Niacin 100mg

[Celsius]

I bought me a Niacin on Lazada (21st Century brand - cheap).

 

I took a pill and was fine. My wifey took one and started feeling how, itchy, numb and red all over.

 

After reading a bit this seems to be a very common and harmless side effect.

 

But I also read that recommended daily dosage should be under 35mg. Is 100mg safe to take daily.

 

I googled, but want some members real world experiences.

 

 

[retarius]

It is very common with niacin. Try to get an extended relief for your wife.

[Celsius]

4 minutes ago, retarius said:

It is very common with niacin. Try to get an extended relief for your wife.

 

Kinda hard to find in Thailand. Do you have a link?

 

Also, do you think 100mg a day is safe? Do you take it yourself?

[KhunLA]

9 minutes ago, Celsius said:

But I also read that recommended daily dosage should be under 35mg. Is 100mg safe to take daily.

 

I googled, but want some members real world experiences.

 

 

No a problem if you can tolerate it, as niacin is a water soluble vitamin, not stored in fat, and you / she will P out any unabsorbed excess.

 

Next time, you might want to research a vitamin / mineral (and drugs) before experimenting on your body.

[Celsius]

1 minute ago, KhunLA said:

Next time, you might want to research a vitamin / mineral (and drugs) before experimenting on your body.

 

Yes, that would be a good idea. I did not have any reaction at all, but wife did. Was ready to go to the hospital if I didn't start googling.

 

 

[connda]

I don't know why you're taking high dosages of niacin.  50 mg is enough to make a person uncomfortably flushed.  If you want B vitamins, just buy a good multi-B vitamin.  You need less than 20 mg a day.

[Celsius]

2 minutes ago, connda said:

I don't know why you're taking high dosages of niacin.  50 mg is enough to make a person uncomfortably flushed.  If you want B vitamins, just buy a good multi-B vitamin.  You need less than 20 mg a day.

 

Honestly, I already thought I bought a low dosage. Others are selling 500mg.  I can't see anything lower in Thailand. Maybe I will just cut a pill in half for wifey.

Edited yesterday at 03:37 AM by Celsius

[JBChiangRai]

When excess niacin is broken down into 4PY, this breakdown product activates inflammatory pathways that are known to promote plaque formation in arteries. This may increase the risk of major cardiac events.
 

it can also cause liver problems and is not recommended for anyone diabetic or pre-diabetic.

 

I have it in powder form from China and I stopped taking it.

[KhunLA]

11 minutes ago, Celsius said:

 

Yes, that would be a good idea. I did not have any reaction at all, but wife did. Was ready to go to the hospital if I didn't start googling.

 

 

Unless you have a known deficiency, you both may want to stop taking niacin and all supplements.  Suggest you get a blood test to evaluate you nutritional levels of vitamin/minerals.

 

A negative aspect of niacin and why some suggest not taking .

 

edit:  @JBChiangRai you beat me to it, I type so slow 🙄

Edited yesterday at 03:42 AM by KhunLA

[JBChiangRai]

3 minutes ago, KhunLA said:

edit:  @JBChiangRai you beat me to it, I type so slow 🙄

probably because if I’m using my phone, I dictate my posts.

 

That is why I have to manually correct them so often 555

[scubascuba3]

Better to avoid vitamins and improve diet where possible

[Foxx]

Next time, rather than getting niacin (nicotinic acid) get nicotinamide which does not cause flushing.  Same vitamin, different formulation.

[Celsius]

This thing everyone is posting about plaque I googled yesterday.

 

It seems to be a very minor issue and only if taken in excess. Every single thing has side effects, even a good diet.

[KhunLA]

1 hour ago, scubascuba3 said:

Better to avoid vitamins and improve diet where possible

I've recently stopped taking a multivitamin (MV), since eating a more 'whole foods' diet.   Should be getting a more balanced nutrient intake, especially since the MV was providing 100-200+ % of RDA of a few of them.

 

Even if the RDA is a bit low, that's still pushing it, if eating healthier foods.  Still take a Vit C & Magnesium, as notice the good effect of the Mg.

 

End of the year, when I get my blood work done, I'm going to add the nutritional test, to see if lacking or needing anything.

Edited yesterday at 05:25 AM by KhunLA

[connda]

5 hours ago, Celsius said:

 

Honestly, I already thought I bought a low dosage. Others are selling 500mg.  I can't see anything lower in Thailand. Maybe I will just cut a pill in half for wifey.

Just buy a mult-B vitamin.  I use Nat B which you can find in any pharmacy. It contains 50 mg of nicotinamide which is a form of vitamin B₃ which doesn't cause flushing along with 50 mg of a bunch of other B vitamins.

[mstevens]

It's called the "Niacin flush" and it's a well-known result of supplementing with Niacin / B3.

 

Do be a little careful when supplementing with single B vitamins in high doses. The reason for this is that if you are deficient in one B vitamin, when you fix that deficiency then various enzymatic processes will take place and they need co-factors which are often other B vitamins. For example, in many enzymatic processes, B1 also needs a certain amount of B6. It can help to take a B complex - which is all of the B supplements in one pill.

[newbee2022]

20 hours ago, Celsius said:

I bought me a Niacin on Lazada (21st Century brand - cheap).

 

I took a pill and was fine. My wifey took one and started feeling how, itchy, numb and red all over.

 

After reading a bit this seems to be a very common and harmless side effect.

 

But I also read that recommended daily dosage should be under 35mg. Is 100mg safe to take daily.

 

I googled, but want some members real world experiences.

 

 

Actually there is no reason to take supplements in Thailand. You get all what you need in various fruits and vegetables.

And in old age you need only 15 mg Niacin equivalents, which you'll get definitely with your daily food. You might add a handful nuts.

[john donson]

if your wife gets red... she must be high in histamines

 

when a mozzie bite her, does she get giant reactions to the bite?

 

for lowering cholesterol , 2000 mg per day is advised

 

best to take in 500 mg pills... it will lessen over time, the harmless burn

[john donson]

21 hours ago, scubascuba3 said:

Better to avoid vitamins and improve diet where possible

 

yes, better take statins for sure, right, which deplete coq10 and you might get your heart attack sooner, but at least, on paper, your ldl will be low...lol...   and let's not forget (irony) alzheimer's in people with extreme low LDL

[DFPhuket]

My dermatologist has recommended Nicotinamide (similar but different) which does not cause flushing. I mistakenly bought Niacin once, and I had the same flushing reaction that lasted for a few hours. 

 

A 2015 New England Journal of Medicine article found that Nicotinamide (vitamin B3) has been shown to have protective effects against damage caused by UV radiation and to reduce the rate of new premalignant actinic keratoses. (Source) Hence, the recommendation. 

 

 

[Globalres]

On 10/1/2024 at 10:36 AM, Celsius said:

 

Honestly, I already thought I bought a low dosage. Others are selling 500mg.  I can't see anything lower in Thailand. Maybe I will just cut a pill in half for wifey.

I take nicotinamide mononucleotide, nicotinamide being a derivative of vit B3.  It assists in the creation of NAD+ which “communicates” and helps to create ATP (the body’s energy currency).  NAD+ has a “communication line” with ATP and directs it to the areas of the body most in need of ATP in cell restoration.  It is considered to be a “longevity” assistant, by helping to repair problems at the cell level. I personally buy from iHerb which is more guaranteed to have “clean” products.

[JAS21]

An option is B1 B6 B12 ampoules. Injected direct into your bum.

 

My wife and I have used this for years. It’s a very good idea to get your doctor to show you the safe area to inject and how to prepare the injection. You don’t want to be injecting any air, or hit a nerve and of course clean the area first with alcohol.

[WDSmart]

I've never taken Niacin, but I take a vitamin B supplement daily, along with many other supplements. I've never had any problems.

[Shmo]

On 10/1/2024 at 10:22 AM, retarius said:

It is very common with niacin. Try to get an extended relief for your wife.

Slow release non flushing niacin is what you need 

[retarius]

On 10/1/2024 at 12:27 PM, Celsius said:

 

Kinda hard to find in Thailand. Do you have a link?

 

Also, do you think 100mg a day is safe? Do you take it yourself?

I worked in the industry with a competitor to niacin. The major brand in the US is Niaspan. Initial dose is 500mg daily and after a month to increase to 1000mg per day. The maintenance dose is 3000 mg. So that said, 100mg doesn't seem unreasonable, indeed seems too low to do anything for your cholesterol.....but, like allergies, my sense is that if you are sensitive to flushing, you will flush at pretty much any dose of immediate release but may not flush with the extended release. 

I don't take niacin now, but I took it in the past. I just used the immediate release stuff from the local pharmacy....very cheap. I am not a flusher, so was ok with that. Niacin is actually a unique dyslipidemic agent, pretty much moving all the segments like LDL, HDL and ApoA1 and 2 in the right directions, but its action on LDL pales next to statins. Its main medical US is in men who have had prior MIs and in which it works exceptionally well at 3000mg per day. 

If you called the pharmacy at Bumrugrad, they will give you a price....then you will know it is available. Alternatively you can go to your local pharmacy and see if they have a MIMS book for Thailand, and if you look it up in MIMS you know it is available somewhere.....but if you know a pharmacist well enough I'm sure they will order it for you. Sheryl will know the pharmacy chain where to get things best

[LosLobo]

On 10/1/2024 at 10:16 AM, Celsius said:

I bought me a Niacin on Lazada (21st Century brand - cheap).

 

I took a pill and was fine. My wifey took one and started feeling how, itchy, numb and red all over.

 

After reading a bit this seems to be a very common and harmless side effect.

 

But I also read that recommended daily dosage should be under 35mg. Is 100mg safe to take daily.

 

I googled, but want some members real world experiences.

I've been using low-salt Vegemite, an Australian favorite, for my niacin needs for some time due to issues with vitamin B3 supplements. However, I've recently encountered supply problems, so I'm considering brewer's yeast tablets as my next option.

Here is an AI analysis some might find interesting:

Comparison of Brewer’s Yeast Tablets and B3 Supplements

Brewer’s Yeast Tablets
Benefits:

• Nutritional Profile: Rich in B vitamins (B1, B2, B3, B5, B6, B12), protein (about 40%), and minerals like chromium and selenium.
• Digestive Health: Acts as a probiotic, enhancing gut flora and nutrient absorption.
• Blood Sugar Regulation: Chromium can improve insulin sensitivity.
• Immune Support: Contains antioxidants that may boost immunity.
• Energy Boost: High B vitamin content supports energy production.

Issues:

• Potential digestive discomfort (bloating, gas).
• Allergic reactions in those with yeast allergies.
• Possible interactions with diabetes medications.
• Limited scientific research compared to isolated supplements.

B3 (Niacin or Niacinamide) Supplements
Benefits:

• Skin Health: Improves skin elasticity, treats acne, and reduces hyperpigmentation.
• Cholesterol Management: Raises HDL ("good") cholesterol and lowers triglycerides.
• Energy Production: Crucial for converting food into energy.
• Anti-Inflammatory Effects: Reduces inflammation and oxidative stress.
• Nervous System Support: Important for brain function and mental health.

Issues:

• Niacin may cause flushing (redness, itching) at high doses.
• Gastrointestinal distress (nausea, vomiting).
• Risk of liver toxicity at high doses.
• Potential interactions with cholesterol medications and blood thinners.

Summary

Brewer’s yeast offers a broader nutritional array, supporting overall health and digestion, while B3 supplements target skin health and cholesterol management. The choice between them should align with individual health needs, and consulting a healthcare professional is advisable for personalized guidance.