Virology expert says cross-vaccination in booster dose produces very high immunity against Covid

[snoop1130]

 

BANGKOK (NNT) - With the two-dose regimen for vaccination against COVID-19 deemed as no longer offering an adequate level of protection against the disease, Thai health authorities are ramping up the administering of the booster or third dose. Meanwhile, Thailand’s top virologist has indicated that cross-vaccination produces very high immunity in inoculated individuals.

 

Dr. Yong Poovorawan, a virology expert at Chulalongkorn University’s Faculty of Medicine, cited a study jointly conducted by Oxford University and agencies in Brazil, published in The Lancet medical journal. He said the study found that full inoculation of an individual with an inactivated vaccine followed by a booster dose of either a viral vector or mRNA vaccine greatly heightens the individual’s immunity against Covid. Dr. Yong added that similar results have been obtained in studies in Sweden and Indonesia.

 

The head of Chulalongkorn University’s Center of Excellence in Clinical Virology also cited a study in Chile that sought to determine the efficacy of boosters doses which are administered to people inoculated with 2 doses of the CoronaVac (Sinovac) inactivated vaccine. In the study, the third doses comprised the CoronaVac, the AstraZeneca virus vector vaccine, and the Pfizer mRNA vaccine. The boosters were 78.8%, 93.2%, and 96.5% effective in preventing symptoms, respectively. They were 86.7%, 98.1%, and 96.8% effective in preventing deaths, respectively. Dr. Yong said this study was presented as a ’pre-print’ article in The Lancet.

 

The virology expert said the studies support the findings by his clinical virology center, which yielded similar results and are published on the MDPI platform. He added that the center will be submitting another study, this time relating to immunity against the Omicron coronavirus variant, this week. The study compares the efficacy of booster dose delivery at 3 months and 6 months after the date of administering the second shot. Dr. Yong said delivery 6 months after the second shot produced greater immunity, but comes with the downside of leaving a wider time window for the individuals to become infected.

 

Dr. Yong asserted that international-level studies have found that cross-vaccination produces very high immunity and is certainly be able to reduce the death rate from COVID-19.

 

-- © Copyright NNT 2022-01-26

 

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[tandor]

Sorry Doctor, I really hope you didn't actually say these words! There is no 'immunity' against Sars-Covi-2 and Covid-19.

A person can catch this virus regardless of being vaccinated.

This is bad reporting.  I hope you retract your statement.  ????

[chilli42]

Well if this is the kind of advice the government is acting on it’s no wonder that the Covid policies are so pathetic.

[hotchilli]

14 hours ago, snoop1130 said:

Thailand’s top virologist has indicated that cross-vaccination produces very high immunity in inoculated individuals.

Full of wisdom this fella.

[law ling]

1. Always good to hear Yong's pearls of wisdom.

 

2. And, good to hear that the vaccines are proving to be somewhat better than just an injection of a saline solution. (I presume all these studies had control groups?)

 

3. These kinds of reports cited here just collect and report data - which could just as easily be done by a junior lab assistant? ... and leave our "top virologist" free to roll his sleves up and do new and real research into new treatments.

[placeholder]

1 hour ago, tandor said:

Sorry Doctor, I really hope you didn't actually say these words! There is no 'immunity' against Sars-Covi-2 and Covid-19.

A person can catch this virus regardless of being vaccinated.

This is bad reporting.  I hope you retract your statement.  ????

Wrong. There is no absolute immunity to covid-19 on a population wide basis. But there is immunity. This is why immunity is assigned a percentage comparing those vaccinated to the unvaccinated.

[law ling]

2 minutes ago, placeholder said:

Wrong. There is no absolute immunity to covid-19 on a population wide basis. But there is immunity. This is why immunity is assigned a percentage comparing those vaccinated to the unvaccinated.

1. Indeed, it would be unethical, I suppose, to also compare results with a group that received only a placebo (e.g. a saline solution, or a vaccine spoiled by incorrect storage).

 

2. Nevertheless, I always find it odd - and it causes me to wonder - that they say some vaccine is say "98% effective" in preventing something, when it appears to be the case that say 98% of people either don't contract the disease, or get only a mild or asymptomatic form.

 

(Disclaimer: I don't read research reports. In the best traditions of being a ThaiVisa member, I just hold unsupported opinions.)

[placeholder]

1 minute ago, law ling said:

1. Indeed, it would be unethical, I suppose, to also compare results with a group that received only a placebo (e.g. a saline solution, or a vaccine spoiled by incorrect storage).

 

2. Nevertheless, I always find it odd - and it causes me to wonder - that they say some vaccine is say "98% effective" in preventing something, when it appears to be the case that say 98% of people either don't contract the disease, or get only a mild or asymptomatic form.

 

(Disclaimer: I don't read research reports. In the best traditions of being a ThaiVisa member, I just hold unsupported opinions.)

If a vaccine were judged to be 98% effective that would mean that for every 100 cases of unvaccinated people who contracted the targeted illness, only 2 vaccinated people would contract the illness. It does not mean that 98% if the vaccinated group would not contract the illness.

Effective, in the context of epidemiology, also can mean different things. For example, a vaccine may be on 40% effective in reducing symptomatic infection, but 90% effective in reducing mortality.

[Henryford]

It's like saying that seat belts give you immunity to injury in a car crash. They might lessen the effects but you are not immune.

[paul1804]

There is known proof that the vaccination offers partial protection and in most cases will reduce the symptoms of Covid 19. However subsequent booster shots become far less effective and reduce by about half in effectiveness from each administered booster. According to the CDC in the USA most covid vaccines only last for around 20 weeks and offer less protection as they age. If you get covid 19 and you are unvaccinated after you have recovered your natural immunity will give you very slightly better immunity than the MRNA vaccine itself, how long for they did not say but most likely longer than the vaccination which will not please the vaccine manufacturers and most likely why they didn't highlight this. 

[placeholder]

19 minutes ago, paul1804 said:

There is known proof that the vaccination offers partial protection and in most cases will reduce the symptoms of Covid 19. However subsequent booster shots become far less effective and reduce by about half in effectiveness from each administered booster. According to the CDC in the USA most covid vaccines only last for around 20 weeks and offer less protection as they age. If you get covid 19 and you are unvaccinated after you have recovered your natural immunity will give you very slightly better immunity than the MRNA vaccine itself, how long for they did not say but most likely longer than the vaccination which will not please the vaccine manufacturers and most likely why they didn't highlight this. 

Your allegation about diminishing effectiveness of repeated vaccinations is apparently false:

Israeli study reports fivefold jump in antibodies with 4th Pfizer vaccine shot

https://www.washingtonpost.com/world/2022/01/04/israel-fourth-shot-booster/

 

As for natural immunity being superior to immunity acquired through vaccination, the situation is not nearly as clear cut as you make it out to be:

https://www.dw.com/en/omicron-is-natural-immunity-better-than-a-vaccine/a-60425426

https://www.hopkinsmedicine.org/health/conditions-and-diseases/coronavirus/covid-natural-immunity-what-you-need-to-know

[nausea]

It's a complex, evolving, subject, and the powers that be seem to be continually behind the curve.  Personally, I find Dr. John Campbell's stuff to be objective and based on the data, even though, horror of horror's, he's a YouTube presenter. A recent interview with Professor Robert Clancy was particularly interesting. 

[overherebc]

4 hours ago, chilli42 said:

Well if this is the kind of advice the government is acting on it’s no wonder that the Covid policies are so pathetic.

He did mention that the info' was in The Lancet, and based on studies by Oxford Uni and studies in Brazil.

[thailand49]

Reporting commenting on other studies now he should get his own government off their butt and get vaccines like Pfizer,  Moderna,  for everyone!  and it should all be free!  

[ChrisY1]

An attempt to appease those that were given the Chinese junk.....not sure if I'de go and see him for a consultation!

 

[Caldera]

But for how long will the booster offer protection? It might be gone just as quickly as whatever we had from the first two jabs!

[chilli42]

3 hours ago, overherebc said:

He did mention that the info' was in The Lancet, and based on studies by Oxford Uni and studies in Brazil.

Undeniably reliable then.

[overherebc]

36 minutes ago, chilli42 said:

Undeniably reliable then.

Asking or stating?

[tandor]

6 hours ago, placeholder said:

Wrong. There is no absolute immunity to covid-19 on a population wide basis. But there is immunity. This is why immunity is assigned a percentage comparing those vaccinated to the unvaccinated.

..don't agree at all.

My reference is Professor V. Racianello podcast series This Week in Virology.

[DBath]

23 hours ago, snoop1130 said:

Dr. Yong said this study was presented as a ’pre-print’ article in The Lancet.

“Dr. Yong said this study was presented as a ’pre-print’ article in The Lancet.”

This wreaks highly as “not ready for primetime” and misleading, IMO. Sounds like a familiar and common theme. Why do we continue to compound what has already been rushed? I’m sure some who are among the dwindling population of rabid pro-vaxxers will be on here giving their seething opinions. Maybe I’m wrong, but it seems there is an ever-growing groundswell of skepticism around ‘the science’ and various governments who want to force this on everyone, including children. And there are many reasons why people don’t trust big pharma, big government and science. Just my opinion and I’m pretty sure I’m not alone.

[Westie1]

6 hours ago, placeholder said:

Your allegation about diminishing effectiveness of repeated vaccinations is apparently false:

Israeli study reports fivefold jump in antibodies with 4th Pfizer vaccine shot

https://www.washingtonpost.com/world/2022/01/04/israel-fourth-shot-booster/

 

As for natural immunity being superior to immunity acquired through vaccination, the situation is not nearly as clear cut as you make it out to be:

https://www.dw.com/en/omicron-is-natural-immunity-better-than-a-vaccine/a-60425426

https://www.hopkinsmedicine.org/health/conditions-and-diseases/coronavirus/covid-natural-immunity-what-you-need-to-know

Fourth time a charm?

[pedro01]

No more of these vaccines for me. I've had the 2 they told me to get. 

 

For me to have another one - I need some evidence that it is going to be beneficial to me. 

[metisdead]

A post with a video from an unapproved social media source has been removed. 

 

18) Social Media content is acceptable in most social forums. However, in factual areas such as news, current affairs and health topics, it cannot be used unless it is from a credible news media source or government agency, and must include a weblink to the original source.

[Bluespunk]

On 1/26/2022 at 1:07 PM, snoop1130 said:

Meanwhile, Thailand’s top virologist has indicated that cross-vaccination produces very high immunity in inoculated individuals.

Sweet.

I’ve had Astra-Zenica, Pfizer and a Moderna booster. 
 

To paraphrase Gilbert and Sullivan  “I am the very model of a modern inoculated individual”

Edited January 27, 2022 by Bluespunk

[KhunBENQ]

7 hours ago, thailand49 said:

Reporting commenting on other studies now he should get his own government off their butt and get vaccines like Pfizer,  Moderna,  for everyone!  and it should all be free!  

Pfizer is offered for free since quite a while. Even here in the sticks. Moderna? Not that I know. I paid for it at a private hospital. Got it as 3rd shot on December 17.

I had an "IgG" antibody test done on Jan 3 and had a tremendous value of 8000.

 

It's "fascinating" to read how the forum Covid experts axe a Thai doctor citing studies and proven results from reputable sources.

What else do you think a German health minister (calling himself a medical expert) does all day?

Unfortunately the outcome is panic and confusion.

Edited January 27, 2022 by KhunBENQ

[ravip]

At the rate these vaccines are 'marketed' world-wide, I wonder if anyone really knows about them!

[EricTh]

Not this Dr Yong again.... Doesn't Thailand have other experts besides him who can challenge what he said?

Edited January 27, 2022 by EricTh

[Scott]

Trolling graphic removed.

 

[sapson]

20 minutes ago, KhunBENQ said:

had an "IgG" antibody test done on Jan 3 and had a tremendous value of 8000

Did you get the antibody test done at a private hospital in KK or at one of the labs, what was the cost?

 

 

Thanks

[Scott]

It seems rather clear at this point that the level of immunity is going to wane whether it is from an actual infection or a vaccine.  The longevity varies, but not by a lot.  That is how the immune system, it produces antibodies in the face of an infection and when the infection is over the antibodies disappear.  They are no longer needed.   The various memory cells, however, are armed with the ability to jump into action should a new infection come along, but that part of the immune system takes time to react.   

 

If you are exposed when antibodies are high, there is a good chance you will not get sick and may not even test positive.  If the antibodies have largely waned, then the virus gets a chance to get 'seeded' and you will experience an infection, at least until the immune system has time to start producing antibodies again.  Since the body knows exactly what it is fighting, the response is quicker and efficient.   Thus we see people who are vaccinated still getting an infection, but tending not to get seriously ill.   

 

So, if you want a high level of immunity and antibodies it will very likely require repeated boosters.   With many viral infections, they occur seasonally (or on some identifiable timetable), so we boost for them as the risk rises.  With Covid, it's everywhere all the time and that presents unusual challenges.