3 hours ago, Hummin said:

You know professionals and scientists varns about ivermectin, so there's your proofs it is working! Elementary knownledge 

 

Ivermectin cures everything, even stupidity, at least we could hope

"Ivermectin cures everything, even stupidity, at least we could hope"

 

Yes, very true. But as you could see there are too many lemmings here. If Donald would promote to clean your teeth with a toilet brush...they would follow him🤣

3 hours ago, Tomtomtom69 said:

Let me guess, the Thai CDC will be recommending that Thais wear their beloved masks against this one. 

While in your car  and also during sex with your wife or maybe something else, anyway wear a mask totally “Safe and affective".

2 minutes ago, newbee2022 said:

If Donald would promote to clean your teeth with a toilet brush...they would follow him🤣

Yeah and others to spite the

“orange moron“ would never clean their teeth again.

16 minutes ago, dinsdale said:

From what I'm seeing Ivermectin doesn't have these severe adverse side-effects and in addition is virtually free. This still though is a very uncommon parasitic infection.

You are really without knowledge which I understand.

Look here

https://academic.oup.com/ced/article/47/3/516/6693189

Ivermectin is not listed in the treatments for this disease. Treatment necessitates heavy-duty medications.

6 minutes ago, newbee2022 said:

You are really without knowledge which I understand.

Look here

https://academic.oup.com/ced/article/47/3/516/6693189

This is Big Pharma's approach to treatment. They want to sell their drugs. They don't want an extremely cheap off label product used. I have already posted a couple of links regarding Ivermectin's efficacy in regards to this parasitic infection but there's plenty more scientific papers on the net supporting this approach.

9 minutes ago, dinsdale said:

This is Big Pharma's approach to treatment. They want to sell their drugs. They don't want an extremely cheap off label product used. I have already posted a couple of links regarding Ivermectin's efficacy in regards to this parasitic infection but there's plenty more scientific papers on the net supporting this approach.

Without "Big Pharma" you would be dead probably.

If Donald would not have mentioned it (a person with low IQ and an entirely lack of not only medical knowledge) you would not even think of Ivermectin.

And why to think about it?

It's not by far first line treatment.

And I think this thread is about sand flies and leishmania.

I haven't the clue how Ivermectin come here.

Some beaches have them and others don't. I wonder why?  Tung Wua Len n Chumpon is to be avoided at all cost.

5 minutes ago, newbee2022 said:

Without "Big Pharma" you would be dead probably.

If Donald would not have mentioned it (a person with low IQ and an entirely lack of not only medical knowledge) you would not even think of Ivermectin.

And why to think about it?

It's not by far first line treatment.

And I think this thread is about sand flies and leishmania.

I haven't the clue how Ivermectin come here.

Ivermectin was being used here in Thailand for covid before it was shut down so your reference to Trump is bizarre. As for Ivermectin as a treatment for leishmaniasis this is valid as it's an anti-parasitic drug. I previously posted only the AI overview but here's the more detailed look. Why you have "no clue" is because you don't research.

Ivermectin shows promise as a potential treatment for leishmaniasis, particularly cutaneous leishmaniasis, due to its effectiveness in killing Leishmania parasites and accelerating skin ulcer healing. Studies have demonstrated its efficacy against various Leishmania species, including L. tropica, L. donovani, and L. amazonensis, both in vitro and in vivo. 

 

Here's a more detailed look:

• Mechanism of Action:

  Ivermectin's anti-leishmanial activity is thought to involve its ability to disrupt the parasite's plasma membrane, leading to reduced parasite growth and infection. 

   
• In vitro and in vivo studies:

  Research indicates that ivermectin can significantly reduce the number of parasites in infected macrophages and effectively reduce lesion size and parasite load in animal models. 

   
• Comparison to other treatments:

  In some studies, ivermectin has shown greater efficacy than other drugs used in the treatment of leishmaniasis, such as pentostam, amphotericin B, and rifampicin. 

   
• Potential for drug repositioning:

  Ivermectin is already used for treating other parasitic diseases, making it a promising candidate for "drug repositioning," where an existing drug is repurposed for a new indication. 

   
• Safety and Efficacy:

  Ivermectin is generally considered safe and well-tolerated, with studies showing high cure rates in patients treated with it. 

   
• Formulation advancements:

  Researchers are exploring ways to improve ivermectin's efficacy by incorporating it into sustained-release hydrogels or polymeric micelles to enhance its delivery and therapeutic effects. 

4 minutes ago, KireB said:

Some beaches have them and others don't. I wonder why?  Tung Wua Len n Chumpon is to be avoided at all cost.

That beach has a lot

6 minutes ago, Harrisfan said:

That beach has a lot

You could say that again.

3 minutes ago, KireB said:

You could say that again.

That beach has a lot

20 minutes ago, dinsdale said:

Ivermectin was being used here in Thailand for covid before it was shut down so your reference to Trump is bizarre. As for Ivermectin as a treatment for leishmaniasis this is valid as it's an anti-parasitic drug. I previously posted only the AI overview but here's the more detailed look. Why you have "no clue" is because you don't research.

Ivermectin shows promise as a potential treatment for leishmaniasis, particularly cutaneous leishmaniasis, due to its effectiveness in killing Leishmania parasites and accelerating skin ulcer healing. Studies have demonstrated its efficacy against various Leishmania species, including L. tropica, L. donovani, and L. amazonensis, both in vitro and in vivo. 

 

Here's a more detailed look:

• Mechanism of Action:

  Ivermectin's anti-leishmanial activity is thought to involve its ability to disrupt the parasite's plasma membrane, leading to reduced parasite growth and infection. 

   
• In vitro and in vivo studies:

  Research indicates that ivermectin can significantly reduce the number of parasites in infected macrophages and effectively reduce lesion size and parasite load in animal models. 

   
• Comparison to other treatments:

  In some studies, ivermectin has shown greater efficacy than other drugs used in the treatment of leishmaniasis, such as pentostam, amphotericin B, and rifampicin. 

   
• Potential for drug repositioning:

  Ivermectin is already used for treating other parasitic diseases, making it a promising candidate for "drug repositioning," where an existing drug is repurposed for a new indication. 

   
• Safety and Efficacy:

  Ivermectin is generally considered safe and well-tolerated, with studies showing high cure rates in patients treated with it. 

   
• Formulation advancements:

  Researchers are exploring ways to improve ivermectin's efficacy by incorporating it into sustained-release hydrogels or polymeric micelles to enhance its delivery and therapeutic effects. 

Sorry, I'm too tired to fight ignorance. Just inform yourself (read my link by a reliable source) about first line treatment in case of leishmania.

Your statement about ivermectin in this case is sorry... ridiculous. 

Again: it's about leishmania. 

Good day

 

23 hours ago, Puccini said:

 

What does Ivermectin have to do with this topic?

His horse has worms.....

5 minutes ago, newbee2022 said:

Sorry, I'm too tired to fight ignorance. Just inform yourself (read my link by a reliable source) about first line treatment in case of leishmania.

Your statement about ivermectin in this case is sorry... ridiculous. 

Again: it's about leishmania. 

Good day

 

What part of this do you not understand? Ignorance sir would seem not to be from my side.

Ivermectin shows promise as a potential treatment for leishmaniasis, particularly cutaneous leishmaniasis, due to its effectiveness in killing Leishmania parasites and accelerating skin ulcer healing. 

12 minutes ago, simon43 said:

His horse has worms.....

Over 1.5 billion doses of Ivermectin have been taken by humans. 

49 minutes ago, dinsdale said:

What part of this do you not understand? Ignorance sir would seem not to be from my side.

Ivermectin shows promise as a potential treatment for leishmaniasis, particularly cutaneous leishmaniasis, due to its effectiveness in killing Leishmania parasites and accelerating skin ulcer healing. 

At the moment I can't see any country which will use Ivermectin in case of Leishmania. As first line treatments...check my link. 

This thread is not about Ivermectin!!. You're free to start a new one.

On 4/25/2025 at 6:35 PM, steven100 said:

always hated sandflies ....   stinging little critters .....    100 million of them in Australia.

You counted?

6 minutes ago, newbee2022 said:

At the moment I can't see any country which will use Ivermectin in case of Leishmania. As first line treatments...check my link. 

This thread is not about Ivermectin!!. You're free to start a new one.

The thread is about leishmaniasis and as such discussing treatments for this is valid. Although Ivermectin isn't being used "officially", as pointed out research is being carried out and the results are positive. What's wrong with you. Here's an off license extremely cheap drug that research is saying is highly effective. Why are you so stubborn not to recognise this. 

13 minutes ago, still kicking said:

On 4/25/2025 at 5:35 PM, steven100 said:

always hated sandflies ....   stinging little critters .....    100 million of them in Australia.

You counted?

 

As of 2025 - there are 26.66 Million stinging little critters in Australia... 

1 hour ago, KireB said:

Some beaches have them and others don't. I wonder why?  Tung Wua Len n Chumpon is to be avoided at all cost.

As I was reading the story, I thought immediately of Tung Wua Laen in Chumphon. Stayed their several times in 2020 and since. Walked on the beach each day. Got many sandfly bites. 

 

I saw this video about a year ago. You definitely don't want to get Leishmaniasis. I'd never heard of it before. Scary!!! 

 

 

On 4/25/2025 at 3:33 PM, Puccini said:

 

According to the news, article Dr Jurai Wongsawat recommends an insect repellent as a protective measure against sandfly bites, not Ivermectin.

 

On 4/25/2025 at 3:33 PM, Puccini said:

 

According to the news, article Dr Jurai Wongsawat recommends an insect repellent as a protective measure against sandfly bites, not Ivermectin.

 

 

Had enough of experts ...

they suck you and later want money.

On 4/25/2025 at 11:40 AM, johng said:

Where can we get some Ivermectin from ?

Ivermectin doesn't work - Leishmania is not a worm — it's a protozoan parasite, and it behaves very differently from parasites that ivermectin normally kills.

On 4/25/2025 at 2:33 PM, Puccini said:

 

According to the news, article Dr Jurai Wongsawat recommends an insect repellent as a protective measure against sandfly bites, not Ivermectin.

the former prevents bites, the latter does nothing for Leishmaniasis once you've got it.

While I personally despise sandflies and nearly all flying insects, I question if an urgent health warning is truly appropriate from two deaths nationwide?

 

Is this just a bit of over panic? It's always a good idea to wear some repellent anyway, because of the mosquitoes and dengue, though I do not like using traditional insect spray i mix my own with a blend of 50% eucalyptus, 25% citronella and 25% lemongrass essential oils. It's very effective and the smell is fairly pleasant. And it not only keeps away mosquitoes, it keeps away flies and all other flying insects they hate it. 

17 hours ago, KhunLA said:

I wouldn't trust anything the CDC states anymore.   They don't seem to recommend any inexpensive treatments, just high end big pharma drugs ... IMHO

 

I agree and I took pains not to link to anything from the CDC.

17 hours ago, johng said:

 

Ivermectin is a very good anti parasitic medication...do some of your own research but here is just a little clue.

https://www.nobelprize.org/prizes/medicine/2015/press-release/

 

 

Thank you for the link, but I cannot find any mention of Invermectin in that article.

17 hours ago, KhunLA said:

Ivermectin apparently can be used, certainly wouldn't hurt to try it.

 

From what I've learnt by browsing the Internet since seeing this topic, there are different types of leishmaniasis and not all respond to the same type of treatment. 

 

I have also seen emphasis given to early analysis and diagnosis of leishmaniasis, followed by appropriate treatment.

 

With symptoms showing after a sandfly bite, if I would even know that it was a sandfly, I would not trust myself to self-analyse, self-diagnose and initiate self-treatment.