement, especially in coughing. Both the cough volume and symptom severity decreased significantly within three days.

 

After five days, the other symptoms began to improve, and real-time polymerase chain reaction (RT-PCR) tests were found to be negative in two patients. After three weeks, RT-PCR was tested again and found that all six were negative and no infection was found. However, the results of the treatment were not confirmed because this was an early study, Marut said.

 

Phase 2 will start in September with 60 volunteers, in the Banglamung Hospital area, Chonburi province, and Samut Prakarn Hospital. The volunteers will be divided into two groups: one of patients receiving Andrographis at three times concentration and the other group will be given a placebo pill for the same period, Marut said.

 

If the test finds that the group given Andrographis showed improvement in symptoms compared to the other group, it could be concluded that Andrographis Paniculata extract could be used to treat Covid-19, but more research would need to be undertaken, he added.

 

Source: https://www.nationthailand.com/news/30393547

 

-- © Copyright The Nation Thailand 2020-08-26

 

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[CelticBhoy]

 

                                 "pronunciation"

"Trials underway to test efficacy of Andrographis Paniculata" 

                                        ^

[ukrules]

Once I was ill and literally did nothing, I just ignored it and it seemed to go away on it's own, amazing that - it also took about 3 days.

 

 

[DrTuner]

Did they publish the study anywhere? I suppose a link would be too much to ask.

[Misterwhisper]

The OP pic looks like Dr. Marut has happily partaken in another "herb".

Edited August 26, 2020 by Misterwhisper

[CHAZ1]

Highly unlikely and the proposed trial groups are too small to produce any statistically valid result(s)

[bluesofa]

2 hours ago, webfact said:

Both the cough volume and symptom severity decreased significantly within three days

I find I can do the same instantly just by using the remote control.

[4MyEgo]

2 hours ago, webfact said:

Trials involving six Covid-19 patients with mild to moderate symptoms were arranged to test an Andrographis extract with a concentration of three times (180mg/day) and five times, Marut said

Good

2 hours ago, webfact said:

The results showed that using a concentration of three times found improvement, especially in coughing. Both the cough volume and symptom severity decreased significantly within three days.

Better

2 hours ago, webfact said:

After five days, the other symptoms began to improve, and real-time polymerase chain reaction (RT-PCR) tests were found to be negative in two patients. After three weeks, RT-PCR was tested again and found that all six were negative and no infection was found. However, the results of the treatment were not confirmed because this was an early study, Marut said.

Great

2 hours ago, webfact said:

Phase 2 will start in September with 60 volunteers, in the Banglamung Hospital area, Chonburi province, and Samut Prakarn Hospital. The volunteers will be divided into two groups: one of patients receiving Andrographis at three times concentration and the other group will be given a placebo pill for the same period, Marut said.

Excellent, but, um, where are they going to get 60 patients who have Covid-19, I thought Thailand was free of Covid-19......that is unless ????

Edited August 26, 2020 by 4MyEgo

[DrTuner]

1 hour ago, 4MyEgo said:

Excellent, but, um, where are they going to get 60 patients who have Covid-19, I thought Thailand was free of Covid-19......that is unless ????

Well spotted. Banglamung hospital is in Pattaya, I wasn't aware of them having a covid ward. Much less patients.

[YTP]

Although I don't know of dosage and how they are delivering their tests, it is basically this stuff.

Widely available at 7-eleven for 20 baht if I remember correctly.

[Damrongsak]

10 hours ago, ukrules said:

Once I was ill and literally did nothing, I just ignored it and it seemed to go away on it's own, amazing that - it also took about 3 days.

OK, what amulet(s) were you wearing?  Did you feed the monks extra every morning? 

[ourmanflint]

My wife made me take this when I tested positive for Covid, and I have to say I felt better after taking it, not much better, but better, My symptoms weren't that bad anyway

[bradiston]

6 hours ago, ourmanflint said:

My wife made me take this when I tested positive for Covid, and I have to say I felt better after taking it, not much better, but better, My symptoms weren't that bad anyway

Any other details about your infection? When, where, how? Were you just allowed to stay home, being treated by your wife?

[Geoffggi]

17 hours ago, webfact said:

Dr Marut Jirasetasiri, director of the department, said that preliminary trials showed that Andrographis Paniculata could be used to fight the Covid-19 virus, as the plant extract could prevent infection from one cell to another in the human body.

Anything that truly works is good news, I was also reading in other news outlets the following:-

A product found in insect repellent can kill the strain of coronavirus that causes COVID-19, research by Britain's defense laboratory has shown.

It is understood that only insect repellent containing Citriodiol and not containing Deet is regarded as having the potential of any kind of utility against the novel coronavirus.

[Srikcir]

India is ahead of Thailand for a cheap vaccine:

Hindu group hosts cow urine drinking party to ward off coronavirus. 

https:/www.dw.com/en/hindu-group-hosts-cow-urine-drinking-party-to-ward-off-coronavirus/a-52773262

Volunteers?

 

[DLock]

Surprised they haven't done clinical trials with Tiffy - pretty sure that will have some positive effects as well.

 

Growing up, it was Dispirin (?), Gatorade and eggs with soldiers when I was sick...

[PatOngo]

I'm working on some pla la, mixed with pic nam pla and a touch of hot chilli powder, I think it has real potential! For the "Ultra", I'll add Singha beer!

[Bender Rodriguez]

it is widely used when you have FEVER...

 

don't take a p.i.s.s. about something that might HELP (not cure) and where you know nothing about

[khunPer]

19 hours ago, 4MyEgo said:

Excellent, but, um, where are they going to get 60 patients who have Covid-19, I thought Thailand was free of Covid-19......that is unless ????

Returning Thais and foreigners in quarantine could be an excellent option...????????

[Rancid]

Herbs have been used for thousands of years to great effect, would hardly be surprising if some help with the virus. Pharmacological drugs generally are faster acting, however come with the associated side effects, herbs much less so or not at all.

 

Needless to say a certain industry does all it can to mock and belittle herbs, not fond of competition. There again some herb packagers do their industry little favors by making false claims. Do the research.

[ourmanflint]

6 hours ago, bradiston said:

Any other details about your infection? When, where, how? Were you just allowed to stay home, being treated by your wife?

Where was in the UK, when was beginning of August. One night of chills and fever then about 8 days of lethargy, no coughing no loss of taste etc. Had a drive in test, results in 18 hours, started taking the Fa Talai Chon pills day test came back positive.