2 Doses of Sinovac Followed by AstraZeneca/Pfizer Give High Immunity Against Omicron , Says Dr. Yong

[snoop1130]

 

BANGKOK (NNT) - According to Dr. Yong Poovorawan, head of the Center of Excellence in Clinical Virology at the Faculty of Medicine, Chulalongkorn University, said people who received two shots of Sinovac followed by a booster shot of AstraZeneca have seen their immunity increase 100 times, or 200 times if followed by a Pfizer booster shot.

 

He said both booster shots can significantly increase T cells, which is effective against Covid-19 variants such as Omicron. He cited data from researchers in Europe and China, on the medRxiv website, studying the effects of 2 Sinovac shots followed by an mRNA booster shot.

 

Meanwhile, he said Chulalongkorn University will publish its own research on combating Omicron in Thailand next week and the results of the study of 2 doses of Sinovac and/or AstraZeneca followed by a booster shot will be published soon.

 

-- © Copyright NNT 2022-01-17

 

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[Bluespunk]

4 minutes ago, snoop1130 said:

According to Dr. Yong Poovorawan, head of the Center of Excellence in Clinical Virology at the Faculty of Medicine, Chulalongkorn University, said people who received two shots of Sinovac followed by a booster shot of AstraZeneca have seen their immunity increase 100 times, or 200 times if followed by a Pfizer booster shot.

Yeah, right...sure they have...

Edited January 17, 2022 by Bluespunk
Punctuation

[Cake Monster]

Yoda Yong has spoken

[Thaiwrath]

[garyk]

I would imagine eating healthy , exercising and keeping fit would do as much or better.

[Cleareye]

Time to put on my boots, the manure is getting deep.

[ozimoron]

As usual the experts are right and the the low no information bashers produce nothing to support their misinformation.

 

Here is a study which supports what he's saying.

 

Antibody responses were low at 6 months after prior immunisation with two doses of CoronaVac, However, all four vaccines administered as a third dose induced a significant increase in binding and neutralising antibody, which may improve protection against infection.

 

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3989848

 

https://www.astrazeneca.com/media-centre/press-releases/2022/new-vaxzevria-data-further-support-its-use-as-third-dose-booster.html

Edited January 17, 2022 by ozimoron

[Denim]

Doh ....Don't you just wish you had had two Sinovac jabs instead of 2 Pfitzer ????

[EricTh]

Trying to promote Pfizer as usual.

[ozimoron]

1 hour ago, Denim said:

Doh ....Don't you just wish you had had two Sinovac jabs instead of 2 Pfitzer ????

There was a period last year when Sinovac was the only vaccine available in Thailand. It would be fair to say that a few people went to their graves wishing they hadn't waited. Sinovac has proved to be effective against serious illness.

 

https://www.reuters.com/world/asia-pacific/sinovacs-covid-shot-highly-effective-against-serious-illness-malaysia-study-2021-09-24/

Edited January 17, 2022 by ozimoron

[MrJ2U]

13 minutes ago, ozimoron said:

There was a period last year when Sinovac was the only vaccine available in Thailand. It would be fair to say that a few people went to their graves wishing they hadn't waited. Sinovac has proved to be effective against serious illness.

That was strictly Thailands fault.

They still don't have enough vaccines on order to provide boosters to everyone.

 

 

[MrJ2U]

23 minutes ago, ozimoron said:

There was a period last year when Sinovac was the only vaccine available in Thailand. It would be fair to say that a few people went to their graves wishing they hadn't waited. Sinovac has proved to be effective against serious illness.

 

https://www.reuters.com/world/asia-pacific/sinovacs-covid-shot-highly-effective-against-serious-illness-malaysia-study-2021-09-24/

"Moderna vaccines the best — and Sinovac least effective — at stopping covid deaths, Singapore data suggests"

https://www.washingtonpost.com/world/2022/01/11/singapore-coronavirus-vaccine-moderna-sinovac-pfizer/

 

HONG KONG

-- "A  third dose of Sinovac's COVID vaccine does not provide sufficient protection against the omicron variant, new research reveals, contradicting the Chinese vaccine maker's pronouncement that it does."

 

https://asia.nikkei.com/Spotlight/Coronavirus/COVID-vaccines/Sinovac-booster-insufficient-against-omicron-study-shows

 

[nattaya09]

But one shot of Omicron gives better immunity than two shots of Sinovac followed by a booster shot of AstraZeneca

[gearbox]

2 hours ago, ozimoron said:

As usual the experts are right and the the low no information bashers produce nothing to support their misinformation.

 

Here is a study which supports what he's saying.

 

Antibody responses were low at 6 months after prior immunisation with two doses of CoronaVac, However, all four vaccines administered as a third dose induced a significant increase in binding and neutralising antibody, which may improve protection against infection.

 

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3989848

 

https://www.astrazeneca.com/media-centre/press-releases/2022/new-vaxzevria-data-further-support-its-use-as-third-dose-booster.html

Whatever Thailand has done seems to be working OK, it is about time to remove the travel and other restrictions.

[ozimoron]

14 minutes ago, nattaya09 said:

But one shot of Omicron gives better immunity than two shots of Sinovac followed by a booster shot of AstraZeneca

Any evidence to that effect? At the time that Sinovac was the main vaccination used omicron wasn't around and delta was the main worry. Sinovac undoubtedly saved many lives.

Edited January 17, 2022 by ozimoron

[Danderman123]

2 hours ago, nattaya09 said:

But one shot of Omicron gives better immunity than two shots of Sinovac followed by a booster shot of AstraZeneca

Unless you die an agonizing death…

[catturd]

Dr. Yong's comments may be accurate, but the problem is the protection levels afforded by the increased antibodies may be insufficient against omicron as reported recently by a small study in Israel and comments from pfizer & moderna CEO's and BioNTech. An omicron specific solution is in the works with both moderna & pfizer now with production ETA March 2022.

https://www.cnbc.com/2021/12/08/omicron-pfizer-ceo-says-we-may-need-fourth-covid-vaccine-doses-sooner-than-expected.html

https://www.euronews.com/next/2021/12/20/omicron-3-vaccine-doses-are-not-enough-to-stop-the-new-covid-variant-warns-biontech-ceo

The UK-HSA published some results of VE data for pfizer and Moderna boosters: pfizer drops to 40% after 10 weeks. Biggest drop is a negative VE 20 weeks after two dose AstraZeneca series. Moderna booster (2 dose mRNA) performed much better. I know some Thai individuals who have purchased several lots of moderna jabs, perhaps they can be used as boosters in TH. 

Edited January 17, 2022 by catturd

[Soikhaonoiken]

5 hours ago, EricTh said:

Trying to promote Pfizer as usual.

Or Sinovac.... 

 

[Siameaze]

not much peer-reviewed science here. Just s convenient opinion

[hotchilli]

15 hours ago, snoop1130 said:

According to Dr. Yong Poovorawan, head of the Center of Excellence in Clinical Virology at the Faculty of Medicine, Chulalongkorn University, said people who received two shots of Sinovac followed by a booster shot of AstraZeneca have seen their immunity increase 100 times, or 200 times if followed by a Pfizer booster shot.

Should I be worried that I had 2X Astra and a Pfizer booster lined up?

[hotchilli]

8 hours ago, nattaya09 said:

But one shot of Omicron gives better immunity than two shots of Sinovac followed by a booster shot of AstraZeneca

3 shots of a single malt works for me.

[ozimoron]

5 hours ago, catturd said:

Dr. Yong's comments may be accurate, but the problem is the protection levels afforded by the increased antibodies may be insufficient against omicron as reported recently by a small study in Israel and comments from pfizer & moderna CEO's and BioNTech. An omicron specific solution is in the works with both moderna & pfizer now with production ETA March 2022.

https://www.cnbc.com/2021/12/08/omicron-pfizer-ceo-says-we-may-need-fourth-covid-vaccine-doses-sooner-than-expected.html

https://www.euronews.com/next/2021/12/20/omicron-3-vaccine-doses-are-not-enough-to-stop-the-new-covid-variant-warns-biontech-ceo

The UK-HSA published some results of VE data for pfizer and Moderna boosters: pfizer drops to 40% after 10 weeks. Biggest drop is a negative VE 20 weeks after two dose AstraZeneca series. Moderna booster (2 dose mRNA) performed much better. I know some Thai individuals who have purchased several lots of moderna jabs, perhaps they can be used as boosters in TH. 

There is a concerted effort on this board by the anti vaxers to incorrectly conflate protection against infection and transmission with protection against serious illness. The failure to draw this distinction is tantamount to a wilful attempt to do so.

 

From one of the articles you quoted -

"The latest research from South Africa, where Omicron was first reported, suggested that two doses of the Pfizer/BioNTech vaccine offered 70 per cent effectiveness in reducing the risk of hospitalisation."

[Venom]

8 hours ago, nattaya09 said:

But one shot of Omicron gives better immunity than two shots of Sinovac followed by a booster shot of AstraZeneca

Natural immunity doesn't count. 

[bruin]

New Israel study, fourth vaccine does nothing for omicron.

https://www.reuters.com/world/middle-east/israeli-study-shows-4th-shot-covid-19-vaccine-not-able-block-omicron-2022-01-17/

[bruin]

The problem is now The Vaccers, will not look in the mirror and admit they made a mistake. Because they f'd up they want everyone else to have the same fate. 

 

[ozimoron]

6 minutes ago, bruin said:

New Israel study, fourth vaccine does nothing for omicron.

https://www.reuters.com/world/middle-east/israeli-study-shows-4th-shot-covid-19-vaccine-not-able-block-omicron-2022-01-17/

another willfully ignorant attempt to imply that the vaccines "do nothing" by failing to mention that they are effective at preventing serious illness.

[JonnyF]

I had my Pfizer booster 2 weeks ago. Since then I've had flu type symptoms for 2 days followed by a sharp intermittent pulsating pain that moved from the injection site to my shoulder blade and is currently at the middle of my back.

 

Think I'd rather have had Covid.

[WorriedNoodle]

What happened to the 4th jab plan then for people who had already had two Sino's and a AZ Booster?

 

I thought they were starting on the 4th jab for the vulnerable - but no where is this on offer?

[goldenbrwn1]

Watching Thai news this morning, it looks like Pfizer is the new bogeyman vaccine…Since the old lady that sadly passed it looks like Sinovac is the new golden boy and the government was right all along to stick with the CCP vaccine . Plenty of old lady’s (eating) with thumbs up because they didn’t drop dead from Sinovac on screen . ???? 

[Gottfrid]

It can also just be that the man might have Chinese ancestors.