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Dementia and the Shingles Vaccine: New Canadian Study

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Another study (different from the one in Wales mentioned earlier) showing a reduced dementia risk after shingles vaccination.

Vaccination against herpes zoster (shingles) was tied to significantly less dementia risk, data from Canada's network of primary care records showed.

[...]

The findings were similar to ones that emerged in other cohorts, including a "natural experiment" of older adults in Wales from Geldsetzer and colleagues in which herpes zoster vaccine eligibility was determined by birthdate.

Link not requiring free registration:

https://archive.ph/XorBe

Original link:

https://www.medpagetoday.com/neurology/dementia/119592

(Something strange going on with the line spacing above - can't fix it).

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  • Was the research sponsored by the vaccine makers?

  • GroveHillWanderer
    GroveHillWanderer

    No, it was not. As per the info in The Lancet, funding came from the following organisations: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00455-7/fulltext

  • PoorSucker
    PoorSucker

    Get the vaccine, I'm still in pain from shingles since April last year, now my GF has it also. She says it worse than childbirth. Nowadays it's just pain, not like jumping off the balcony pain anymor

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After experience my own mother her last years now before ending up on a caring home, made me decide to get the vaccine. Cost me 15 000,- baht in Norway, anyone knows the price here?

Was the research sponsored by the vaccine makers?

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3 minutes ago, nexus7 said:

Was the research sponsored by the vaccine makers?

No, it was not. As per the info in The Lancet, funding came from the following organisations:

National Institute on Aging, National Institute of Allergy and Infectious Diseases, Stanford Center for Digital Health, Stanford Knight Initiative for Brain Resilience, Biohub

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00455-7/fulltext

2 hours ago, Hummin said:

After experience my own mother her last years now before ending up on a caring home, made me decide to get the vaccine. Cost me 15 000,- baht in Norway, anyone knows the price here?

Are there any after effects of the vaccine. As I had a cold, my pharmacy advised me to have it when better as it can make you very tired for a day or two. Im wondering as I’ll be traveling soon.

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11 minutes ago, geisha said:

Are there any after effects of the vaccine. As I had a cold, my pharmacy advised me to have it when better as it can make you very tired for a day or two. Im wondering as I’ll be traveling soon.

According to the UK "Green Book" information:

The safety of Shingrix® has been evaluated in clinical trials; in those aged 50 years and above the most frequently reported side effects were pain at the injection site (68%), myalgia (33%), and fatigue (32%). Most of these reactions were not long-lasting (median duration 2-3 days).

https://assets.publishing.service.gov.uk/media/689cba1b1c63de6de5bb12a9/Green-book-chapter-Shingles_12_8_24.pdf

(The Green Book is the UK Health Security Agency guide for health professionals on immunisation).

33 minutes ago, geisha said:

Are there any after effects of the vaccine. As I had a cold, my pharmacy advised me to have it when better as it can make you very tired for a day or two. Im wondering as I’ll be traveling soon.

I didn't actually get it yet, but ordered it for my upcoming return.

32 minutes ago, geisha said:

Are there any after effects of the vaccine. As I had a cold, my pharmacy advised me to have it when better as it can make you very tired for a day or two. Im wondering as I’ll be traveling soon.

Your arm may feel as if it has been struck by a baseball bat, and you could feel fatigued the next day.

3 hours ago, Hummin said:

After experience my own mother her last years now before ending up on a caring home, made me decide to get the vaccine. Cost me 15 000,- baht in Norway, anyone knows the price here?

In chiang Rai, 6900 bht for the first shot, 6100 for the next 3 months later.

48 minutes ago, geisha said:

Are there any after effects of the vaccine. As I had a cold, my pharmacy advised me to have it when better as it can make you very tired for a day or two. Im wondering as I’ll be traveling soon.

I had an aching arm for about 36 hours.

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Recently, I had the latest Flu vaccine in my left arm and a first Shingles in my right arm, at the same time at the local pharmacy.

A few days later, I went through the full body scanner at the airport.

I was pulled out for a manual scan with a wand; it went right to the injection site for the Shingles vaccine. The operator showed me the scan on his screen and it clearly light up on the injection site in the arm; he seemed just as confused as I was; he was busy and waved me on.

A few days ago, I went back for the second Shingles vaccine, I told the story to the pharmacist, and I asked if there was metallic materials in the vaccine, I think he thought I was joking.

I googled it and the explanation seems to be that the body scanner picks up changes in density and presumably the injection site was inflamed to some degree. Bit hard to believe, as there could many places in the body where similar is happening, and so many false flags.

I did not have any side effects from the vaccinations other than a sore arm for about 2 days. That’s my experience with the Shingles vaccine.

3 hours ago, Hummin said:

After experience my own mother her last years now before ending up on a caring home, made me decide to get the vaccine. Cost me 15 000,- baht in Norway, anyone knows the price here?

6k at the Chiang Rai public hospital this past Summer.

1 hour ago, geisha said:

Are there any after effects of the vaccine. As I had a cold, my pharmacy advised me to have it when better as it can make you very tired for a day or two. Im wondering as I’ll be traveling soon.

Nothing major, arm a little sore, no big deal, kinda standard, they warned that you may feel off for a couple days (can't remember the exact words they used), anyway i was fine

1 hour ago, cjinchiangrai said:

6k at the Chiang Rai public hospital this past Summer.

one shot, or two?

2 hours ago, nexus7 said:

Was the research sponsored by the vaccine makers?

2 hours ago, GroveHillWanderer said:

No, it was not. As per the info in The Lancet, funding came from the following organisations:

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00455-7/fulltext

Ah-huh. But according to an AI search, those organization sleep in the same beds as drug makers. Per Grok AI:

"Yes, several of these organizations have links to pharmaceutical companies, primarily through partnerships, collaborations, funding arrangements, or public-private initiatives focused on research, drug development, and technology advancement.

  • National Institute on Aging (NIA): Yes, strong links. NIA participates in the Accelerating Medicines Partnership® Program for Alzheimer's Disease (AMP® AD), a public-private partnership with the NIH, FDA, multiple biopharmaceutical and life science companies, and nonprofits. This involves sharing expertise, resources (over $400 million including in-kind contributions), and joint efforts to identify therapeutic targets and biomarkers for Alzheimer's. Private partners have included companies like Eisai Inc., Takeda Pharmaceutical Company Limited, and GlaxoSmithKline (GSK). NIA also supports public-private partnerships for drug repositioning and has funded collaborations that advance Alzheimer's research with industry involvement. 👈 Yep!

  • National Institute of Allergy and Infectious Diseases (NIAID): Yes, significant links. NIAID has a track record of partnerships with pharmaceutical companies for research on infectious diseases, vaccines, and therapeutics. Examples include collaborations during COVID-19 (e.g., ACTIV partnership with 16 drug companies to accelerate treatments and vaccines), Ebola vaccine trials with GlaxoSmithKline (GSK), and ongoing cooperative research agreements (CRADAs), contracts, and licensing with biotech/pharma firms. NIAID promotes domestic and international partnerships to advance product development, including with companies like Microbiotix. 👈 Yep!

  • Stanford Center for Digital Health: Yes, direct links via industry partnerships. It runs an Industry Affiliates Program designed to foster collaborations between academia and industry (including pharma and tech companies) to advance digital health innovations. This includes membership levels for companies to collaborate on projects, faculty site visits, and research support aligned with business objectives. Stanford Medicine broadly facilitates strategic industry partnerships, including with digital health and tech firms that often intersect with pharmaceutical applications. 👈 Yep!

  • Stanford Knight Initiative for Brain Resilience: Limited or no direct evidence of pharmaceutical company links. This initiative (funded primarily by a $75 million gift from Phil and Penny Knight of Nike) focuses on academic research into brain aging, neurodegeneration, and resilience, with grants for Stanford-based projects. It emphasizes interdisciplinary academic work and does not prominently feature pharmaceutical partnerships or industry funding in available information. 👈 Yay! One that doesn't!

  • Biohub (referring to Chan Zuckerberg Biohub): Yes, some links, though more indirect or collaborative. The CZ Biohub (part of the Chan Zuckerberg Initiative) focuses on biomedical research and has engaged in partnerships related to disease research, including COVID-19 efforts and rare diseases. It has collaborated on projects involving biotech firms (e.g., Cellarity for machine learning in single-cell analysis) and broader networks that include industry elements, but it is not primarily pharma-driven. Ties are more to philanthropy, academia, and emerging biotech rather than traditional large pharmaceutical companies. 👈 And kinda, sorta!

In summary, the government institutes (NIA and NIAID) and Stanford's digital health center show the clearest and most extensive connections to pharmaceutical companies through formal partnerships and collaborative programs aimed at translating research into treatments. The others have fewer or more academia-focused ties."

So the funding is back-doored into the research via organizations linked to Big Pharma. But Big Pharma is one degree removed from the funding the the research that will directly effect revenue and sales of their vaccine by people who aren't skeptical enough to question their interconnections and answer the question Cui Bono (Who Benefits).

Really - if you want the Shingles vaccine, then get the shingles vaccine. But I've read the research. Using relative efficacy (Relative Risk Reduction) that vaccine looks brilliant. RRR at 90%. Look at the absolute efficacy (Absolute Risk Reduction) and I'm personally not sold on it. My research indicated that ARR is as low a 3 people per 1000 who would not get shingles as compared to a placebo. ARR ranges from 0.27 to 3.3 from my own reading. If ARR was 90, I'd go out and get the vaccine tomorrow. But between 0.27 and 3.3? I just don't see the benefit. Btw. Women and people with family history of shingles are at the highest risk. I'm not a woman and no one in my family has ever had shingles. Do I trust the research on decreasing dementia. Not particularly.

I'm not trying to change anyone's mind. Informed Consent means - Do Your Own Research - obtain your own facts, make the choice that is right for you. If YOU believe that the vaccine is 90% effective AND keeps you from getting dementia - please! Go get the shot.

  • Popular Post

Get the vaccine, I'm still in pain from shingles since April last year, now my GF has it also.

She says it worse than childbirth.

Nowadays it's just pain, not like jumping off the balcony pain anymore.

Yes it was that bad.

5 hours ago, Hummin said:

After experience my own mother her last years now before ending up on a caring home, made me decide to get the vaccine. Cost me 15 000,- baht in Norway, anyone knows the price here?

I am in OZ and a pensioner I get them free

1 minute ago, still kicking said:

I am in OZ and a pensioner I get them free

We are not there yet!

And I'm not a pensioner yet either.

  • Popular Post
13 minutes ago, PoorSucker said:

Get the vaccine, I'm still in pain from shingles since April last year, now my GF has it also.

She says it worse than childbirth.

Nowadays it's just pain, not like jumping off the balcony pain anymore.

Yes it was that bad.

Yes. Anyone who's actually had shingles - as have friends of mine in Oz - will tell you the pain is enough to make you get the vaccine even if the risk of catching it is low.

ie It's a case of low risk, high penalty.

having watched a few people suffer from Shingles I elected to get Shingrix. Both shots. Weird the prices I am hearing. I am on medicare in the states and have private insurance and don't know which paid for it but cost me nothing.

26 minutes ago, jimmybcool said:

having watched a few people suffer from Shingles I elected to get Shingrix. Both shots. Weird the prices I am hearing. I am on medicare in the states and have private insurance and don't know which paid for it but cost me nothing.

Presumably the medicare and/or private insurance costs you? so doesn't really cost you nothing.

a friend here around 50 just had shingles, didn't seem too bad at all, lucky i guess. I've had one jab already, second jab due in 3 weeks, about 5,500baht for each of two jabs

3 hours ago, GroveHillWanderer said:
4 hours ago, nexus7 said:

Was the research sponsored by the vaccine makers?

No, it was not. As per the info in The Lancet, funding came from the following organisations:

Quote

National Institute on Aging, National Institute of Allergy and Infectious Diseases, Stanford Center for Digital Health, Stanford Knight Initiative for Brain Resilience, Biohub

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00455-7/fulltext

And who sponsored them?

8 minutes ago, scubascuba3 said:

friend here around 50 just had shingles,

My son got shingles at age 11, lasted one week, better get it young but don't immune you for getting it old, vaccination last for eight years.

If you had chicken pox you have the virus dormant.

It's a strange illnesse.

1/3 will get in their lifetime, half over 60 years old

Take that vaccine, was crying in pain.

8 minutes ago, impulse said:

And who sponsored them?

Who cares, when I enlisted in Finland, got four shots same time, pants down...one in each button, one in each arm,

Probably why I live in Thailand 50 years

Was talking to an older relative.

Clear head, asked him if you googled dementia.

Was the links purple? Yes

You have dementia

7 hours ago, Hummin said:

After experience my own mother her last years now before ending up on a caring home, made me decide to get the vaccine. Cost me 15 000,- baht in Norway, anyone knows the price here?

About 6000 baht or a tad less per injection. 2 injections needed.

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