I have made road trips in many countries (Europe, US, S-Korea, Japan) and from that I know that if you like, or at least don't mind, a lot of driving you can make a round trip through Thailand. Up north to Mae Hong Son, down along the Myanmar border, down to Krabi area and Phuket, then back north into Isan and back to Chiang Mai. Doable.

Depends where you live.  If in CM area, since you'll be there afterward, then head south till bored, then head back and do what ever interest you in the north, if time allows.   North will always be there, so take advantage of self driving away from the 'local' area.  Can do that anytime on short local exploring.

 

Kind of personal, along with depending how much of the north or south, you've already been to, and 'when'.  If during smog season, then the north will be a new experience without the smog, and actually enjoyable, outside the metro areas.

 

If you only visit metro areas, then you won't notice the difference.

 

I'm a fan of the south myself, as the limestone karsts, are different than most landscapes that I've seen and enjoyed.  Along with the southern version of some foods.  Added plus of both, beaches and hills to view.

17 hours ago, FriscoKid said:

You would. Traveling long distances overland within Thailand for weeks on-end is only recommended for low-class, budget-stricken twonkers. 

Describes me perfectly.

17 hours ago, FriscoKid said:

You would. Traveling long distances overland within Thailand for weeks on-end is only recommended for low-class, budget-stricken twonkers. 

... low class, budget stricken ... excuse me  

 

Long distance ... Thailand ... you are joking right.  When you can drive top to bottom or east to west in a day, nothing is long distance.

 

... Thailand covers about 513,000 square kilometres, stretching approximately 1,715 kilometres from north to south and 915 kilometres at its widest point from east to west ... 

 

@ 80 kph average, that's only 1 day, 24 hrs.

 

Didn't bother reading much further, after replying to the 'title', as in true AN fashion, see it turned into the usual sh!tshow.

Why can’t you just answer this yourself?
 

We have all enjoyed your travels of visiting every place in Issan on a motorcycle. I recall you doing the south too.

 

Tou describe these places all in the same way: I went to the night market. They had a good band. Me and my girlfriend of the day ate meat on a stick. It was good.

 

Why even go anywhere if it’s all the same to you?

 

What was the best meat on a stick you ate out of your many meat on a stick adventures?