Thai study shows antibody levels after 2 doses of Sinovac drop 50% every 40 days

[webfact]

 

Clinical research has shown that the antibody levels in a person fully inoculated with two doses of the Chinese-made Sinovac vaccine drops by half every 40 days, according to Dr. Anan Jongkaewwattana, a virology researcher at the National Centre for Engineering and Biotechnology (BIOTEC).

 

In his Facebook post on Monday, Dr. Anan said the clinical research was jointly conducted by BIOTEC and the clinical research centre of the Faculty of Medicine of Thammasat University to study the antibody level toward the RBD protein of the COVID-19 virus in 500 samples of people fully inoculated with Sinovac vaccine.

 

The research shows the following:

 

• Their antibody levels have dropped by half over an average of 40 days.
• The antibody levels of those fully inoculated after 60 days are lower than those fully inoculated for fewer than 60 days.
• The antibody levels within 60 days of the second dose are on a par with the efficacy of the vaccines against the original coronavirus variant, which is between 60-70% by average, but among those who are fully inoculated after 60 days, the efficacy of the vaccine dropped to 50%.
• There is no comparative information about the efficacy of the Sinovac vaccine after two doses in protection against the Alpha or Delta variants.
• The level of antibodies tends to drop in line with the ages of those vaccinated, with the level of those who are over 40 lower than their peers who are under 40.

 

Full story: https://www.thaipbsworld.com/thai-study-shows-antibody-levels-after-2-doses-of-sinovac-drop-50-every-40-days/

 

 

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[Fex Bluse]

44 minutes ago, webfact said:

the antibody levels in a person fully inoculated with two doses of the Chinese-made Sinovac vaccine drops by half every 40 days

China won't be happy with this kind of information. 

 

Expect 2 or 3 "studies" in the next couple days that suggest the antibodies last for a hundred years. 

[smedly]

why not just come out a say it

 

sinovac is useless

 

there I just did

 

why don't the WHO revise their recommendations (I think we know why)

[Blumpie]

50 percent of what?  I didn't think this shot did anything for you anyways.  

[Blumpie]

26 minutes ago, smedly said:

why not just come out a say it

 

sinovac is useless

 

there I just did

 

why don't the WHO revise their recommendations (I think we know why)

It's utterly useless.  

I think there is 10 million or so due there shortly by the way.  

[jerrymahoney]

U.S. Officials Press Pfizer for More Evidence of Need for Booster Shot

 

https://www.nytimes.com/2021/07/12/us/politics/pfizer-booster-shots.html  July 12, 2021

 

“Antibody response is not the only measure of immune protection,” said Dr. Leana S. Wen, a former health commissioner for Baltimore. “There have been multiple studies that suggest these vaccines also stimulate B cell and T cell immunity, so even if there isn’t as much antibody, that doesn’t mean someone isn’t protected.”

Edited July 13, 2021 by jerrymahoney

[BE88]

 

I wait for a new vaccine in two or three years 100% guaranteed .

 

 

 

 

 

[JonnyF]

Not too bad. It lasts a couple of weeks longer than most Chinese junk I've bought.

 

Consistent with Thailand's vaccine debacle, they have millions of these on order. Good job Anutin, maybe time for a smug smile and some more lies.

[animalmagic]

With some quick maths on the back of a beer mat that means that after 1 year the Sinovac vaccine is 0.2% effective.

[Bkk Brian]

3 hours ago, webfact said:

There is no comparative information about the efficacy of the Sinovac vaccine after two doses in protection against the Alpha or Delta variants.

So makes this study meaningless aside from knowing what we already knew about how weak it is against other vaccine brands

Edited July 14, 2021 by Bkk Brian

[Blumpie]

2 minutes ago, animalmagic said:

With some quick maths on the back of a beer mat that means that after 1 year the Sinovac vaccine is 0.2% effective.

Sounds about right.  

And the chances of having a bad reaction is probably higher.  

Better get drunk to make your decision if you want to get it or not - more of a chance y ou will actually get it.  

[Caspersfriend]

Published by the BBC:

 

Covid: What do we know about China's coronavirus vaccines?

 

How effective is it?

The WHO said studies showed the Sinovac vaccine "prevented symptomatic disease in 51% of those vaccinated and prevented severe Covid-19 and hospitalization in 100% of the studied population" for adults aged 18 and older, when it approved the jab in June.

It added that only a few adults over the age of 60 were enrolled in clinical trials, so efficacy could not be estimated for that age group.

According to a study published in the New England Journal of Medicine showing results from Chile, Sinovac has an efficacy rate of 65.9% against Covid-19, is 87.5% effective at preventing hospitalisation and 86.3% effective at preventing death.

However, there is little data about its effectiveness against the Delta variant.

 

https://www.bbc.com/news/world-asia-china-57817591

Edited July 14, 2021 by Caspersfriend
Added pic

[JoePai]

1 hour ago, BE88 said:

 

I wait for a new vaccine in two or three years 100% guaranteed .

 

 

 

 

 

Dream on, there is no vaccine with a 100% guarantee

[worgeordie]

Maybe the Sinovac with the jelly in gives longer protection,

or will just give you a blood clot .... rolling eyes Emoji , because still not working..

 

regards Worgeordie 

[ThailandRyan]

On top of that, they believe that by adding a shot of AZ will improve the efficacy and antibodies.  No duh, AstraZenica on its own, even one jab is better than the Sinovac.....However, the WHO has other ideas of whether is would be appropriate.......

[jacko45k]

3 hours ago, smedly said:

why not just come out a say it

 

sinovac is useless

 

there I just did

 

why don't the WHO revise their recommendations (I think we know why)

Certainly looks that way doesn't it....... !

A temporary solution... when people were expecting long term. Many countries that committed to the Chinese vaccine will be having resurgences and have to think again. Just watched a report on Indonesia who seem to be where India was a few months ago now..... they didn't even get to a reasonable vaccination levels. China has a lot to answer for and countries truly need to see this vaccine as a temporary measure until something better can be obtained, or skip over it if possible.

Edited July 14, 2021 by jacko45k

[Artisi]

2 hours ago, Blumpie said:

It's utterly useless.  

I think there is 10 million or so due there shortly by the way.  

That's OK, just moth-ball it along with all the other useless things brought over the yearssuch as an air-craft carrier, blimps, bomb sniffing devices, tanks, personnel carriers etc. 

[smedly]

5 minutes ago, jacko45k said:

Certainly looks that way doesn't it....... !

A temporary solution... when people were expecting long term. Many countries that committed to the Chinese vaccine will be having resurgences and have to think again. Just watched a report on Indonesia who seem to be where India was a few months ago now..... they didn't even get to a reasonable vaccination levels. China has a lot to answer for and countries truly need to see this vaccine as a temporary measure until something better can be obtained, or skip over it if possible.

great post

[Bkk Brian]

18 minutes ago, Caspersfriend said:

Published by the BBC:

 

Covid: What do we know about China's coronavirus vaccines?

 

How effective is it?

The WHO said studies showed the Sinovac vaccine "prevented symptomatic disease in 51% of those vaccinated and prevented severe Covid-19 and hospitalization in 100% of the studied population" for adults aged 18 and older, when it approved the jab in June.

It added that only a few adults over the age of 60 were enrolled in clinical trials, so efficacy could not be estimated for that age group.

According to a study published in the New England Journal of Medicine showing results from Chile, Sinovac has an efficacy rate of 65.9% against Covid-19, is 87.5% effective at preventing hospitalisation and 86.3% effective at preventing death.

However, there is little data about its effectiveness against the Delta variant.

 

https://www.bbc.com/news/world-asia-china-57817591

Any links on how well it did or not, against Delta or Alpha, or Beta for that matter?

[itsari]

16 minutes ago, JoePai said:

Dream on, there is no vaccine with a 100% guarantee

Agree but then the vaccines will be 100 percent tested , unlike now .

[Fex Bluse]

I gotta say if the mRNA vaccines do turn out to cause any long-term harm, the Chinese will have a coup. 

 

Anyway, for now, let's hope the non-China world is right. 

[ThailandRyan]

4 minutes ago, jacko45k said:

Certainly looks that way doesn't it....... !

A temporary solution... when people were expecting long term. Many countries that committed to the Chinese vaccine will be having resurgences and have to think again. Just watched a report on Indonesia who seem to be where India was a few months ago now..... they didn't even get to a reasonable vaccination levels. China has a lot to answer for and countries truly need to see this vaccine as a temporary measure until something better can be obtained, or skip over it if possible.

Wasn't the initial thought that many of the vaccines would be effective for 90 days to 6 months, and then a booster would be needed.  I know that was old information, but then it seems to be true about Sinovac.

[billsmart]

That's still better than having no vaccine... 

[smedly]

22 minutes ago, Caspersfriend said:

However, there is little data about its effectiveness against the Delta variant.

key point making all existing/past studies of sinovac useless, plus the fact there are now serious questions about long term protection and its serious limitations 

[Caspersfriend]

4 minutes ago, Bkk Brian said:

Any links on how well it did or not, against Delta or Alpha, or Beta for that matter?

Only the article itself and links within it. Posted today on BBC ---  https://www.bbc.com/news/world-asia-china-57817591

[DrJack54]

Today 9317

Die 87

[Bkk Brian]

Just now, Caspersfriend said:

Only the article itself and links within it. Posted today on BBC ---  https://www.bbc.com/news/world-asia-china-57817591

Thanks yes I read it, unfortunately no studies carried out on Sinovac with variants of concern, only with the original strain covid-19.

 

The reality is that strain has now all but disappeared in Thailand, with delta the prominent strain we know that Sinovac's effectiveness is nowhere near that claimed in previous studies. 

 

 

[jacko45k]

6 minutes ago, ThailandRyan said:

Wasn't the initial thought that many of the vaccines would be effective for 90 days to 6 months, and then a booster would be needed.  I know that was old information, but then it seems to be true about Sinovac.

Have they started booster shot in the UK (for example) yet? I know a pal of mine was told that was likely, but has yet to happen and I believe it is 2 months since his second Pfizer jab. 

It certainly does seem true of Sinovac, and possibly sooner than expected..... 

A vaccination program that takes 12 months to implement will fail if immunity is very low after 6 months!

[smedly]

3 minutes ago, billsmart said:

That's still better than having no vaccine... 

depends, we have to remember that all these vaccines were rushed through without proper testing/study which can take years normally 

 

I have a feeling if sinovac had gone through the proper developement process it would never have reached 2nd base - emergency use saved it from total failure - why Thailand decided to rely heavily on it is another quest that will never be answered - I do have a few thoughts on the matter  

[Lemonltr]

The Sinovac vaccine has scored an impressive Covid 19 effacy rate of 100% when used to protect bat's and pangolin.