Ivermectin: Yes, No or Maybe

[cdemundo]

On 8/30/2021 at 10:05 PM, Neeranam said:

They also make billions from the sale of Covid vaccines. 

Is that true about Merck?

All the vaccines they have worked on have been abandoned or not yet brought to market.

They have some kind of agreement with J&J is that lucrative?

 

[Danderman123]

A Prominent Study Said Ivermectin Prevents COVID, But The Data Is Suspect

 

The Argentine study seems to be bogus.

[mtls2005]

Ivermectin Sheep Drench

This page contains information on Ivermectin Sheep Drench for veterinary use.

The information provided typically includes the following:
Ivermectin Sheep Drench Indications
Warnings and cautions for Ivermectin Sheep Drench
Direction and dosage information for Ivermectin Sheep Drench

 

https://www.drugs.com/vet/ivermectin-sheep-drench.html

 

FDA Approved!

 

 

 

Edited September 5, 2021 by mtls2005

[transam]

Had to smile at this......

 

https://uk.yahoo.com/news/doctor-says-gunshot-victims-forced-154536833.html

[JetsetBkk]

2 hours ago, transam said:

Had to smile at this......

 

https://uk.yahoo.com/news/doctor-says-gunshot-victims-forced-154536833.html

 

And this:

 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088823/

 

Conclusions:

Meta-analyses based on 18 randomized controlled treatment trials of ivermectin in COVID-19 have found large, statistically significant 
reductions in mortality, time to clinical recovery, and time to viral clearance. Furthermore, results from numerous controlled 
prophylaxis trials report significantly reduced risks of contracting COVID-19 with the regular use of ivermectin. Finally, the many 
examples of ivermectin distribution campaigns leading to rapid population-wide decreases in morbidity and mortality indicate that an 
oral agent effective in all phases of COVID-19 has been identified. 

 

[mtls2005]

Proper techniques demonstrated in this video...

 

https://www.youtube.com/watch?v=m0TFBU75DiM

 

[Jeffr2]

Some really stupid people.

 

https://eu.usatoday.com/story/news/factcheck/2021/08/30/fact-check-590-spike-texas-poison-control-calls-ivermectin/5643254001/

 

Between January and August 2020, poison control received 23 calls about ivermectin. In that same time period this year, the state poison control network has received 159 calls about ivermectin – a 591% increase. 

[xylophone]

2 hours ago, JetsetBkk said:

 

And this:

 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088823/

 

Conclusions:

Meta-analyses based on 18 randomized controlled treatment trials of ivermectin in COVID-19 have found large, statistically significant 
reductions in mortality, time to clinical recovery, and time to viral clearance. Furthermore, results from numerous controlled 
prophylaxis trials report significantly reduced risks of contracting COVID-19 with the regular use of ivermectin. Finally, the many 
examples of ivermectin distribution campaigns leading to rapid population-wide decreases in morbidity and mortality indicate that an 
oral agent effective in all phases of COVID-19 has been identified. 

 

Problem being that papers like this published have been discredited one way or another............

 

Misleading clinical evidence and systematic reviews on ivermectin for COVID-19.

Different websites (such as https://ivmmeta.com/, https://c19ivermectin.com/, https://tratamientotemprano.org/estudios-ivermectina/, among others) have conducted meta-analyses with ivermectin studies, showing unpublished colourful forest plots which rapidly gained public acknowledgement and were disseminated via social media, without following any methodological or report guidelines. These websites do not include protocol registration with methods, search strategies, inclusion criteria, quality assessment of the included studies nor the certainty of the evidence of the pooled estimates. Prospective registration of systematic reviews with or without meta-analysis protocols is a key feature for providing transparency in the review process and ensuring protection against reporting biases, by revealing differences between the methods or outcomes reported in the published review and those planned in the registered protocol. These websites show pooled estimates suggesting significant benefits with ivermectin, which has resulted in confusion for clinicians, patients and even decision-makers. This is usually a problem when performing meta-analyses which are not based in rigorous systematic reviews, often leading to spread spurious or fallacious findings.³⁶

 

Concluding, research related to ivermectin in COVID-19 has serious methodological limitations resulting in very low certainty of the evidence, and continues to grow.^37–39 The use of ivermectin, among others repurposed drugs for prophylaxis or treatment for COVID-19, should be done based on trustable evidence, without conflicts of interest, with proven safety and efficacy in patient-consented, ethically approved, randomised clinical trials.

 

https://ebm.bmj.com/content/early/2021/05/26/bmjebm-2021-111678

 

AND with another published paper: 

Larger trials will be needed to confirm these preliminary findings. 

 

https://pubmed.ncbi.nlm.nih.gov/

 

[FridgeMagnet1]

On 9/2/2021 at 2:11 AM, cdemundo said:

Is that true about Merck?

All the vaccines they have worked on have been abandoned or not yet brought to market.

They have some kind of agreement with J&J is that lucrative?

 

Strange isn’t it?

looking through my vaccine records and it’s all Merck and Sanofil Pasteur, yet both giants of the vaccine Industry have completely drawn a blank with COVID19 

[DavisH]

On 6/8/2021 at 10:17 AM, clivebaxter said:

Can you take the cheap version for pets, is is that dangerous?

https://www.ksat.com/news/local/2021/09/01/taking-ivermectin-may-cause-serious-illness-including-hallucinations-and-seizures-cdc-says/

[Chomper Higgot]

3 hours ago, DavisH said:

https://www.ksat.com/news/local/2021/09/01/taking-ivermectin-may-cause-serious-illness-including-hallucinations-and-seizures-cdc-says/

I don’t think hallucinations will dissuade the likely candidates of self medicating with neurotoxins from doing so, they’re living in an alternate reality they’ll probably regard hallucinations as an augmentation or the fool’s bliss they inhabit.

 

A select few, though still too many, within the rightwing evangelical subset of de-wormer imbibers might believe their long awaited rapture has arrived.

 

 

Edited September 5, 2021 by Chomper Higgot

[Jeffr2]

4 hours ago, FridgeMagnet1 said:

Strange isn’t it?

looking through my vaccine records and it’s all Merck and Sanofil Pasteur, yet both giants of the vaccine Industry have completely drawn a blank with COVID19 

Creating an effective vaccine for a brand new virus isn't easy. Hope you understand that.

[Meat Pie 47]

Well doctors must be stupid I watched a program on TV where doctors commented about

Ivermectin and they all agreed "if you are a horse or pig take Ivermectin"

[FridgeMagnet1]

1 hour ago, Jeffr2 said:

Creating an effective vaccine for a brand new virus isn't easy. Hope you understand that.

Yes I understand it very well. Please refer to the comment I was responding to 

[Jeffr2]

51 minutes ago, FridgeMagnet1 said:

Yes I understand it very well. Please refer to the comment I was responding to 

Got you. I apologize.

[placeholder]

Here's an illuminating article about the ivermectin delusion. As the article indicates it's being pushed by vaccine denialists.

How Ivermectin Took Over the COVID Skeptic Internet

https://slate.com/technology/2021/09/ivermectin-covid-misinformation-social-media-grift.html

[mtls2005]

13 hours ago, FridgeMagnet1 said:

Strange isn’t it?

looking through my vaccine records and it’s all Merck and Sanofil Pasteur, yet both giants of the vaccine Industry have completely drawn a blank with COVID19 

 

Why is it "strange"? What is so strange about your vaccination records?

 

Do you often find things which are "strange"?

 

 

Merck Discontinues Development of SARS-CoV-2/COVID-19 Vaccine Candidates; Continues Development of Two Investigational Therapeutic Candidates

 

KENILWORTH, N.J.--(BUSINESS WIRE)-- Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced that the company is discontinuing development of its SARS-CoV-2/COVID-19 vaccine candidates, V590 and V591, and plans to focus its SARS-CoV-2/COVID-19 research strategy and production capabilities on advancing two therapeutic candidates, MK-4482 and MK-7110. This decision follows Merck’s review of findings from Phase 1 clinical studies for the vaccines. In these studies, both V590 and V591 were generally well tolerated, but the immune responses were inferior to those seen following natural infection and those reported for other SARS-CoV-2/COVID-19 vaccines. Merck continues to advance clinical programs and to scale-up manufacturing for two investigational medicines, MK-7110 and MK-4482 (molnupiravir); molnupiravir is being developed in collaboration with Ridgeback Bio.

 

 

https://www.merck.com/news/merck-discontinues-development-of-sars-cov-2-covid-19-vaccine-candidates-continues-development-of-two-investigational-therapeutic-candidates/

 

 

 

I think it's strange that ivermectineers moan about "Big Pharma", while extolling sheep drench developed by Big Pharma. Go figure.

[placeholder]

1 minute ago, mtls2005 said:

 

Why is it "strange"? What is so strange about your vaccination records?

 

Do you often find things which are "strange"?

 

 

Merck Discontinues Development of SARS-CoV-2/COVID-19 Vaccine Candidates; Continues Development of Two Investigational Therapeutic Candidates

 

KENILWORTH, N.J.--(BUSINESS WIRE)-- Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced that the company is discontinuing development of its SARS-CoV-2/COVID-19 vaccine candidates, V590 and V591, and plans to focus its SARS-CoV-2/COVID-19 research strategy and production capabilities on advancing two therapeutic candidates, MK-4482 and MK-7110. This decision follows Merck’s review of findings from Phase 1 clinical studies for the vaccines. In these studies, both V590 and V591 were generally well tolerated, but the immune responses were inferior to those seen following natural infection and those reported for other SARS-CoV-2/COVID-19 vaccines. Merck continues to advance clinical programs and to scale-up manufacturing for two investigational medicines, MK-7110 and MK-4482 (molnupiravir); molnupiravir is being developed in collaboration with Ridgeback Bio.

 

 

https://www.merck.com/news/merck-discontinues-development-of-sars-cov-2-covid-19-vaccine-candidates-continues-development-of-two-investigational-therapeutic-candidates/

 

 

 

I think it's strange that ivermectineers moan about "Big Pharma", while extolling sheep drench developed by Big Pharma. Go figure.

There was also Curevac, a German company and a pioneer in mRNA therapy. Its vaccine failed as well. Fridgemagnet possibly was being ironic, but lots of anti-vaxxers cast suspicion on the vetting process for vaccine. They often claim that the approval is somehow corrupt. But as actual history shows, even the biggest of big pharma companies often fail.

[TheAppletons]

To respond directly to the OP, the answer is "no".  There is no clinical evidence that Ivermectin prevents/cures COVID.  Listen to the scientists, not to Facebook.  Good grief and holy hell.  

[xylophone]

This is an interesting read and IMO gets to the root of the Ivermectin misinformation.......

 

How Ivermectin Took Over the COVID Skeptic Internet

https://slate.com/technology/2021/09/ivermectin-covid-misinformation-social-media-grift.html

 

Ivermectin: the latest unproven COVID treatment to blow up the internet. It’s an anti-parasitic used to treat things like river blindness and lice in humans and, quite commonly, worms and other parasites in horses, cows, and dogs. While there are some clinical trials examining ivermectin as a potential treatment for COVID-19, none have suggested that it reduces the disease. One analysis that touted it as an effective treatment had to be withdrawn for ethical reasons.

 

How did Ivermectin catch people’s attention online as a COVID cure?

I first heard about Ivermectin a couple of months ago.

 

Edited September 22, 2021 by metisdead
Edited as per fair use policy.

[Jeffr2]

10 hours ago, placeholder said:

Here's an illuminating article about the ivermectin delusion. As the article indicates it's being pushed by vaccine denialists.

How Ivermectin Took Over the COVID Skeptic Internet

https://slate.com/technology/2021/09/ivermectin-covid-misinformation-social-media-grift.html

Fox news hosts were also promoting it, along with a bunch of other fake news right wing media outlets. Sad some fall for their lies.

[FridgeMagnet1]

8 hours ago, placeholder said:

There was also Curevac, a German company and a pioneer in mRNA therapy. Its vaccine failed as well. Fridgemagnet possibly was being ironic, but lots of anti-vaxxers cast suspicion on the vetting process for vaccine. They often claim that the approval is somehow corrupt. But as actual history shows, even the biggest of big pharma companies often fail.

No, I find it strange (not suspicious) that two of the biggest vaccine manufacturers in the world, with all their resources and experience, have been unable to produce an effective Covid vaccine.
As I suspect are the EU (and to a lesser extent the UK) who bet big on Sanofil in 2020

 

no suspicion or allegations of a coverup, or claims of Wumao activity or any other paranoid notions. Just that it’s odd that 2 major vaccine manufacturers have seemingly struck a blank (so far) 

[Scott]

A post with unapproved links has been removed.  

 

[cdemundo]

16 hours ago, mtls2005 said:

 

Why is it "strange"? What is so strange about your vaccination records?

 

Do you often find things which are "strange"?

 

 

Merck Discontinues Development of SARS-CoV-2/COVID-19 Vaccine Candidates; Continues Development of Two Investigational Therapeutic Candidates

 

KENILWORTH, N.J.--(BUSINESS WIRE)-- Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced that the company is discontinuing development of its SARS-CoV-2/COVID-19 vaccine candidates, V590 and V591, and plans to focus its SARS-CoV-2/COVID-19 research strategy and production capabilities on advancing two therapeutic candidates, MK-4482 and MK-7110. This decision follows Merck’s review of findings from Phase 1 clinical studies for the vaccines. In these studies, both V590 and V591 were generally well tolerated, but the immune responses were inferior to those seen following natural infection and those reported for other SARS-CoV-2/COVID-19 vaccines. Merck continues to advance clinical programs and to scale-up manufacturing for two investigational medicines, MK-7110 and MK-4482 (molnupiravir); molnupiravir is being developed in collaboration with Ridgeback Bio.

 

 

https://www.merck.com/news/merck-discontinues-development-of-sars-cov-2-covid-19-vaccine-candidates-continues-development-of-two-investigational-therapeutic-candidates/

 

 

 

I think it's strange that ivermectineers moan about "Big Pharma", while extolling sheep drench developed by Big Pharma. Go figure.

["Why is it "strange"? What is so strange about your vaccination records?

Do you often find things which are "strange"?]

 

Wow. Why so hostile?

That was an innocuous remark about how two industry heavy weights had not yet brought a vaccine to market.

 

 

[Jeffr2]

8 hours ago, xylophone said:

Much of what is reported in this review, and that is all it is, has been disproved and one major review in it from which much info was taken, has been withdrawn because it is inaccurate.

 

Sure it is a good treatment for parasites and worms, but even the manufacturer of the drug says it is not useful in treating Covid 19. 

Don't reply. Just report fake news websites like this.

[Danderman123]

Ivermectin and male sterility

[xylophone]

4 minutes ago, Danderman123 said:

Ivermectin and male sterility

BUT........the Ivermectin proponents undying devotion to this anti-parasitic drug will use this as a positive, pointing out its birth control capabilities!!!!!! You can't cure stupid!

[Airalee]

https://pubmed.ncbi.nlm.nih.gov/34145166/
 

Conclusions: Moderate-certainty evidence finds that large reductions in COVID-19 deaths are possible using ivermectin. Using ivermectin early in the clinical course may reduce numbers progressing to severe disease. The apparent safety and low cost suggest that ivermectin is likely to have a significant impact on the SARS-CoV-2 pandemic globally.
 

 

[lucky2008]

I'd choose being a horse over a guinea pig any day. 

 

[Jeffr2]

1 hour ago, lucky2008 said:

I'd choose being a horse over a guinea pig any day. 

 

Many wh'do try this drug are about as smart as a horse.