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Thailand to explore injecting coronavirus vaccines under skin


snoop1130

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5 minutes ago, Caldera said:

If that's such a brilliant idea, I wonder why no other country where vaccines were scarce at the beginning of their vaccination campaigns "explored" the same? Or maybe they did and found reasons not to do it!

 

Thailand, once again trying to reinvent the wheel. The hub of not learning from lessons learned elsewhere.

There has been some research about the efficacy of Moderna( I think) being given subcutaneously. 

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I say let all Thai high ranking officials especially the health minister try this first. If they die we will know its not such a great idea. The next brainstorm idea will be cut all 20 million doses of Pfizer in half with water that way they get 40 million out of it. Try not to laugh, they might try it. 

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23 minutes ago, club said:

I say let all Thai high ranking officials especially the health minister try this first. If they die we will know its not such a great idea. The next brainstorm idea will be cut all 20 million doses of Pfizer in half with water that way they get 40 million out of it. Try not to laugh, they might try it. 

They all got shots of "the good stuff" months ago.

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18 hours ago, snoop1130 said:

Our previous experience shows that intradermal injections uses 25% of a muscular injection, but triggers the same level of immunity," head of the medical science department, Supakit Sirilak told reporters.

No other country on the planet realizes this or has adopted it. Amazing Thailand!

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15 hours ago, tomacht8 said:

Whether the moderna observation also applies to the AZ vaccine is a completely different matter. Deciding to reduce the vaccine doses on the basis of a gut feeling, without basic scientific research, is highly risky. To what extent, due to the vaccine shortage in Thailand, this is a medical or a politically motivated decision, remains questionable.

You know well the answer to your question. Around the world countries more or less are moving to the third jab but Thailand is Thailand. A friend yesterday sent me photos from his village and what was going on and it is quite shocking particularly how the people are suffering and dieing in their homes. 

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21 hours ago, djayz said:

To be honest, I'm surprised they haven't tried that yet. Who knows, but maybe that'll be tomorrow's news? 

tomorrow's medical trials will be saving even more doses by injecting air from an empty syringe 

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8 hours ago, club said:

I say let all Thai high ranking officials especially the health minister try this first. If they die we will know its not such a great idea. The next brainstorm idea will be cut all 20 million doses of Pfizer in half with water that way they get 40 million out of it. Try not to laugh, they might try it. 

maybe the health minister can volunteer to have a syringe full of air injected into his carotid artery.......

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23 hours ago, marcusb said:

I won't pretend to understand vaccines and dosages like a doc but if I'm 100kg and a shot is adequate for me wouldn't half a shot be adequate for a 50kg person?  

Yes or pro rated doses up or down by weight across the board?  Sitting at the casino the other day, the size and obesity of many of the people was stunning. 

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20 minutes ago, gk10012001 said:

Yes or pro rated doses up or down by weight across the board?  Sitting at the casino the other day, the size and obesity of many of the people was stunning. 

Vaccination has nothing to do with body weight. The vaccine is not a drug. The vaccine is injected into the delta muscle, where it triggers an immunization process. That means it is a local application. Over time, the body learns to form appropriate antibodies. In practice, however, it is technically more difficult to penetrate all layers of skin and fatty tissue up to the delta muscle in severely overweight people. Doctors also use longer needles then.

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So, if your choice was 1/4 dose of Moderna or full dose of Sinovac, which would you choose?

 

Something to ponder...  It may not be as stupid as you think.

 

Edit:  Or a 1/4 dose of Moderna this month vs a full dose in Q2 of 2022?  Because those may be the options.

 

Edited by impulse
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11 hours ago, RJRS1301 said:

There has been some research about the efficacy of Moderna( I think) being given subcutaneously. 

Subcutaneous is not the same as intradermal.

 

Subcutaneous injections are administered in the fat layer, underneath the skin. 

 

Intradermal injections are delivered into the dermis, or the skin layer underneath the epidermis (which is the upper skin layer).

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On 8/19/2021 at 7:29 PM, Scrotobike said:

More lunacy from the desperate

Just keep inventing such nonsense with no proper (tested) research

Next will be mixing a vax shot with an amluet

Just got this from MedPark Hospital which is offering Moderna @ 3300baht for two doses. I will get my 2nd dose of Pfizer Sept 3rd. Turns out Pfizers' effective rate dropped from 80% to 42% against Delta after 6 months. So now Moderna is flavor of the month although  it will not arrive until Q1-Q2 2022? I am already scheduled for 2 doses of Moderna in October as boosters but now MedPark is not advising mixing vaccines '' *Currently, studies are being conducted in USA and UK regarding MODERNA as the 3rd and the 2nd shot, and in heterologous and homologous vaccination. The studies could take 1 year, starting from June 2021. Updates will be provided as results emerge, but it is currently not a standardized recommendation to use Moderna as a booster or in a heterologous vaccination. Therefore, MedPark will only have the primary series of the Moderna vaccine available, according to the manufacturer’s standards. '' This is beginning to be one of those deals throwing **** against the wall and see what sticks. Looks like a shot every 6 months for a long. long time. 

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5 hours ago, jazzdog32095 said:

Just got this from MedPark Hospital which is offering Moderna @ 3300baht for two doses. I will get my 2nd dose of Pfizer Sept 3rd. Turns out Pfizers' effective rate dropped from 80% to 42% against Delta after 6 months. So now Moderna is flavor of the month although  it will not arrive until Q1-Q2 2022? I am already scheduled for 2 doses of Moderna in October as boosters but now MedPark is not advising mixing vaccines '' *Currently, studies are being conducted in USA and UK regarding MODERNA as the 3rd and the 2nd shot, and in heterologous and homologous vaccination. The studies could take 1 year, starting from June 2021. Updates will be provided as results emerge, but it is currently not a standardized recommendation to use Moderna as a booster or in a heterologous vaccination. Therefore, MedPark will only have the primary series of the Moderna vaccine available, according to the manufacturer’s standards. '' This is beginning to be one of those deals throwing **** against the wall and see what sticks. Looks like a shot every 6 months for a long. long time. 

I am hoping that one round of vaccines will train my body to kick Covid's ass. 

Hope is the last out of pandora's box.

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On 8/20/2021 at 3:27 AM, Credo said:

The vaccine manufacturers put the product through extensive trials and one of those trials is to find out what dosage is required to produced the desired immune response.  

Not true.

All Covid vaccines were rushed onto the market under the Emergency decree.

Not one of them was subject to a full fledged trial as other vaccines were. These trials take YEARS

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On 8/19/2021 at 11:55 PM, marcusb said:

I won't pretend to understand vaccines and dosages like a doc but if I'm 100kg and a shot is adequate for me wouldn't half a shot be adequate for a 50kg person?  

That would be true for some medicines, like morphine e.g.

The vaccines "teach" your system how to make its own "medicine" via your own immune response, is my understanding.

I expect a reduced dose might cause a slightly longer response period, but probably a matter of a couple days of lower response.

A layman's opinion, based on reading. Like to see Sheryl's take, or any other medico's.

 

 

 

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1 hour ago, canthai55 said:

Not true.

All Covid vaccines were rushed onto the market under the Emergency decree.

Not one of them was subject to a full fledged trial as other vaccines were. These trials take YEARS

Not neccesarily true, or not in this case, anyway. The mRNA vaccines are based on decades of research and developement.

Basically a "plug and play" technology. Whole new ball game vs the older "experimental" system. 

Scientists had already been working on corona viruses.

Here's a link, if permissable, that gives the extensive timeline for these vaccines:

"The long road to mRNA vaccines - CIHR" https://cihr-irsc.gc.ca/e/52424.html

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Re: subcutaneous injection of Corona vaccines, everything I have found says "don't do it." Then they go on to say don't administer a second dose, implying the stuff must be  doing something. I'm also minded of smallpox vaccine which was only sub q.

I guess only time and experimentation on a population will tell.

I am reminded of Army experience ehere they lined us up and bing-bang with a pneumatic gun. Don't know how far those penetrate, but seems more sub q. Certainly don't recall what they dosed us with, that was so long ago.

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26 minutes ago, Ireland32 said:

Chinese are already using water Vax useless 

Real world experience with Sinovac has shown it effective against serious disease and mortality.

Just because it is not AS effective as others does not mean its "useless, water, etc." It can be produced quickly and is available to nations with less access to the "top shelf" brands.

A lot of the negativity I see is based on China bashing, predicated in part on the belief, yet to be 100% proven, that it originated there. Not an apologist for them, but I like to see better reasons than "I don't like "them", therefore everything associated with them is useless."

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