Ivermectin

[Harry Om]

11 hours ago, Rookiescot said:

Guys its your body and you can do as you like with it but why would a medicine for deworming livestock work on a virus?

It simply does not make sense.

 

Many drugs have multiple uses. Ivermectin was being looked at as a possible antiviral before covid hit, but unfortunately now it's become caught up in the usual pi55ing contests.

 

As for the mechanism for how it might work, there's lots of ongoing research, for instance;

 

"To date, the most accepted mechanism of action for ivermectin against SARS-CoV-2 is inhibition of the nuclear import of viral proteins and RNA, as has been found for HIV-1 and dengue [9]. However, it has also been reported that ivermectin has a potentially inhibitory effect against other viruses such as flaviviruses by blocking the NS3 helicase [10]. Additionally, it has been reported that it can dock in a thermodynamically favorable manner, and with theoretical potential to inhibit other structural and functional proteins associated with SARS-CoV-2 [11]."

 

"The SARS-CoV-2 pandemic has accelerated the study of existing drugs. The mixture of homologs called ivermectin (avermectin-B1a [HB1a] + avermectin-B1b [HB1b]) has shown antiviral activity against SARS-CoV-2 in vitro. However, there are few reports on the behavior of each homolog. We investigated the interaction of each homolog with promising targets of interest associated with SARS-CoV-2 infection from a biophysical and computational-chemistry perspective using docking and molecular dynamics. We observed a differential behavior for each homolog, with an affinity of HB1b for viral structures, and of HB1a for host structures considered. The induced disturbances were differential and influenced by the hydrophobicity of each homolog and of the binding pockets. We present the first comparative analysis of the potential theoretical inhibitory effect of both avermectins on biomolecules associated with COVID-19, and suggest that ivermectin through its homologs, has a multiobjective behavior. "

https://www.sciencedirect.com/science/article/pii/S0301462221001599?via%3Dihub

[canthai55]

Just more Internet Einsteins quacking about a subject they know absolutely nothing about.

Ivermectin - along with many many other drugs - may well have other uses than the "Just for Horses" BS spouted by Big Pharma and their cohorts in the FDA.

Ongoing research is showing this to be true, but you can bet your Gluteus Maximus that all the stops are being pulled out to have this stopped, or discredited.

No money to be made by the big boys.

Much research has been stopped this way - and it will continue.

[heybruce]

5 hours ago, Harry Om said:

"If you read the entire article (it's short)".

Comments like this are a childish way of discussing serious issues.

 

Why not the same increase? Later studies identified that the problem was genetic, so it was likely to occur in Scandinavian countries and not elsewhere. The other studies chose cohorts that did not include that group, that's why you didn't see any increase.

So you agree that the problem of an unquantified correlation between AZ vaccinations and narcolepsy is an isolated genetic issue and not a widespread problem.  Good.

[heybruce]

5 hours ago, canthai55 said:

Just more Internet Einsteins quacking about a subject they know absolutely nothing about.

Ivermectin - along with many many other drugs - may well have other uses than the "Just for Horses" BS spouted by Big Pharma and their cohorts in the FDA.

Ongoing research is showing this to be true, but you can bet your Gluteus Maximus that all the stops are being pulled out to have this stopped, or discredited.

No money to be made by the big boys.

Much research has been stopped this way - and it will continue.

"Ongoing research is showing this to be true, but you can bet your Gluteus Maximus that all the stops are being pulled out to have this stopped, or discredited. "

 

I'll take that bet.  Show us evidence that somebody, anybody, is obstructing research into the effectiveness of ivermectin in treating Covid 19 infections.

[heybruce]

5 hours ago, Harry Om said:

Many drugs have multiple uses. Ivermectin was being looked at as a possible antiviral before covid hit, but unfortunately now it's become caught up in the usual pi55ing contests.

 

As for the mechanism for how it might work, there's lots of ongoing research, for instance;

 

"To date, the most accepted mechanism of action for ivermectin against SARS-CoV-2 is inhibition of the nuclear import of viral proteins and RNA, as has been found for HIV-1 and dengue [9]. However, it has also been reported that ivermectin has a potentially inhibitory effect against other viruses such as flaviviruses by blocking the NS3 helicase [10]. Additionally, it has been reported that it can dock in a thermodynamically favorable manner, and with theoretical potential to inhibit other structural and functional proteins associated with SARS-CoV-2 [11]."

 

"The SARS-CoV-2 pandemic has accelerated the study of existing drugs. The mixture of homologs called ivermectin (avermectin-B1a [HB1a] + avermectin-B1b [HB1b]) has shown antiviral activity against SARS-CoV-2 in vitro. However, there are few reports on the behavior of each homolog. We investigated the interaction of each homolog with promising targets of interest associated with SARS-CoV-2 infection from a biophysical and computational-chemistry perspective using docking and molecular dynamics. We observed a differential behavior for each homolog, with an affinity of HB1b for viral structures, and of HB1a for host structures considered. The induced disturbances were differential and influenced by the hydrophobicity of each homolog and of the binding pockets. We present the first comparative analysis of the potential theoretical inhibitory effect of both avermectins on biomolecules associated with COVID-19, and suggest that ivermectin through its homologs, has a multiobjective behavior. "

https://www.sciencedirect.com/science/article/pii/S0301462221001599?via%3Dihub

Good to know.  When the "ongoing research" results in proven effectiveness and the treatment passes the required safety and effectiveness trials, we'll all be happy to include ivermectin in the options for treating Covid 19 infections.

[Rimmer]

Off topic post removed

[Danderman123]

Why ivermectin should not be used to prevent or treat COVID-19

 

you can follow the guidance of the American Medical Association, or some random person on the internet. Up to you.

 

 

[Will B Good]

1 minute ago, Danderman123 said:

Why ivermectin should not be used to prevent or treat COVID-19

 

you can follow the guidance of the American Medical Association, or some random person on the internet. Up to you.

 

 

I think you and I are in the minority.

 

The majority seem to find it much more exciting to follow complete loons on YouTube.

[rumak]

On 7/23/2021 at 10:41 PM, connda said:

You could go the other way around.  Lets talk Albendazole.  $1 USD here.  $200 to $800 in the US per 400mg dose.
Now tell me.  The pharmaceutical companies worldwide are not greedy, evil inhuman vile bastards?  They are.

How about this one.   Harvoni,  a drug that taken as a single pill for 90 days will cure hepatitis c for over 90% of the patients.  Cost ?  An eight-week treatment course is approximately $65,000, a 12-week course is $98,500, and a 24-week course around $197,000 without insurance or funding.

(insurance of course has "conditions" !   

Ahhh,  but now they finally allow a generic to be sold in the US  .  Approx cost around 30k dollars for the 3 months !!

Then there is the generic made in India.   Same ingredients and under the patent of Gilead .  Cost ?

Around 1500 dollars total !!    Is it allowed to be sold in other countries  .   Heck no ! 

how many people have hep C  ?  Globally, an estimated 58 million people have chronic hepatitis C virus.        Drug companies :   sorry,  if you can't afford it just die .  not our problem

Yes, i know,  probably off topic 

[canthai55]

3 hours ago, rumak said:

How about this one.   Harvoni,  a drug that taken as a single pill for 90 days will cure hepatitis c for over 90% of the patients.  Cost ?  An eight-week treatment course is approximately $65,000, a 12-week course is $98,500, and a 24-week course around $197,000 without insurance or funding.

(insurance of course has "conditions" !   

Ahhh,  but now they finally allow a generic to be sold in the US  .  Approx cost around 30k dollars for the 3 months !!

Then there is the generic made in India.   Same ingredients and under the patent of Gilead .  Cost ?

Around 1500 dollars total !!    Is it allowed to be sold in other countries  .   Heck no ! 

how many people have hep C  ?  Globally, an estimated 58 million people have chronic hepatitis C virus.        Drug companies :   sorry,  if you can't afford it just die .  not our problem

Yes, i know,  probably off topic 

Harvoni is what I took for 12 weeks.

Course of treatment the year before with different drugs did not get rid of the Hep C

 

[canthai55]

5 hours ago, Danderman123 said:

Why ivermectin should not be used to prevent or treat COVID-19

 

you can follow the guidance of the American Medical Association, or some random person on the internet. Up to you.

 

 

We all know that the AMA is also in bed with Big Pharma

Doctors get kick backs for giving drugs to their patients - Hardly a ringing endorsement for impartiality - or Ethics.

Quite the opposite

[Danderman123]

11 minutes ago, canthai55 said:

We all know that the AMA is also in bed with Big Pharma

Doctors get kick backs for giving drugs to their patients - Hardly a ringing endorsement for impartiality - or Ethics.

Quite the opposite

On one hand, we have the medical and scientific communities, on the other, we have anonymous guy on the internet. Who to believe? 

[heybruce]

9 hours ago, canthai55 said:

We all know that the AMA is also in bed with Big Pharma

Doctors get kick backs for giving drugs to their patients - Hardly a ringing endorsement for impartiality - or Ethics.

Quite the opposite

"We all know that..."  always precedes a statement that the poster has no credible evidence to support.

 

There is also no credible evidence to support Ivermectin as a Covid 19 treatment.

[Danderman123]

Texan Man Who Organized Anti-Mask Protests Dies of COVID

 

Wallace started experiencing typical COVID-19 symptoms on July 26, including fever and cough. At first, he refused to get tested or go to the hospital. “He was so hard-headed,” Jessica Wallace told the San Angelo Standard-Times. “He didn’t want to see a doctor, because he didn’t want to be part of the statistics with COVID tests.” At first he tried to self-medicate with Vitamin C, zinc aspirin, an inhaler, and ivermectin tablets. But a few days later, a relative took him to the emergency room.

[pomchop]

Can't fix stupid?  Covid seems to often fix stupid.

[Harveyg]

On 8/29/2021 at 1:13 AM, Danderman123 said:

Texan Man Who Organized Anti-Mask Protests Dies of COVID

 

Wallace started experiencing typical COVID-19 symptoms on July 26, including fever and cough. At first, he refused to get tested or go to the hospital. “He was so hard-headed,” Jessica Wallace told the San Angelo Standard-Times. “He didn’t want to see a doctor, because he didn’t want to be part of the statistics with COVID tests.” At first he tried to self-medicate with Vitamin C, zinc aspirin, an inhaler, and ivermectin tablets. But a few days later, a relative took him to the emergency room.

The issue isn’t to cherry pick to make your point. The issue is, overall, does this kind of protocol help people substantially, significantly, or not.  Take a look at this interview everyone, and Judge for yourselves.

 

 

[Rimmer]

A post with a link to a pseudoscience scaremongering conspiracy website has been removed

[rumak]

On 8/28/2021 at 3:33 PM, Danderman123 said:

On one hand, we have the medical and scientific communities, on the other, we have anonymous guy on the internet. Who to believe? 

well,  i think the smartest guys posting here believe the anonymous guy  ????

[canthai55]

On 8/28/2021 at 3:33 PM, Danderman123 said:

On one hand, we have the medical and scientific communities, on the other, we have anonymous guy on the internet. Who to believe? 

Says an anonymous guy on the internet.

 

[Tony125]

On 8/29/2021 at 3:13 PM, Danderman123 said:

Texan Man Who Organized Anti-Mask Protests Dies of COVID

 

Wallace started experiencing typical COVID-19 symptoms on July 26, including fever and cough. At first, he refused to get tested or go to the hospital. “He was so hard-headed,” Jessica Wallace told the San Angelo Standard-Times. “He didn’t want to see a doctor, because he didn’t want to be part of the statistics with COVID tests.” At first he tried to self-medicate with Vitamin C, zinc aspirin, an inhaler, and ivermectin tablets. But a few days later, a relative took him to the emergency room.

The study that 'should basically end any scientific debate' about masks

 

https://www.yahoo.com/news/study-basically-end-scientific-debate-144802638.html

[EricTh]

On 8/28/2021 at 3:20 PM, canthai55 said:

We all know that the AMA is also in bed with Big Pharma

Doctors get kick backs for giving drugs to their patients - Hardly a ringing endorsement for impartiality - or Ethics.

Quite the opposite

 

Unfortunately, most people would rather believe in 'official results' published by the Big Pharma than research done by more ethical people such as Eric Berg (watch his videos).

 

That's how the Big Pharma controls the medicine industry and gets super-rich.

 

[heybruce]

11 hours ago, Harveyg said:

The issue isn’t to cherry pick to make your point. The issue is, overall, does this kind of protocol help people substantially, significantly, or not.  Take a look at this interview everyone, and Judge for yourselves.

 

 

Tens of thousands of self-reported Adverse Drug Reactions (ADR) following tens of millions of vaccinations (so about one in a thousand, most of the ADR's temporary and not life-threatening), no causative links to the vaccines found, death rates from Covid 19 plummeted after the vaccinations of a large portion of the population.

 

https://healthfeedback.org/claimreview/yellow-card-scheme-for-adverse-events-does-not-suggest-any-new-side-effects-of-covid-19-vaccines-tess-lawrie/

[heybruce]

6 hours ago, EricTh said:

 

Unfortunately, most people would rather believe in 'official results' published by the Big Pharma than research done by more ethical people such as Eric Berg (watch his videos).

 

That's how the Big Pharma controls the medicine industry and gets super-rich.

 

Eric Berg the vitamin peddler?  What has he got to do with Ivermectin?

[heybruce]

11 hours ago, rumak said:

well,  i think the smartest guys posting here believe the anonymous guy  ????

Is that a joke?  If not, I'm curious as to how you measure intelligence.

[canthai55]

27 minutes ago, heybruce said:

Is that a joke?  If not, I'm curious as to how you measure intelligence.

I measure it - one way - by people who take the time to listen to other people, hear differing opinions, consider alternatives.

Not jump with both feet on any idea that does not fit their pre-conceived idea of what is 'Right'.

Someone who follows Big Gov't - or big anything with mindless enthusiasm.

Those who are very sure of what they know do not really know very much.

 

[canthai55]

There is that anonymous guy on the internet again !

Posting - as they say in court - "Facts not in Evidence" 555

[heybruce]

43 minutes ago, canthai55 said:

I measure it - one way - by people who take the time to listen to other people, hear differing opinions, consider alternatives.

Not jump with both feet on any idea that does not fit their pre-conceived idea of what is 'Right'.

Someone who follows Big Gov't - or big anything with mindless enthusiasm.

Those who are very sure of what they know do not really know very much.

 

I see.  Verifiable facts, data, numbers, peer reviewed studies...stuff like that doesn't enter into it, right?

 

Your approach seems open to personal bias; you believe those who confirm what you want to believe.  I'll go with well conducted studies and facts.

[Danderman123]

The medical community urges people to follow the advice of their doctor and not use Ivermectin as a cure for Covid19.

 

Pharmacy Groups Call for Immediate End to Prescribing, Dispensing Ivermectin for COVID-19 Outside of Clinical Trials

[canthai55]

I remember Nancy Reagan - you know, wife of the liar, thief, crook, and all around bad apple.

Just Say No - marijuana is bad, has no medicinal value, yadda yadda yadda

And now - how times have changed.

Just keep on being spoon fed, keep on believing established liars who are out for your $$$ and have no interest in your well being - ZERO

Gullible ? Senile ? Fluffy coat made of wool ? 555

[EricTh]

3 hours ago, heybruce said:

Eric Berg the vitamin peddler?  What has he got to do with Ivermectin?

If you want to enrich the Big Pharma, that's your choice but we have alternative sources.

 

Eric Berg is NOT a vitamin peddler but a researcher who gives alternative information as to what the Big Pharma feeds the gullible public.