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Dementia prevention & cure?

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There has been a lot of scientific buzz recently about Lithium orotate. This is not the formulation of Lithium given to bipolar patients, and only requires 5 or 10 mg doses.

Mouse studies have shown prevention of dementia or mitigation of symptoms if already demented.

This is great news! Although I wonder how mice are tested for dementia. Forget the car keys?

In any case, I never forget to take it! Hope this interests someone. iHerb.

35 minutes ago, unblocktheplanet said:

There has been a lot of scientific buzz recently about Lithium orotate. This is not the formulation of Lithium given to bipolar patients, and only requires 5 or 10 mg doses.

Mouse studies have shown prevention of dementia or mitigation of symptoms if already demented.

This is great news! Although I wonder how mice are tested for dementia. Forget the car keys?

In any case, I never forget to take it! Hope this interests someone. iHerb.

Also new recently studies about Lithium orotate about depression, bipolar, adhd,

Recent studies and research in 2024–2026 are shifting toward treating low-dose lithium—specifically lithium orotate—as a crucial, underutilized neuroprotective agent and potential micronutrient rather than just a high-dose pharmaceutical, with exciting findings for depression, bipolar disorder, and cognitive health.

https://www.sps.healthcare/post/lithium-orotate-benefits-depression-brain-health

35 minutes ago, unblocktheplanet said:

I wonder how mice are tested for dementia.

Deprive them of food then put them in a maze with a food pellet at the end of one of the alleys. They wander the maze aimlessly each new session while normal mice learn to go directly to the pellet within a session or two. That's one example. Also, mice are not humans.

  • Author
On 2/9/2026 at 2:09 PM, Oliver Holzerfilled said:

Deprive them of food then put them in a maze with a food pellet at the end of one of the alleys. They wander the maze aimlessly each new session while normal mice learn to go directly to the pellet within a session or two. That's one example. Also, mice are not humans.

5555! I did know that but liked the joke! Did they find their car keys?

  • 2 weeks later...

The word ‘prevention” in the title.

Recently, I read that Dramamine (Dimenhydrinate) was suggested as a sleep aid. This is a first generation antihistamine.

I tried 25mg before bed and it helps to get a good night sleep.

Great news as it is difficult to buy OTC drugs that help you sleep.

I’ve since found out that this drug should only be used occasionally as long-term or high-dose use of Dramamine (dimenhydrinate) is linked to an increased risk of dementia, particularly in older adults, due to its strong anticholinergic effects.

No drugs available, so back to ‘cognitive shuffling’

(Cognitive shuffling is a sleep-induction technique designed to stop racing thoughts by distracting the brain with random, neutral, and non-threatening mental images.

By mimicking the natural, illogical thought patterns of falling asleep, it helps shift the mind from an active "worried" state to a calm, restful state.)

This mental exercise probably helps in the battle against dementia as well.

I think mental exercises help you get to sleep but it’s kind of boring, the last thing you would want to do at the end of the day.

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