Two nasal spray COVID-19 vaccines under development by Thailand’s BIOTEC

[webfact]

A patient receives a nasal spray vaccine for the H1N1 virus in Maryland in 2009. AFP PHOTO / Tim Sloan (Photo by TIM SLOAN / AFP)

 

Thai virologists, at the National Centre for Genetic Engineering and Biotechnology (BIOTEC), have been developing two candidate nasal spray vaccines, or vaccine inhalers, which they hope will provide an option in the prevention of COVID-19 infection, not just prevent severe symptoms.

 

Dr. Anan Jongkaewwattana, director of Veterinary Health Innovation and Management Research Group told Thai PBS that most COVID-19 vaccines are being administered via intramuscular injections, to stimulate antibodies in the blood stream, but not enough in the nasal passage to prevent the virus invading the body, adding that COVID-19 enters the body through respiratory system.

 

The first inhaled vaccine developed at BIOTEC was the Adenovirus vaccine, with financial support from the National Vaccine Institute. Two doses of the vaccine were administered to mice injected with COVID-19 and it was discovered that the mice did not die or fall sick and they ate as normal with their weight remaining stable.

 

Full story: https://www.thaipbsworld.com/two-nasal-spray-covid-19-vaccines-under-development-by-thailands-biotec/

 

-- © Copyright Thai PBS 2021-08-07

 

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[bdenner]

That should get my dreaded Hay Fever condition excited!

[Gottfrid]

They always have something in the pipeline, but later it´s all drained out to never be heard about.

[mtls2005]

5 hours ago, webfact said:

Two doses of the vaccine were administered to mice injected with COVID-19 and it was discovered that the mice did not die

 

Phew.

 

 

My mouse is relieved.

 

Welcome to Krazy Town.

 

 

 

[metisdead]

22 minutes ago, Oww said:

Not one "news" report of the heinous MURDER of a tourist in the Phuket 'sandbox'! 

Disgusting protectionism for tourist dollars! 

 

You will find some topics about that in the Phuket News forum. 

[mikebell]

1 hour ago, bdenner said:

That should get my dreaded Hay Fever condition excited!

I stopped suffering when I moved here from UK.  I had just found a cure after years of misery;' Kenilogue long acting steroid injection' instantly gave me at least a month's protection. (May have mis-spelled the maker's name.)

[internationalism]

"Dr. Anan Jongkaewwattana, director of Veterinary Health Innovation"

I agree that animals should be also protected from diseases, because they might cross to humans, but so far there is no indication it's happening with covid.

Altimmune the nasal spray vax was abandoned in the USA at the end of June. Looks, like it's not that simple, that covid is airborne and the best way is vax through inhallation.

The great majority of vax are through injection. Very few are pills.

https://ir.altimmune.com/news-releases/news-release-details/altimmune-announces-update-adcovidtm-phase-1-clinical-trial

 

so good luck with trying. Possibly would be more efficient to concentrate on one spray vax, than on many at the same time, because likely it will be wasted work

 

Edited August 7, 2021 by internationalism

[khunPer]

Israel also seems to be fairly close to a possible Covid-medicine cure...

 

88 patients, 0 intubated: Israeli ‘precision’ COVID drug wrapping up early trial

Placebo study still to come, but inventor says medication ‘could be a game changer’ after around 9 out of 10 participants in Greek trial are released from hospital within 5 days...

Link to article HERE.

[Soikhaonoiken]

14 hours ago, Gottfrid said:

They always have something in the pipeline, but later it´s all drained out to never be heard about.

Yep.... Last week it was the turn of the witch doctors 

[Jan de Uitvreter]

Meanwhile a couple of months ago in the Netherlands:

 

https://www.intravacc.nl/news/intravacc-announces-positive-pre-clinical-data-intranasal-sars-cov-2-candidate-vaccine/

[AwwYesNice1]

Thai so smart.

[Caldera]

I'm somewhat suspicious of a vaccine that the best they can say about seems to be, "the mice didn't die".

[ArcticFox]

5 hours ago, Caldera said:

I'm somewhat suspicious of a vaccine that the best they can say about seems to be, "the mice didn't die".

Or patients weren't intubated.

Wake me up when the first company declares via trial data that their covid vaccine provides full immunity like a small pox, measles, or polio vaccine.

[1FinickyOne]

On 8/7/2021 at 8:05 AM, Gottfrid said:

They always have something in the pipeline, but later it´s all drained out

just tilt your head back... 

[ArcticFox]

20 hours ago, khunPer said:

Israel also seems to be fairly close to a possible Covid-medicine cure...

 

88 patients, 0 intubated: Israeli ‘precision’ COVID drug wrapping up early trial

Placebo study still to come, but inventor says medication ‘could be a game changer’ after around 9 out of 10 participants in Greek trial are released from hospital within 5 days...

Link to article HERE.

Actually this is a treatment and not a vaccine.  As a treatment this does look promising. 

[zzaa09]

10 hours ago, AwwYesNice1 said:

Thai so smart.

Secretly clever. 

 

[Elkski]

So mice, dogs, deer can harbor covid?   Hasn't it also been found in other zoo animals? Another reason to get rid of soi dogs. 

What was the DR comment? " We are not slow". More worried about face.   Thailand is a good place for clinical trials right now.  Any coincidence? 

[metisdead]

Some off topic posts about Windows XP computer programs have been removed. 

[Denim]

On 8/7/2021 at 3:20 AM, webfact said:

Dr. Anan Jongkaewwattana, director of Veterinary Health Innovation

Who usually works with animals but has decided to help out anyway and has been working doggedly to prevent a catastrophe before herd immunity can kick in. In field experiments , mice have remained stable and none have bought the farm.

 

 

Edited August 8, 2021 by Denim

[tomacht8]

On 8/7/2021 at 3:30 PM, khunPer said:

Israel also seems to be fairly close to a possible Covid-medicine cure...

 

88 patients, 0 intubated: Israeli ‘precision’ COVID drug wrapping up early trial

Placebo study still to come, but inventor says medication ‘could be a game changer’ after around 9 out of 10 participants in Greek trial are released from hospital within 5 days...

Link to article HERE.

Synairgen also working on a cure.

https://www.synairgen.com/covid-19/

[digibum]

I wish Thailand (or the media) would quit embarrassing itself by making these outlandish claims.  
 

It’s not that Thais are dumb, it’s that other countries and companies have way, way, way more resources to throw at these problems. 
 

Like what happened to the vaccine Thai scientists were working on before Pfizer or any of the major drug companies had a workable product?  
 

Silence?  Crickets?  
 

This isn’t like making up tourism numbers. Real scientists are going to check your work.