By Subhabhong Rarueysong

   

BANGKOK (NNT) - Thailand’s Government Pharmaceutical Organization (GPO) has reported that the results of the first phase of human trials of a COVID-19 vaccine candidate, being developed by the GPO and Mahidol University’s faculty of tropical medicine, are promising and the official results will be released next month.

 

GPO Director Dr. Vitoon Danwiboon said the first phase trial of HXP-GPOVac, which uses inactivated virus technology, has produced positive results in terms of safety and triggering an immune response. Samples have been sent for analyses in labs, run by the Department of Medical Sciences and National Science and Technology Development Agency, as well as to labs overseas.

 

He said two out of five formulae will be selected for the next phase, with a group of 250 volunteers, and the one showing most promise will be used in the trial’s third phase.

 

According to Dr. Vitoon, HXP-GPOVac was developed using a different technology, aimed at triggering immunity against virus mutations. It is also effective against the Alpha variant and tests are underway to determine its effectiveness against the Beta and Delta variants.

 

-- © Copyright NNT 2021-06-28

 

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49 minutes ago, webfact said:

the official results will be released next month.

You could release the results now.

Prediction: There were no side effects or adverse conditions shown by any of the volunteers, and Thailand has the best vaccine in the world. 

46 minutes ago, webfact said:

It is also effective against the Alpha variant and tests are underway to determine its effectiveness against the Beta and Delta variants.

Considering the Delta s about to decimate Thailand's health system , if its not effective they may as well abandon what they have and start again

23 minutes ago, Thaiwrath said:

You could release the results now.

Prediction: There were no side effects or adverse conditions shown by any of the volunteers, and Thailand has the best vaccine in the world. 

Why would they release the results now? You wait until the phase is finished and then do the analysis. 

7 minutes ago, RichardColeman said:

Considering the Delta s about to decimate Thailand's health system , if its not effective they may as well abandon what they have and start again

The Who (as opposed to The WHO) standard is 50% so we'll see what is "effective."

I fell deep symphony to the test human subjects who will take part in testing this concoction...

Why reinvent the wheel.

Import the bloody vaccine. Beg borrow or steal.

 

19 minutes ago, DrJack54 said:

Why reinvent the wheel.

Import the bloody vaccine. Beg borrow or steal.

 

Can't make money selling it to neighboring countries that way!

2 hours ago, ezzra said:

I fell deep symphony to the test human subjects who will take part in testing this concoction...

...you think all this orchestrated?

'Trials of Thai COVID-19 Vaccine Are Promising' much, but delivering little - a bit like the rest of the country really.

2 hours ago, RichardColeman said:

Considering the Delta s about to decimate Thailand's health system , if its not effective they may as well abandon what they have and start again

 

The delta variant is about to decimate Thailand's health system?? Really?  Any sources for this rather outlandish claim?

15 minutes ago, eeworldwide said:

 

The delta variant is about to decimate Thailand's health system?? Really?  Any sources for this rather outlandish claim?

No he won't have any sources.

However I don't regard the claim as outlandish in the slightest.

 

36 minutes ago, eeworldwide said:

 

The delta variant is about to decimate Thailand's health system?? Really?  Any sources for this rather outlandish claim?

Well, it may be a little overstated but Bangkok's hospitals are severely stressed. Thaivisa.com prohibits links to Bangkok post but if you do a search for "covid beds running out bangkok post" you'll find that all critical care beds in state-run hospitals were fully occupied as of 5 days ago. Except for 20 beds reserved for emergencies. And the trend lines don't look good.

2 hours ago, DrJack54 said:

Why reinvent the wheel.

Import the bloody vaccine. Beg borrow or steal.

 

Why not just buy more AZ from SB?

And if all its undistributed inventory is llegedly destined for sale (16 million doses) to the Philippines, deny export as a matter of national security and distribute to Thai residents first.

5 hours ago, RichardColeman said:

Considering the Delta s about to decimate Thailand's health system , if its not effective they may as well abandon what they have and start again

On top of that Al Jazeera has reported that there is now a Delta+ variant.  

I thought I remembered an earlier article saying it was mRNA based.  But now inactivated virus based, which does make more sense.  

Now the monkey is out of the sleeve , they where waiting for this all along so they could use their own imstead of spending billions of baht ordering( now this money can be pocketed as a large portion already has been and they where a bit short but that certenly will not show now)

I wrote about this months ago already , the NDV-HXP-S vaccine looked very promising and being produced in Thailand , Vietnam . It is being cultivated inside chicken eggs and very cheap to make and can be made by millions . Took a while for them to finaly tell the masses about it . 

6 hours ago, RichardColeman said:

Considering the Delta s about to decimate Thailand's health system , if its not effective they may as well abandon what they have and start again

This old technology seems inappropriate for a fast mutating virus. The Chinese vaccines offer insight into this issue.

1 hour ago, Srikcir said:

Why not just buy more AZ from SB?

And if all its undistributed inventory is llegedly destined for sale (16 million doses) to the Philippines, deny export as a matter of national security and distribute to Thai residents first.

Maybe you will never travel again, Bud, but everybody needs jabs no matter where they live. I believe this was Siam BS' contractual obligations to other countries.

In the race for a vaccine, Pfizer and Moderna conducted the first, second, and third trials at the same time, not consecutively. That is why they were so fast to the market. 

4 hours ago, eeworldwide said:

 

The delta variant is about to decimate Thailand's health system?? Really?  Any sources for this rather outlandish claim?

Based on the fact that their hospital system and ICU is overflowing with other variants and collapsing (stay at home and wait for a bed orders), and the Delta hitting them which is much more transmissible, I think it a safe bet if they cannot handle a weaker one , a stronger one will do far more damage to their health care system.

 

Trust me, I'd be more than happy to be proved wrong

2 hours ago, rwill said:

I thought I remembered an earlier article saying it was mRNA based.  But now inactivated virus based, which does make more sense.  

 

Chulalongkorn is developing the mRNA vaccine that just started Phase I trials. Prof Drew Weissman at University of Pennsylvania, noted pioneer of mRNA technology, has been working with them.

 

https://www.chula.ac.th/en/clipping/47302/

 

If this is in fact a mRNA vaccine, which only two companies know how to produce (that took more than a decade of research), and it can be stored at cool and room temperature, this should be a world news headline!

2 hours ago, rwill said:

I thought I remembered an earlier article saying it was mRNA based.  But now inactivated virus based, which does make more sense.  

There were a number of different Thai vaccines being developed. The one from Chulalongkorn University is mRNA-based, this one (from Mahidol University) isn't.

19 minutes ago, Redline said:

If this is in fact a mRNA vaccine, which only two companies know how to produce (that took more than a decade of research), and it can be stored at cool and room temperature, this should be a world news headline!

It's not, it's an inactivated virus vaccine.

I live in Chiang Mai and I don’t know any foreigners have been vaccinated yet TIT

8 hours ago, Thaiwrath said:

You could release the results now.

Prediction: There were no side effects or adverse conditions shown by any of the volunteers, and Thailand has the best vaccine in the world. 

You do know that the results of clinical trials are not issued by those conducting the trials, don't you? The results come from an independent data and safety monitoring board.

Phase 1 clinical trials are typically about dosage range, not about efficacy and therapeutic effect, those evaluations come in Phases 2 and 3. That being so, while it is encouraging that results of Phase 1 are 'promising', it is a long and hard road through to FDA approval, and most fall at the last few hurdles.

7 hours ago, tandor said:

...you think all this orchestrated?

Absolutely, if you consider a kazoo and one-string banjo an orchestra.