Popular Post snoop1130 Posted August 16, 2021 Popular Post Share Posted August 16, 2021 BANGKOK, Aug 16 (TNA) – The ChulaCov19 vaccine proved to be as effective as the Pfizer vaccine when it comes to antibody stimulation to fight COVID-19, according to its developers. King Chulalongkorn Memorial Hospital, the Thai Red Cross Society and the Chula Vaccine Research Center announced the achievement of their ChulaCov19, Thailand’s first mRNA COVID-19 vaccine, after the first phase of its clinical trials with Thai volunteers on June 24. They developed the vaccine together with the University of Pennsylvania. Full Story: https://tna.mcot.net/english-news-759426 -- © Copyright TNA 2021-08-166 - Whatever you're going through, the Samaritans are here for you - Follow ASEAN NOW on LINE for breaking COVID-19 updates 3 1 13 Link to comment Share on other sites More sharing options...
Popular Post 2long Posted August 16, 2021 Popular Post Share Posted August 16, 2021 "announced the achievement .. after the first phase of its clinical trials" Well then if they want to go ahead and announce it, there's no need for further trials! 2 2 Link to comment Share on other sites More sharing options...
Popular Post fondue zoo Posted August 16, 2021 Popular Post Share Posted August 16, 2021 Will the Chupa Chups vaccine be peer reviewed, surely the US connection will want something like that to happen? 1 3 Link to comment Share on other sites More sharing options...
Popular Post Golden Triangle Posted August 16, 2021 Popular Post Share Posted August 16, 2021 22 minutes ago, ezzra said: If it's better than the the Sino rubbish and the other Sino cr*p than go for it, but i'm skeptical as to how a vax was developed so quickly as vaccines takes many months if not years to prefect in human trials and here Presto, out of a blue, Thailand has it's own vax.. Amazing... Like most things Thai or Chinese, they copied someone else's work, plenty of articles on here to substantiate what I have said, no I'm not gonna post links, if you've been here long enough you will have seen them, do your own research ???? 10 2 1 Link to comment Share on other sites More sharing options...
Popular Post Stocky Posted August 16, 2021 Popular Post Share Posted August 16, 2021 19 minutes ago, fondue zoo said: Will the Chupa Chups vaccine be peer reviewed, surely the US connection will want something like that to happen? Yes this is just phase 1, where a small groups of people receive the trial vaccine. Next is phase 2 and the trial is expanded to test within a more varied group of volunteers. Should it continue to perform well then it goes to phase 3, a large scale testing for safety and efficacy, this stage is double blind, neither the testers nor the subjects know if they're getting the vaccine or a placebo. It has a long way to go yet. 8 2 Link to comment Share on other sites More sharing options...
Popular Post DonniePeverley Posted August 16, 2021 Popular Post Share Posted August 16, 2021 (edited) Is this kind of like Apple doing a mobile phone, and then you have some Chinese phones that come out and do an almost similar exact phone, literally all the technology the same - except they change volume button to the other side meaning it's not the same. Edited August 16, 2021 by DonniePeverley 4 1 3 Link to comment Share on other sites More sharing options...
Popular Post RotBenz8888 Posted August 16, 2021 Popular Post Share Posted August 16, 2021 17 minutes ago, DonniePeverley said: Is this kind of like Apple doing a mobile phone, and then you have some Chinese phones that come out and do an almost similar exact phone, literally all the technology the same - except they change volume button to the other side meaning it's not the same. I remember once at MBK, I was looking at a Sony-Ericsson phone, and asked the sales guy if it was original. He said " it's better than the original!" ???? 2 11 Link to comment Share on other sites More sharing options...
4MyEgo Posted August 16, 2021 Share Posted August 16, 2021 1 hour ago, fondue zoo said: Will the Chupa Chups vaccine be peer reviewed, surely the US connection will want something like that to happen? I wondering if it comes in different flavours and can be taken orally ? 1 Link to comment Share on other sites More sharing options...
Popular Post Nojohndoe Posted August 16, 2021 Popular Post Share Posted August 16, 2021 A good promising start! I am left wondering why a comparison to Pfizer alone? Is Moderna's product somehow so inferior as to being a comparative? The technology involved in mRNA vaccine development is not actually so new in medical research with many documented papers describing the science of it. Independently achieving a result using a published technological process is not copying or stealing. And under the circumstances of the pandemic situation where such vaccines are being heralded as global salvation who cares when the pandemic is costing the well being of whole nations and the societies in them? 3 1 Link to comment Share on other sites More sharing options...
Nojohndoe Posted August 16, 2021 Share Posted August 16, 2021 Just to distract attention a little Marbug Virus has surfaced again. Enjoy. Link to comment Share on other sites More sharing options...
Popular Post placeholder Posted August 16, 2021 Popular Post Share Posted August 16, 2021 1 hour ago, Golden Triangle said: Like most things Thai or Chinese, they copied someone else's work, plenty of articles on here to substantiate what I have said, no I'm not gonna post links, if you've been here long enough you will have seen them, do your own research ???? Maybe you're hoping that your explicit refusal to provide evidence provides you with a kind of inoculation against being asked to back up your claims? Unless you were getting your info from some particular garbage pile of a webite, there aren't "plenty of article on here to substantiate" what you claim. In fact, as Nojohndoe pointed out, nobody gets to claim such originality. Developing a vaccine has been a project that depends on research in many countries. You have no idea what went into the Thai project. And the fact that it was possible to be done in Thailand proves that there is sophisticated technical capability in Thailand. 3 1 3 Link to comment Share on other sites More sharing options...
Caldera Posted August 16, 2021 Share Posted August 16, 2021 Up there with the very best of them, Thailand is well and truly a bioscience hub (among countless other hubs). 2 Link to comment Share on other sites More sharing options...
Popular Post placeholder Posted August 16, 2021 Popular Post Share Posted August 16, 2021 4 hours ago, ezzra said: If it's better than the the Sino rubbish and the other Sino cr*p than go for it, but i'm skeptical as to how a vax was developed so quickly as vaccines takes many months if not years to prefect in human trials and here Presto, out of a blue, Thailand has it's own vax.. Amazing... I hate all this newfangled so-called science stuff too. When I was a boy my mom knitted. me vaccines 4 Link to comment Share on other sites More sharing options...
Popular Post placeholder Posted August 16, 2021 Popular Post Share Posted August 16, 2021 17 minutes ago, Golden Triangle said: Thai man invents pollution free generator that doesn’t need fuel Image: INN A Thai man says he has invented an environmentally friendly power generator that can generate electricity for up to 8 hours without using fuel. Here you go, this sits alongside all the other " inventions " that over the years would be claimed by various groups, students etc, only to be found later that as usual the methods have been used by others prior to Thais to achieve the same goal, who was it came up with the wind up radio & other stuff ?? Read the whole thread is my advice. On the one hand you can't be bothered to locate one of the "plenty of articles" that would back up your assertion that this is just copycat work. On the other you apparently can be bothered to share an entirely irrelevant article. Thanks for providing confirmation of the emptiness of your assertion. 5 1 Link to comment Share on other sites More sharing options...
Popular Post bkkcanuck8 Posted August 16, 2021 Popular Post Share Posted August 16, 2021 5 hours ago, 2long said: "announced the achievement .. after the first phase of its clinical trials" Well then if they want to go ahead and announce it, there's no need for further trials! Actually, the Phase I results will usually have sufficient information to indicate whether the vaccine will cause enough of an immune response to indicate there is a good chance that it will make it through the 3 phases. The primary difference in the 3 phases are a staged increase in healthy individuals testing the vaccine (Phase I - maybe up to 100 volunteers; Phase II - maybe several hundred; Phase III - maybe a few thousand. Each of them you are getting a more diverse and larger sample set to work on. The same sort of news release was given after Phase I of the COVID vaccines in the United States. As the sample set increases things may change, but even with 100 you should have a good indication of about where the efficacy will end up (with a larger margin of error). Later phases are more about figuring out the dose size and getting a better indication of side effects etc. 4 1 Link to comment Share on other sites More sharing options...
Popular Post shdmn Posted August 16, 2021 Popular Post Share Posted August 16, 2021 (edited) Sure seems to be a lot of virologists on this message board who love to give their expert opinions...that they pull out of thin air and that always seems to conclude that THAilAnd BaD. Edited August 16, 2021 by shdmn 2 2 Link to comment Share on other sites More sharing options...
Rampant Rabbit Posted August 16, 2021 Share Posted August 16, 2021 (edited) I trust nothing coming out of Thailand in any way. Edited August 16, 2021 by Rampant Rabbit 1 Link to comment Share on other sites More sharing options...
Popular Post Rampant Rabbit Posted August 16, 2021 Popular Post Share Posted August 16, 2021 2 hours ago, shdmn said: Sure seems to be a lot of virologists on this message board who love to give their expert opinions...that they pull out of thin air and that always seems to conclude that THAilAnd BaD. Maybe its all those anouncements of something new that The Thais tell us they have invented only for someone to post a verified link to it being done donkeys years before like cloud seeding. 4 Link to comment Share on other sites More sharing options...
Popular Post webfact Posted August 16, 2021 Popular Post Share Posted August 16, 2021 Early study shows ChulaCOV-19 vaccine as effective as Pfizer By Tanakorn Sangiam BANGKOK (NNT) - The Phase 1 trial of Thailand’s homegrown mRNA COVID-19 vaccine ChulaCOV-19, suggests the candidate vaccine can help the body elicit the same level of antibody response as the Pfizer-BioNTech, along with much easier storage requirements. The researchers are aiming for this Thai-made vaccine to be available next year as a booster shot for Thai people. King Chulalongkorn Memorial Hospital and the Faculty of Medicine at Chulalongkorn University, today announced a promising preliminary result from the Phase 1 clinical trial of the ChulaCOV-19 vaccine, Thailand’s homegrown COVID-19 vaccine developed using the much anticipated mRNA technology. Prof Dr Kiat Ruxrungtham, director of the Chula Vaccine Research Center (Chula VRC), said today the Phase 1 trial conducted with 36 volunteers aged 18-55 years old, showed the trial vaccine can help the body build a level of antibody response similar to the Pfizer-BioNTech vaccine, developed using the same mRNA technology. The volunteers have been constantly monitored and tested for their antibody responses after receiving two doses of ChulaCOV-19 from world-class laboratories. Preliminary results from this study show the vaccine candidate is 94% efficacious in preventing SARS-CoV-2 attachment to human cells, the same level as the Pfizer-BioNTech vaccine. In comparison, the viral vector vaccine from AstraZeneca has this particular efficacy rate at 84%, while the inactivated vaccine from Sinovac is at 75%. The minimum threshold of research was only 68%. In terms of safety, all 36 volunteers reported no adverse events following vaccination. Mild to moderate side effects similar to those of other vaccines were observed, with most of the symptoms improving after 1-3 days. The researchers have concluded that data from the Phase 1 study shows the ChulaCOV-19 candidate vaccine can help the body in eliciting a high level of antibody response effective in preventing illnesses from the wild type SARS-CoV-2, as well as the Alpha, Beta, Gamma, and Delta variants of concern. With performance expected to be similar to the Pfizer-BioNTech vaccine, this Thai-made mRNA vaccine does not come with ultra cold storage and transportation requirements. The vaccine has been designed to remain potent and stable at a normal refrigerator temperature of 2-8 degree celsius for three months, or at the regular temperature of an air conditioned room for 14 days. With promising results from the initial trial stage, the researchers are now going ahead with a Phase 2 trial involving more volunteers. The team will be selecting the appropriate dosage for Phase 2 at the end of this week, while the actual study is expected to commence on 25th August. In this phase, researchers will be making a head-to-head comparison between volunteers receiving ChulaCOV-19, and volunteers receiving Pfizer-BioNTech vaccine supplied by the Ministry of Public Health. If all goes well, the team expects to have this Thai-made mRNA vaccine available to the general public by April 2022, mainly as a booster shot for fully vaccinated people. The researchers are also working on a second-generation and third-generation vaccine in response to newer variants. Prof Dr Kiat said the vaccine project still needs more fluid funding from related agencies, while urging the government, private sector, and the general public to consider a new protocol for vaccine authorization to determine at what stage of the study the candidate vaccine could receive emergency regulatory approval. The Thai Food and Drugs Administration is now brainstorming this new protocol, which is expected to be released next month. The vaccine project still needs to rely on a capable manufacturer which can produce doses in bulk before the end of this year, as well as a clarified advance vaccine procurement policy from the government. -- © Copyright NNT 2021-08-17 - Whatever you're going through, the Samaritans are here for you - Follow ASEAN NOW on LINE for breaking COVID-19 updates 4 3 Link to comment Share on other sites More sharing options...
Popular Post shdmn Posted August 16, 2021 Popular Post Share Posted August 16, 2021 (edited) 49 minutes ago, Rampant Rabbit said: Maybe its all those anouncements of something new that The Thais tell us they have invented only for someone to post a verified link to it being done donkeys years before like cloud seeding. Show us your verified links then. I can tell you first hand that a lot of the info some here are spewing is a bunch of made up nonsense. Don't even get me started with the constant "Phuket sandbox is going to fail" nonsense. You don't hear much of that here anymore because a lot of hotels are starting to fill up, as expected. And it's still ultra low season. Wait till we get into Oct/Nov. So the doom mongers do what they do best, move on to the next shiny object to complain about instead of admit they were wrong, and they are almost ALWAYS wrong. Now they are beaking off about lack of vaccines. I can guarantee you that will gradually improve. It already has quite a bit. So the perpetually wrong doom mongers will just move on from that eventually. Edited August 16, 2021 by shdmn 1 2 2 Link to comment Share on other sites More sharing options...
placeholder Posted August 16, 2021 Share Posted August 16, 2021 3 hours ago, bkkcanuck8 said: Actually, the Phase I results will usually have sufficient information to indicate whether the vaccine will cause enough of an immune response to indicate there is a good chance that it will make it through the 3 phases. The primary difference in the 3 phases are a staged increase in healthy individuals testing the vaccine (Phase I - maybe up to 100 volunteers; Phase II - maybe several hundred; Phase III - maybe a few thousand. Each of them you are getting a more diverse and larger sample set to work on. The same sort of news release was given after Phase I of the COVID vaccines in the United States. As the sample set increases things may change, but even with 100 you should have a good indication of about where the efficacy will end up (with a larger margin of error). Later phases are more about figuring out the dose size and getting a better indication of side effects etc. CureVac COVID vaccine let-down spotlights mRNA design challenges Two vaccines made using messenger RNA (mRNA) have proved spectacularly successful at warding off COVID-19, but a third mRNA-based candidate has flopped in a final-stage trial, according to an initial report released this week. Researchers are now asking why — and some think that choices about the type of mRNA chemistry used might be to blame. Any insight could help to guide the future design of mRNA vaccines against COVID-19 or other diseases. https://www.nature.com/articles/d41586-021-01661-0 1 Link to comment Share on other sites More sharing options...
placeholder Posted August 16, 2021 Share Posted August 16, 2021 3 hours ago, bkkcanuck8 said: Actually, the Phase I results will usually have sufficient information to indicate whether the vaccine will cause enough of an immune response to indicate there is a good chance that it will make it through the 3 phases. The primary difference in the 3 phases are a staged increase in healthy individuals testing the vaccine (Phase I - maybe up to 100 volunteers; Phase II - maybe several hundred; Phase III - maybe a few thousand. Each of them you are getting a more diverse and larger sample set to work on. The same sort of news release was given after Phase I of the COVID vaccines in the United States. As the sample set increases things may change, but even with 100 you should have a good indication of about where the efficacy will end up (with a larger margin of error). Later phases are more about figuring out the dose size and getting a better indication of side effects etc. CureVac COVID vaccine let-down spotlights mRNA design challenges Two vaccines made using messenger RNA (mRNA) have proved spectacularly successful at warding off COVID-19, but a third mRNA-based candidate has flopped in a final-stage trial, according to an initial report released this week. Researchers are now asking why — and some think that choices about the type of mRNA chemistry used might be to blame. Any insight could help to guide the future design of mRNA vaccines against COVID-19 or other diseases. https://www.nature.com/articles/d41586-021-01661-0 After I posted this I decided to actually read the whole article. It turns out that the Curevac vaccine generated low amounts of antibodies in those who were inoculated. Unlike the Chula vaccine. So that's a positive sign. 1 Link to comment Share on other sites More sharing options...
Skeptic7 Posted August 17, 2021 Share Posted August 17, 2021 Yeah sure it can. ???? Link to comment Share on other sites More sharing options...
smedly Posted August 17, 2021 Share Posted August 17, 2021 reading that article Thailand is claiming to have developed an mRNA vaccine that is performing better than any other vaccine in the world right now, at least that is how it is written what am I missing - probably a lot was waiting for the - "but" it requires a full litre dose per jab 1 Link to comment Share on other sites More sharing options...
Popular Post mfd101 Posted August 17, 2021 Popular Post Share Posted August 17, 2021 Well, if they can do it, good on them and one up to them. If not, then not. We'll know by next year some time. 3 Link to comment Share on other sites More sharing options...
placeholder Posted August 17, 2021 Share Posted August 17, 2021 16 minutes ago, smedly said: reading that article Thailand is claiming to have developed an mRNA vaccine that is performing better than any other vaccine in the world right now, at least that is how it is written what am I missing - probably a lot was waiting for the - "but" it requires a full litre dose per jab Another compulsive Thai-basher. 2 Link to comment Share on other sites More sharing options...
scorecard Posted August 17, 2021 Share Posted August 17, 2021 10 hours ago, Nojohndoe said: A good promising start! I am left wondering why a comparison to Pfizer alone? Is Moderna's product somehow so inferior as to being a comparative? The technology involved in mRNA vaccine development is not actually so new in medical research with many documented papers describing the science of it. Independently achieving a result using a published technological process is not copying or stealing. And under the circumstances of the pandemic situation where such vaccines are being heralded as global salvation who cares when the pandemic is costing the well being of whole nations and the societies in them? Good point. In a pure structured research scenario there would be many required diverse broad protocols/comparisons. Seems to me that's not what we have in this case. In fact I'm guessing that because Pfizer is the current 'flavor of the month/the most popular' (to the Thai 'professionals', including the most vocal who are politicians who know nothing about the real subject at hand, rather then a respected team of aligned qualified experienced respected medical researchers) Pfizer is therefore the only comparison. Sad, when millions of Thais struggle* to get even a first jab. (*many of my Thai relatives have registered online, registered by hand at various venues and institutes, called numerous published phone numbers and more, all with no result. Or get registered and even get bookings which eventually 'evaporate'. They remain lost and confused while they read/see on TV stories about hi-so folks, politicians aunts & uncles etc., getting jabs. My own Thai son and his Thai wife went to a medical institute which was advertising dates and times for jabs, they registered together and took smartphone photos of the documents they completed and handed in. Two weeks later my son got an SMS with date/time 5 days later. He attended and got his first shot. He asked about his wife, and showed his smartphone photos of her submission, the admin. folks claimed his wife had never registered and refused to discuss further. She's still registering frequently, getting nowhere.) 1 Link to comment Share on other sites More sharing options...
steven100 Posted August 17, 2021 Share Posted August 17, 2021 12 hours ago, fondue zoo said: Will the Chupa Chups vaccine be peer reviewed, surely the US connection will want something like that to happen? Does this mean Expatvac will be using Chupa Chups vax and they are calling for TV expat volunteer's who are over 60 and possibly pregnant .... Link to comment Share on other sites More sharing options...
spermwhale Posted August 17, 2021 Share Posted August 17, 2021 7 hours ago, placeholder said: I hate all this newfangled so-called science stuff too. When I was a boy my mom knitted. me vaccines You are skeptical because you don't understand the science of it. But do you understand the science of any other vaccine or medicine you use? They developed fast because so many of the world's largest pharmaceutical companies started working on vaccines and threw all they had into it. Many failed. Many have never made it to clinical trials and you never heard of those efforts. The first people who were involved in the initial clinical trials got their shots more than a year ago. Still no long term effects are showing. And before you say one year is not a long term mind you after a few weeks the vaccines are no longer in our bodies. They have prepped our bodies to fight COIVD-19. No vaccine on the market has had long-term effects where people have adverse effects years and years later. Many vaccines including the COVID-19 ones have had adverse effects in rare cases but they happened shortly after inoculation. 1 1 Link to comment Share on other sites More sharing options...
dougiemac52 Posted August 17, 2021 Share Posted August 17, 2021 12 hours ago, ezzra said: If it's better than the the Sino rubbish and the other Sino cr*p than go for it, but i'm skeptical as to how a vax was developed so quickly as vaccines takes many months if not years to prefect in human trials and here Presto, out of a blue, Thailand has it's own vax.. Amazing... It will be Pfizer with something else Link to comment Share on other sites More sharing options...
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